Compile Data Set for Download or QSAR
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Found 45 Enz. Inhib. hit(s) with all data for entry = 50005421
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50453625(CHEMBL2110229)
Affinity DataIC50:  0.100nMAssay Description:Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50036787(2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-N-[(R)-1...)
Affinity DataIC50:  0.130nMAssay Description:Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50036787(2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-N-[(R)-1...)
Affinity DataIC50:  0.130nMAssay Description:Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50453625(CHEMBL2110229)
Affinity DataIC50:  0.200nMAssay Description:Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50453616(CHEMBL2110337)
Affinity DataIC50:  0.920nMAssay Description:Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50036790(2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-2-methyl...)
Affinity DataIC50:  1.10nMAssay Description:Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50036790(2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-2-methyl...)
Affinity DataIC50:  1.10nMAssay Description:Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50036806(2-Amino-3-[2,6-dimethyl-4-(4-nitro-benzyloxy)-phen...)
Affinity DataIC50:  3.5nMAssay Description:Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50453616(CHEMBL2110337)
Affinity DataIC50:  4nMAssay Description:Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50453625(CHEMBL2110229)
Affinity DataIC50:  4.40nMAssay Description:Displacement of [3H]-DSLET from rat brain membrane delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50453625(CHEMBL2110229)
Affinity DataIC50:  8nMAssay Description:Inhibitory concentration of the compound was evaluated against delta opioid receptor by the displacement of tritiated DSLET from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50036787(2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-N-[(R)-1...)
Affinity DataIC50:  8.60nMAssay Description:Displacement of [3H]-DSLET from rat brain membrane delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50036793(2-Amino-3-[4-(4-fluoro-benzyloxy)-2,6-dimethyl-phe...)
Affinity DataIC50:  8.70nMAssay Description:Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50036787(2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-N-[(R)-1...)
Affinity DataIC50:  9.60nMAssay Description:Inhibitory concentration of the compound was evaluated against delta opioid receptor by the displacement of tritiated DSLET from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50036805(4-(4-{2-Amino-2-[(R)-1-(3-phenyl-propylcarbamoyl)-...)
Affinity DataIC50:  12.3nMAssay Description:Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50036793(2-Amino-3-[4-(4-fluoro-benzyloxy)-2,6-dimethyl-phe...)
Affinity DataIC50:  17.5nMAssay Description:Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50036802((S)-2-Amino-N-cyclopropylmethyl-3-(4-hydroxy-2,6-d...)
Affinity DataIC50:  23.7nMAssay Description:Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50036802((S)-2-Amino-N-cyclopropylmethyl-3-(4-hydroxy-2,6-d...)
Affinity DataIC50:  23.7nMAssay Description:Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50036797(2-Amino-3-[4-(4-cyano-benzyloxy)-2,6-dimethyl-phen...)
Affinity DataIC50:  28.6nMAssay Description:Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50453629(CHEMBL170594)
Affinity DataIC50:  32nMAssay Description:Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50453628(CHEMBL2110227)
Affinity DataIC50:  45nMAssay Description:Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50453616(CHEMBL2110337)
Affinity DataIC50:  55nMAssay Description:Displacement of [3H]-DSLET from rat brain membrane delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50453629(CHEMBL170594)
Affinity DataIC50:  57nMAssay Description:Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50036790(2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-2-methyl...)
Affinity DataIC50:  64nMAssay Description:Displacement of [3H]-DSLET from rat brain membrane delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50036790(2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-2-methyl...)
Affinity DataIC50:  124nMAssay Description:Inhibitory concentration of the compound was evaluated against delta opioid receptor by the displacement of tritiated DSLET from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50036806(2-Amino-3-[2,6-dimethyl-4-(4-nitro-benzyloxy)-phen...)
Affinity DataIC50:  127nMAssay Description:Displacement of [3H]-DSLET from rat brain membrane delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50453616(CHEMBL2110337)
Affinity DataIC50:  133nMAssay Description:Inhibitory concentration of the compound was evaluated against delta opioid receptor by the displacement of tritiated DSLET from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50036787(2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-N-[(R)-1...)
Affinity DataIC50:  221nMAssay Description:Inhibitory concentration of the compound was evaluated against kappa opioid receptor by displacement of tritiated U-69593 from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50453625(CHEMBL2110229)
Affinity DataIC50:  316nMAssay Description:Inhibitory concentration of the compound was evaluated against kappa opioid receptor by displacement of tritiated U-69593 from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50036793(2-Amino-3-[4-(4-fluoro-benzyloxy)-2,6-dimethyl-phe...)
Affinity DataIC50:  367nMAssay Description:Inhibitory concentration of the compound was evaluated against delta opioid receptor by the displacement of tritiated DSLET from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50036793(2-Amino-3-[4-(4-fluoro-benzyloxy)-2,6-dimethyl-phe...)
Affinity DataIC50:  367nMAssay Description:Inhibitory concentration of the compound was evaluated against delta opioid receptor by the displacement of tritiated DSLET from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50036802((S)-2-Amino-N-cyclopropylmethyl-3-(4-hydroxy-2,6-d...)
Affinity DataIC50:  409nMAssay Description:Displacement of [3H]-DSLET from rat brain membrane delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50036802((S)-2-Amino-N-cyclopropylmethyl-3-(4-hydroxy-2,6-d...)
Affinity DataIC50:  409nMAssay Description:Displacement of [3H]-DSLET from rat brain membrane delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50036794(3-(4-Allyloxy-2,6-dimethyl-phenyl)-2-amino-N-[(R)-...)
Affinity DataIC50:  600nMAssay Description:Displacement of [3H]-DSLET from rat brain membrane delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50036805(4-(4-{2-Amino-2-[(R)-1-(3-phenyl-propylcarbamoyl)-...)
Affinity DataIC50:  882nMAssay Description:Displacement of [3H]-DSLET from rat brain membrane delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50453629(CHEMBL170594)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]-DSLET from rat brain membrane delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50036802((S)-2-Amino-N-cyclopropylmethyl-3-(4-hydroxy-2,6-d...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory concentration of the compound was evaluated against kappa opioid receptor by displacement of tritiated U-69593 from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50036797(2-Amino-3-[4-(4-cyano-benzyloxy)-2,6-dimethyl-phen...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]-DSLET from rat brain membrane delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50036790(2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-2-methyl...)
Affinity DataIC50:  1.38E+3nMAssay Description:Inhibitory concentration of the compound was evaluated against kappa opioid receptor by displacement of tritiated U-69593 from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50453628(CHEMBL2110227)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibitory concentration of the compound was evaluated against delta opioid receptor by the displacement of tritiated DSLET from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50453629(CHEMBL170594)
Affinity DataIC50:  2.09E+3nMAssay Description:Inhibitory concentration of the compound was evaluated against delta opioid receptor by the displacement of tritiated DSLET from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50453616(CHEMBL2110337)
Affinity DataIC50:  2.52E+3nMAssay Description:Inhibitory concentration of the compound was evaluated against kappa opioid receptor by displacement of tritiated U-69593 from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50036793(2-Amino-3-[4-(4-fluoro-benzyloxy)-2,6-dimethyl-phe...)
Affinity DataIC50:  1.08E+4nMAssay Description:Inhibitory concentration of the compound was evaluated against kappa opioid receptor by displacement of tritiated U-69593 from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50453628(CHEMBL2110227)
Affinity DataIC50:  1.75E+4nMAssay Description:Inhibitory concentration of the compound was evaluated against kappa opioid receptor by displacement of tritiated U-69593 from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50453629(CHEMBL170594)
Affinity DataIC50:  1.98E+4nMAssay Description:Inhibitory concentration of the compound was evaluated against kappa opioid receptor by displacement of tritiated U-69593 from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed