Compile Data Set for Download or QSAR
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Found 6 Enz. Inhib. hit(s) with all data for entry = 50030199
TargetIntegrin alpha-L(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50412085(CHEMBL455056)
Affinity DataIC50:  180nMAssay Description:Inhibition of LFA1 expressed in human JY cells interaction with ICAM1-IG expressed in human HeLa cell monolayer after 45 mins by cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50378060(CUCURBITACIN B)
Affinity DataIC50:  300nMAssay Description:Inhibition of LFA1 expressed in human JY cells interaction with ICAM1-IG expressed in human HeLa cell monolayer after 45 mins by cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50412087(CUCURBITACIN I | NSC-521777)
Affinity DataIC50:  950nMAssay Description:Inhibition of LFA1 expressed in human JY cells interaction with ICAM1-IG expressed in human HeLa cell monolayer after 45 mins by cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50412086(CHEMBL492404)
Affinity DataIC50:  1.36E+3nMAssay Description:Inhibition of LFA1 expressed in human JY cells interaction with ICAM1-IG expressed in human HeLa cell monolayer after 45 mins by cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292421(CHEMBL480111 | Cucurbitacin L)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of LFA1 expressed in human JY cells interaction with ICAM1-IG expressed in human HeLa cell monolayer after 45 mins by cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292420(CHEMBL480112 | Cucurbitacin R)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of LFA1 expressed in human JY cells interaction with ICAM1-IG expressed in human HeLa cell monolayer after 45 mins by cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed