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Found 39 Enz. Inhib. hit(s) with all data for entry = 50005291
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  1nMAssay Description:Inhibition of Pneumocystis carinii (pc) Dihydrofolate reductaseMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18224(6-[(2,5-dimethoxyphenyl)methyl]-5-methylpyrido[2,3...)
Affinity DataIC50:  1nMAssay Description:Inhibition of rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  3nMAssay Description:Inhibition of rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18268(5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}...)
Affinity DataIC50:  3nMAssay Description:Inhibition of rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18224(6-[(2,5-dimethoxyphenyl)methyl]-5-methylpyrido[2,3...)
Affinity DataIC50:  10nMAssay Description:Inhibition of Toxoplasma gondii (tc) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18268(5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}...)
Affinity DataIC50:  10nMAssay Description:Inhibition of Toxoplasma gondii (tc) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  14nMAssay Description:Inhibition of Toxoplasma gondii (tc) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18224(6-[(2,5-dimethoxyphenyl)methyl]-5-methylpyrido[2,3...)
Affinity DataIC50:  38nMAssay Description:Inhibition of Pneumocystis carinii (pc) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035269(2-{4-[(2,4-Diamino-7H-pyrrolo[2,3-d]pyrimidin-5-yl...)
Affinity DataIC50:  38nMAssay Description:Inhibition of Pneumocystis carinii (pc) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18268(5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}...)
Affinity DataIC50:  42nMAssay Description:Inhibition of Pneumocystis carinii (pc) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035269(2-{4-[(2,4-Diamino-7H-pyrrolo[2,3-d]pyrimidin-5-yl...)
Affinity DataIC50:  44nMAssay Description:Inhibition of rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035269(2-{4-[(2,4-Diamino-7H-pyrrolo[2,3-d]pyrimidin-5-yl...)
Affinity DataIC50:  210nMAssay Description:Inhibition of Toxoplasma gondii (tc) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035274(5-(Naphthalen-1-ylaminomethyl)-7H-pyrrolo[2,3-d]py...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of Toxoplasma gondii (tc) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035273(5-((5,6,7,8-tetrahydronaphthalen-1-ylamino)methyl)...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of Toxoplasma gondii (tc) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035271(5-((2,5-dimethoxyphenylamino)methyl)-7H-pyrrolo[2,...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of Toxoplasma gondii (tc) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18069(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of Toxoplasma gondii (tc) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035268(5-((phenylamino)methyl)-7H-pyrrolo[2,3-d]pyrimidin...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of Toxoplasma gondii (tc) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035272(5-((3,4-dimethoxyphenylamino)methyl)-7H-pyrrolo[2,...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of Toxoplasma gondii (tc) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035276(5-((2,5-diethoxyphenylamino)methyl)-7H-pyrrolo[2,3...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of Toxoplasma gondii (tc) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035270(5-((4-methoxyphenylamino)methyl)-7H-pyrrolo[2,3-d]...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of Toxoplasma gondii (tc) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035275(5-((3,4,5-trimethoxyphenylamino)methyl)-7H-pyrrolo...)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of Toxoplasma gondii (tc) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18069(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of Pneumocystis carinii (pc) Dihydrofolate reductaseMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035273(5-((5,6,7,8-tetrahydronaphthalen-1-ylamino)methyl)...)
Affinity DataIC50:  1.44E+4nMAssay Description:Inhibition of rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035276(5-((2,5-diethoxyphenylamino)methyl)-7H-pyrrolo[2,3...)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of Pneumocystis carinii (pc) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035275(5-((3,4,5-trimethoxyphenylamino)methyl)-7H-pyrrolo...)
Affinity DataIC50: >2.30E+4nMAssay Description:Inhibition of Pneumocystis carinii (pc) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035273(5-((5,6,7,8-tetrahydronaphthalen-1-ylamino)methyl)...)
Affinity DataIC50:  3.53E+4nMAssay Description:Inhibition of Pneumocystis carinii (pc) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035271(5-((2,5-dimethoxyphenylamino)methyl)-7H-pyrrolo[2,...)
Affinity DataIC50:  4.57E+4nMAssay Description:Inhibition of Pneumocystis carinii (pc) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035275(5-((3,4,5-trimethoxyphenylamino)methyl)-7H-pyrrolo...)
Affinity DataIC50:  5.63E+4nMAssay Description:Inhibition of rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035274(5-(Naphthalen-1-ylaminomethyl)-7H-pyrrolo[2,3-d]py...)
Affinity DataIC50:  5.93E+4nMAssay Description:Inhibition of rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035270(5-((4-methoxyphenylamino)methyl)-7H-pyrrolo[2,3-d]...)
Affinity DataIC50:  6.30E+4nMAssay Description:Inhibition of rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035276(5-((2,5-diethoxyphenylamino)methyl)-7H-pyrrolo[2,3...)
Affinity DataIC50:  7.00E+4nMAssay Description:Inhibition of rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035272(5-((3,4-dimethoxyphenylamino)methyl)-7H-pyrrolo[2,...)
Affinity DataIC50:  1.16E+5nMAssay Description:Inhibition of rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035272(5-((3,4-dimethoxyphenylamino)methyl)-7H-pyrrolo[2,...)
Affinity DataIC50:  1.19E+5nMAssay Description:Inhibition of Pneumocystis carinii (pc) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18069(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)
Affinity DataIC50:  1.33E+5nMAssay Description:Inhibition of rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035271(5-((2,5-dimethoxyphenylamino)methyl)-7H-pyrrolo[2,...)
Affinity DataIC50:  1.56E+5nMAssay Description:Inhibition of rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035268(5-((phenylamino)methyl)-7H-pyrrolo[2,3-d]pyrimidin...)
Affinity DataIC50:  2.52E+5nMAssay Description:Inhibition of Pneumocystis carinii (pc) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035268(5-((phenylamino)methyl)-7H-pyrrolo[2,3-d]pyrimidin...)
Affinity DataIC50: >2.52E+5nMAssay Description:Inhibition of rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035270(5-((4-methoxyphenylamino)methyl)-7H-pyrrolo[2,3-d]...)
Affinity DataIC50:  2.79E+5nMAssay Description:Inhibition of Pneumocystis carinii (pc) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035274(5-(Naphthalen-1-ylaminomethyl)-7H-pyrrolo[2,3-d]py...)
Affinity DataIC50:  3.07E+5nMAssay Description:Inhibition of Pneumocystis carinii (pc) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed