BindingDB logo
myBDB logout

PubMed code 8097538

Compile data set for download or QSAR
Found 69 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50034346
PNG
((3aS,9aR) 1-Allyl-2,3,3a,4,9,9a-hexahydro-1H-benzo...)
Show SMILES Oc1cccc2C[C@@H]3[C@H](CCN3CC=C)Cc12
Show InChI InChI=1S/C15H19NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h2-5,12,14,17H,1,6-10H2/t12-,14-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
0.300n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against [3H]U-86,170-labeled dopamine receptor D2 in cloned CHO cells


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50034352
PNG
((3aS,9aR) 1-Propyl-2,3,3a,4,9,9a-hexahydro-1H-benz...)
Show SMILES CCCN1CC[C@@H]2Cc3c(O)cccc3C[C@@H]12
Show InChI InChI=1S/C15H21NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h3-5,12,14,17H,2,6-10H2,1H3/t12-,14-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
0.5n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against [3H]U-86,170-labeled dopamine receptor D2 in cloned CHO cells


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM21393
PNG
(7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...)
Show SMILES CCCN(CCC)C1CCc2cccc(O)c2C1
Show InChI InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
1.60n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50034352
PNG
((3aS,9aR) 1-Propyl-2,3,3a,4,9,9a-hexahydro-1H-benz...)
Show SMILES CCCN1CC[C@@H]2Cc3c(O)cccc3C[C@@H]12
Show InChI InChI=1S/C15H21NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h3-5,12,14,17H,2,6-10H2,1H3/t12-,14-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity for [3H]raclopride-labeled dopamine receptor D2 in rat striatum


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50034352
PNG
((3aS,9aR) 1-Propyl-2,3,3a,4,9,9a-hexahydro-1H-benz...)
Show SMILES CCCN1CC[C@@H]2Cc3c(O)cccc3C[C@@H]12
Show InChI InChI=1S/C15H21NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h3-5,12,14,17H,2,6-10H2,1H3/t12-,14-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity for [3H]raclopride-labeled dopamine receptor D2 in rat striatum


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50034352
PNG
((3aS,9aR) 1-Propyl-2,3,3a,4,9,9a-hexahydro-1H-benz...)
Show SMILES CCCN1CC[C@@H]2Cc3c(O)cccc3C[C@@H]12
Show InChI InChI=1S/C15H21NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h3-5,12,14,17H,2,6-10H2,1H3/t12-,14-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.40n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against [3H]U-86,170-labeled dopamine receptor D2 in cloned CHO cells


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50034346
PNG
((3aS,9aR) 1-Allyl-2,3,3a,4,9,9a-hexahydro-1H-benzo...)
Show SMILES Oc1cccc2C[C@@H]3[C@H](CCN3CC=C)Cc12
Show InChI InChI=1S/C15H19NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h2-5,12,14,17H,1,6-10H2/t12-,14-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
3n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity for [3H]raclopride-labeled dopamine receptor D2 in rat striatum


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50001888
PNG
((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
Show SMILES CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12
Show InChI InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

Article
PubMed
3n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Compound was evaluated for the binding affinity against [3H]U-86,170-labeled D2 sites in cloned CHO cells


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50034319
PNG
((3aS,9aS)-1-Propyl-2,3,3a,4,9,9a-hexahydro-1H-benz...)
Show SMILES CCCN1CC[C@@H]2Cc3c(O)cccc3C[C@H]12
Show InChI InChI=1S/C15H21NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h3-5,12,14,17H,2,6-10H2,1H3/t12-,14+/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
11n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity for [3H]raclopride-labeled dopamine receptor D2 in rat striatum


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50034319
PNG
((3aS,9aS)-1-Propyl-2,3,3a,4,9,9a-hexahydro-1H-benz...)
Show SMILES CCCN1CC[C@@H]2Cc3c(O)cccc3C[C@H]12
Show InChI InChI=1S/C15H21NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h3-5,12,14,17H,2,6-10H2,1H3/t12-,14+/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
11n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity for [3H]raclopride-labeled dopamine receptor D2 in rat striatum


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50034350
PNG
((3aS,9aR) 1-Allyl-5-methoxy-2,3,3a,4,9,9a-hexahydr...)
Show SMILES COc1cccc2C[C@@H]3[C@H](CCN3CC=C)Cc12
Show InChI InChI=1S/C16H21NO/c1-3-8-17-9-7-13-10-14-12(11-15(13)17)5-4-6-16(14)18-2/h3-6,13,15H,1,7-11H2,2H3/t13-,15-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
11n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50034323
PNG
((2 beta-methyl) 8-Methoxy-2-methyl-1-propyl-2,3,3a...)
Show SMILES CCCN1[C@@H](C)C[C@@H]2Cc3cccc(OC)c3C[C@H]12
Show InChI InChI=1S/C17H25NO/c1-4-8-18-12(2)9-14-10-13-6-5-7-17(19-3)15(13)11-16(14)18/h5-7,12,14,16H,4,8-11H2,1-3H3/t12-,14+,16-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
11n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50001955
PNG
((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)
Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31
Show InChI InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
26n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Compound was evaluated for the binding affinity against [3H]U-86,170-labeled D2 sites in cloned CHO cells


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50034347
PNG
((3aS,9aR)-1-(cyclopropylmethyl)-5-methoxy-2,3,3a,4...)
Show SMILES COc1cccc2C[C@@H]3[C@H](CCN3CC3CC3)Cc12
Show InChI InChI=1S/C17H23NO/c1-19-17-4-2-3-13-10-16-14(9-15(13)17)7-8-18(16)11-12-5-6-12/h2-4,12,14,16H,5-11H2,1H3/t14-,16-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
29n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50034312
PNG
((3aS,9aR)-5-Methoxy-2,3,3a,4,9,9a-hexahydro-1H-ben...)
Show SMILES COc1cccc2C[C@H]3NCC[C@@H]3Cc12
Show InChI InChI=1S/C13H17NO/c1-15-13-4-2-3-9-8-12-10(5-6-14-12)7-11(9)13/h2-4,10,12,14H,5-8H2,1H3/t10-,12-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
29n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50034352
PNG
((3aS,9aR) 1-Propyl-2,3,3a,4,9,9a-hexahydro-1H-benz...)
Show SMILES CCCN1CC[C@@H]2Cc3c(O)cccc3C[C@@H]12
Show InChI InChI=1S/C15H21NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h3-5,12,14,17H,2,6-10H2,1H3/t12-,14-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
36n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50034324
PNG
((3aS,9aR) 5-Methoxy-1-propyl-2,3,3a,4,9,9a-hexahyd...)
Show SMILES CCCN1CC[C@@H]2Cc3c(C[C@@H]12)cccc3OC
Show InChI InChI=1S/C16H23NO/c1-3-8-17-9-7-13-10-14-12(11-15(13)17)5-4-6-16(14)18-2/h4-6,13,15H,3,7-11H2,1-2H3/t13-,15-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
37n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50034324
PNG
((3aS,9aR) 5-Methoxy-1-propyl-2,3,3a,4,9,9a-hexahyd...)
Show SMILES CCCN1CC[C@@H]2Cc3c(C[C@@H]12)cccc3OC
Show InChI InChI=1S/C16H23NO/c1-3-8-17-9-7-13-10-14-12(11-15(13)17)5-4-6-16(14)18-2/h4-6,13,15H,3,7-11H2,1-2H3/t13-,15-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
37n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50034350
PNG
((3aS,9aR) 1-Allyl-5-methoxy-2,3,3a,4,9,9a-hexahydr...)
Show SMILES COc1cccc2C[C@@H]3[C@H](CCN3CC=C)Cc12
Show InChI InChI=1S/C16H21NO/c1-3-8-17-9-7-13-10-14-12(11-15(13)17)5-4-6-16(14)18-2/h3-6,13,15H,1,7-11H2,2H3/t13-,15-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
41n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50034346
PNG
((3aS,9aR) 1-Allyl-2,3,3a,4,9,9a-hexahydro-1H-benzo...)
Show SMILES Oc1cccc2C[C@@H]3[C@H](CCN3CC=C)Cc12
Show InChI InChI=1S/C15H19NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h2-5,12,14,17H,1,6-10H2/t12-,14-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
47n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity for [3H]raclopride-labeled dopamine receptor D2 in rat striatum


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50040183
PNG
((3aR,9aS)-1-allyl-2,3,3a,4,9,9a-hexahydro-1H-benzo...)
Show SMILES Oc1cccc2C[C@H]3[C@@H](CCN3CC=C)Cc12
Show InChI InChI=1S/C15H19NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h2-5,12,14,17H,1,6-10H2/t12-,14-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
47n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity for [3H]raclopride-labeled dopamine receptor D2 in rat striatum


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5HT1A)


(Mus musculus (Mouse))
BDBM50034324
PNG
((3aS,9aR) 5-Methoxy-1-propyl-2,3,3a,4,9,9a-hexahyd...)
Show SMILES CCCN1CC[C@@H]2Cc3c(C[C@@H]12)cccc3OC
Show InChI InChI=1S/C16H23NO/c1-3-8-17-9-7-13-10-14-12(11-15(13)17)5-4-6-16(14)18-2/h4-6,13,15H,3,7-11H2,1-2H3/t13-,15-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
55n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Compound was evaluated for the binding affinity against [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in cloned CHO cells


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50034346
PNG
((3aS,9aR) 1-Allyl-2,3,3a,4,9,9a-hexahydro-1H-benzo...)
Show SMILES Oc1cccc2C[C@@H]3[C@H](CCN3CC=C)Cc12
Show InChI InChI=1S/C15H19NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h2-5,12,14,17H,1,6-10H2/t12-,14-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
56n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50034346
PNG
((3aS,9aR) 1-Allyl-2,3,3a,4,9,9a-hexahydro-1H-benzo...)
Show SMILES Oc1cccc2C[C@@H]3[C@H](CCN3CC=C)Cc12
Show InChI InChI=1S/C15H19NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h2-5,12,14,17H,1,6-10H2/t12-,14-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
56n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50034352
PNG
((3aS,9aR) 1-Propyl-2,3,3a,4,9,9a-hexahydro-1H-benz...)
Show SMILES CCCN1CC[C@@H]2Cc3c(O)cccc3C[C@@H]12
Show InChI InChI=1S/C15H21NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h3-5,12,14,17H,2,6-10H2,1H3/t12-,14-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
62n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50034338
PNG
((3aS,9aR)-1-Cyclopropylmethyl-2,3,3a,4,9,9a-hexahy...)
Show SMILES Oc1cccc2C[C@@H]3[C@H](CCN3CC3CC3)Cc12
Show InChI InChI=1S/C16H21NO/c18-16-3-1-2-12-9-15-13(8-14(12)16)6-7-17(15)10-11-4-5-11/h1-3,11,13,15,18H,4-10H2/t13-,15-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
69n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM21393
PNG
(7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...)
Show SMILES CCCN(CCC)C1CCc2cccc(O)c2C1
Show InChI InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
86n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against [3H]U-86,170-labeled dopamine receptor D2 in cloned CHO cells


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50034324
PNG
((3aS,9aR) 5-Methoxy-1-propyl-2,3,3a,4,9,9a-hexahyd...)
Show SMILES CCCN1CC[C@@H]2Cc3c(C[C@@H]12)cccc3OC
Show InChI InChI=1S/C16H23NO/c1-3-8-17-9-7-13-10-14-12(11-15(13)17)5-4-6-16(14)18-2/h4-6,13,15H,3,7-11H2,1-2H3/t13-,15-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
100n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against [3H]U-86,170-labeled dopamine receptor D2 in cloned CHO cells


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50034324
PNG
((3aS,9aR) 5-Methoxy-1-propyl-2,3,3a,4,9,9a-hexahyd...)
Show SMILES CCCN1CC[C@@H]2Cc3c(C[C@@H]12)cccc3OC
Show InChI InChI=1S/C16H23NO/c1-3-8-17-9-7-13-10-14-12(11-15(13)17)5-4-6-16(14)18-2/h4-6,13,15H,3,7-11H2,1-2H3/t13-,15-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
100n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against [3H]U-86,170-labeled dopamine receptor D2 in cloned CHO cells


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50034353
PNG
((3aS,9aR)-1-Allyl-8-methoxy-2,3,3a,4,9,9a-hexahydr...)
Show SMILES COc1cccc2C[C@H]3CCN(CC=C)[C@@H]3Cc12
Show InChI InChI=1S/C16H21NO/c1-3-8-17-9-7-13-10-12-5-4-6-16(18-2)14(12)11-15(13)17/h3-6,13,15H,1,7-11H2,2H3/t13-,15-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
104n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50034338
PNG
((3aS,9aR)-1-Cyclopropylmethyl-2,3,3a,4,9,9a-hexahy...)
Show SMILES Oc1cccc2C[C@@H]3[C@H](CCN3CC3CC3)Cc12
Show InChI InChI=1S/C16H21NO/c18-16-3-1-2-12-9-15-13(8-14(12)16)6-7-17(15)10-11-4-5-11/h1-3,11,13,15,18H,4-10H2/t13-,15-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
118n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity for [3H]raclopride-labeled dopamine receptor D2 in rat striatum


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50034361
PNG
((3aS,9aR)-1-Benzyl-5-methoxy-2,3,3a,4,9,9a-hexahyd...)
Show SMILES COc1cccc2C[C@@H]3[C@H](CCN3Cc3ccccc3)Cc12
Show InChI InChI=1S/C20H23NO/c1-22-20-9-5-8-16-13-19-17(12-18(16)20)10-11-21(19)14-15-6-3-2-4-7-15/h2-9,17,19H,10-14H2,1H3/t17-,19-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
127n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50034344
PNG
((3aS,9aS)-1-Allyl-8-methoxy-2,3,3a,4,9,9a-hexahydr...)
Show SMILES COc1cccc2C[C@H]3CCN(CC=C)[C@H]3Cc12
Show InChI InChI=1S/C16H21NO/c1-3-8-17-9-7-13-10-12-5-4-6-16(18-2)14(12)11-15(13)17/h3-6,13,15H,1,7-11H2,2H3/t13-,15+/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
145n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50040183
PNG
((3aR,9aS)-1-allyl-2,3,3a,4,9,9a-hexahydro-1H-benzo...)
Show SMILES Oc1cccc2C[C@H]3[C@@H](CCN3CC=C)Cc12
Show InChI InChI=1S/C15H19NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h2-5,12,14,17H,1,6-10H2/t12-,14-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
235n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against [3H]U-86,170-labeled dopamine receptor D2 in cloned CHO cells


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50034346
PNG
((3aS,9aR) 1-Allyl-2,3,3a,4,9,9a-hexahydro-1H-benzo...)
Show SMILES Oc1cccc2C[C@@H]3[C@H](CCN3CC=C)Cc12
Show InChI InChI=1S/C15H19NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h2-5,12,14,17H,1,6-10H2/t12-,14-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
235n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against [3H]U-86,170-labeled dopamine receptor D2 in cloned CHO cells


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50034325
PNG
((2 alpha-methyl) 8-Methoxy-2-methyl-1-propyl-2,3,3...)
Show SMILES CCCN1[C@H](C)C[C@@H]2Cc3cccc(OC)c3C[C@H]12
Show InChI InChI=1S/C17H25NO/c1-4-8-18-12(2)9-14-10-13-6-5-7-17(19-3)15(13)11-16(14)18/h5-7,12,14,16H,4,8-11H2,1-3H3/t12-,14-,16+/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
384n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50034345
PNG
((3aS,9aS)-1-Allyl-5-methoxy-2,3,3a,4,9,9a-hexahydr...)
Show SMILES COc1cccc2C[C@H]3[C@H](CCN3CC=C)Cc12
Show InChI InChI=1S/C16H21NO/c1-3-8-17-9-7-13-10-14-12(11-15(13)17)5-4-6-16(14)18-2/h3-6,13,15H,1,7-11H2,2H3/t13-,15+/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
429n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity for [3H]raclopride-labeled dopamine receptor D2 in rat striatum


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50034323
PNG
((2 beta-methyl) 8-Methoxy-2-methyl-1-propyl-2,3,3a...)
Show SMILES CCCN1[C@@H](C)C[C@@H]2Cc3cccc(OC)c3C[C@H]12
Show InChI InChI=1S/C17H25NO/c1-4-8-18-12(2)9-14-10-13-6-5-7-17(19-3)15(13)11-16(14)18/h5-7,12,14,16H,4,8-11H2,1-3H3/t12-,14+,16-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
464n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against [3H]U-86,170-labeled dopamine receptor D2 in cloned CHO cells


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50034318
PNG
((3aS,9aS)-1-Benzyl-5-methoxy-2,3,3a,4,9,9a-hexahyd...)
Show SMILES COc1cccc2C[C@H]3[C@H](CCN3Cc3ccccc3)Cc12
Show InChI InChI=1S/C20H23NO/c1-22-20-9-5-8-16-13-19-17(12-18(16)20)10-11-21(19)14-15-6-3-2-4-7-15/h2-9,17,19H,10-14H2,1H3/t17-,19+/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
465n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity for [3H]raclopride-labeled dopamine receptor D2 in rat striatum


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50040183
PNG
((3aR,9aS)-1-allyl-2,3,3a,4,9,9a-hexahydro-1H-benzo...)
Show SMILES Oc1cccc2C[C@H]3[C@@H](CCN3CC=C)Cc12
Show InChI InChI=1S/C15H19NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h2-5,12,14,17H,1,6-10H2/t12-,14-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>470n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50040182
PNG
((3aR,9aS)-1-propyl-2,3,3a,4,9,9a-hexahydro-1H-benz...)
Show SMILES CCCN1CC[C@H]2Cc3c(O)cccc3C[C@H]12
Show InChI InChI=1S/C15H21NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h3-5,12,14,17H,2,6-10H2,1H3/t12-,14-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
>470n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50040182
PNG
((3aR,9aS)-1-propyl-2,3,3a,4,9,9a-hexahydro-1H-benz...)
Show SMILES CCCN1CC[C@H]2Cc3c(O)cccc3C[C@H]12
Show InChI InChI=1S/C15H21NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h3-5,12,14,17H,2,6-10H2,1H3/t12-,14-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
>630n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity for [3H]raclopride-labeled dopamine receptor D2 in rat striatum


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50001888
PNG
((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
Show SMILES CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12
Show InChI InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

Article
PubMed
673n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Compound was evaluated for the binding affinity against [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in cloned CHO cells


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50034343
PNG
((3aS,9aS)-1-Cyclopropylmethyl-5-methoxy-2,3,3a,4,9...)
Show SMILES COc1cccc2C[C@H]3[C@H](CCN3CC3CC3)Cc12
Show InChI InChI=1S/C17H23NO/c1-19-17-4-2-3-13-10-16-14(9-15(13)17)7-8-18(16)11-12-5-6-12/h2-4,12,14,16H,5-11H2,1H3/t14-,16+/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
721n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50034343
PNG
((3aS,9aS)-1-Cyclopropylmethyl-5-methoxy-2,3,3a,4,9...)
Show SMILES COc1cccc2C[C@H]3[C@H](CCN3CC3CC3)Cc12
Show InChI InChI=1S/C17H23NO/c1-19-17-4-2-3-13-10-16-14(9-15(13)17)7-8-18(16)11-12-5-6-12/h2-4,12,14,16H,5-11H2,1H3/t14-,16+/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
748n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity for [3H]raclopride-labeled dopamine receptor D2 in rat striatum


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50034324
PNG
((3aS,9aR) 5-Methoxy-1-propyl-2,3,3a,4,9,9a-hexahyd...)
Show SMILES CCCN1CC[C@@H]2Cc3c(C[C@@H]12)cccc3OC
Show InChI InChI=1S/C16H23NO/c1-3-8-17-9-7-13-10-14-12(11-15(13)17)5-4-6-16(14)18-2/h4-6,13,15H,3,7-11H2,1-2H3/t13-,15-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
877n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity for [3H]raclopride-labeled dopamine receptor D2 in rat striatum


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50040182
PNG
((3aR,9aS)-1-propyl-2,3,3a,4,9,9a-hexahydro-1H-benz...)
Show SMILES CCCN1CC[C@H]2Cc3c(O)cccc3C[C@H]12
Show InChI InChI=1S/C15H21NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h3-5,12,14,17H,2,6-10H2,1H3/t12-,14-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
917n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against [3H]U-86,170-labeled dopamine receptor D2 in cloned CHO cells


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50040185
PNG
((3aR,9aS)-1-allyl-5-methoxy-2,3,3a,4,9,9a-hexahydr...)
Show SMILES COc1cccc2C[C@H]3[C@@H](CCN3CC=C)Cc12
Show InChI InChI=1S/C16H21NO/c1-3-8-17-9-7-13-10-14-12(11-15(13)17)5-4-6-16(14)18-2/h3-6,13,15H,1,7-11H2,2H3/t13-,15-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity for [3H]raclopride-labeled dopamine receptor D2 in rat striatum


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50034318
PNG
((3aS,9aS)-1-Benzyl-5-methoxy-2,3,3a,4,9,9a-hexahyd...)
Show SMILES COc1cccc2C[C@H]3[C@H](CCN3Cc3ccccc3)Cc12
Show InChI InChI=1S/C20H23NO/c1-22-20-9-5-8-16-13-19-17(12-18(16)20)10-11-21(19)14-15-6-3-2-4-7-15/h2-9,17,19H,10-14H2,1H3/t17-,19+/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM21393
PNG
(7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...)
Show SMILES CCCN(CCC)C1CCc2cccc(O)c2C1
Show InChI InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity for [3H]raclopride-labeled dopamine receptor D2 in rat striatum


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50034350
PNG
((3aS,9aR) 1-Allyl-5-methoxy-2,3,3a,4,9,9a-hexahydr...)
Show SMILES COc1cccc2C[C@@H]3[C@H](CCN3CC=C)Cc12
Show InChI InChI=1S/C16H21NO/c1-3-8-17-9-7-13-10-14-12(11-15(13)17)5-4-6-16(14)18-2/h3-6,13,15H,1,7-11H2,2H3/t13-,15-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity for [3H]raclopride-labeled dopamine receptor D2 in rat striatum


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50034347
PNG
((3aS,9aR)-1-(cyclopropylmethyl)-5-methoxy-2,3,3a,4...)
Show SMILES COc1cccc2C[C@@H]3[C@H](CCN3CC3CC3)Cc12
Show InChI InChI=1S/C17H23NO/c1-19-17-4-2-3-13-10-16-14(9-15(13)17)7-8-18(16)11-12-5-6-12/h2-4,12,14,16H,5-11H2,1H3/t14-,16-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Compound was evaluated for the binding affinity against [3H]raclopride-labeled dopamine receptor D2 in rat striatum


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50034314
PNG
((3aS,9aS)-5-Methoxy-2,3,3a,4,9,9a-hexahydro-1H-ben...)
Show SMILES COc1cccc2C[C@@H]3NCC[C@@H]3Cc12
Show InChI InChI=1S/C13H17NO/c1-15-13-4-2-3-9-8-12-10(5-6-14-12)7-11(9)13/h2-4,10,12,14H,5-8H2,1H3/t10-,12+/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50034319
PNG
((3aS,9aS)-1-Propyl-2,3,3a,4,9,9a-hexahydro-1H-benz...)
Show SMILES CCCN1CC[C@@H]2Cc3c(O)cccc3C[C@H]12
Show InChI InChI=1S/C15H21NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h3-5,12,14,17H,2,6-10H2,1H3/t12-,14+/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50034345
PNG
((3aS,9aS)-1-Allyl-5-methoxy-2,3,3a,4,9,9a-hexahydr...)
Show SMILES COc1cccc2C[C@H]3[C@H](CCN3CC=C)Cc12
Show InChI InChI=1S/C16H21NO/c1-3-8-17-9-7-13-10-14-12(11-15(13)17)5-4-6-16(14)18-2/h3-6,13,15H,1,7-11H2,2H3/t13-,15+/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50034320
PNG
((3aS,9aS)-5-Methoxy-1-propyl-2,3,3a,4,9,9a-hexahyd...)
Show SMILES CCCN1CC[C@@H]2Cc3c(C[C@H]12)cccc3OC
Show InChI InChI=1S/C16H23NO/c1-3-8-17-9-7-13-10-14-12(11-15(13)17)5-4-6-16(14)18-2/h4-6,13,15H,3,7-11H2,1-2H3/t13-,15+/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>5.00E+3n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50034361
PNG
((3aS,9aR)-1-Benzyl-5-methoxy-2,3,3a,4,9,9a-hexahyd...)
Show SMILES COc1cccc2C[C@@H]3[C@H](CCN3Cc3ccccc3)Cc12
Show InChI InChI=1S/C20H23NO/c1-22-20-9-5-8-16-13-19-17(12-18(16)20)10-11-21(19)14-15-6-3-2-4-7-15/h2-9,17,19H,10-14H2,1H3/t17-,19-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity for [3H]raclopride-labeled dopamine receptor D2 in rat striatum


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50034353
PNG
((3aS,9aR)-1-Allyl-8-methoxy-2,3,3a,4,9,9a-hexahydr...)
Show SMILES COc1cccc2C[C@H]3CCN(CC=C)[C@@H]3Cc12
Show InChI InChI=1S/C16H21NO/c1-3-8-17-9-7-13-10-12-5-4-6-16(18-2)14(12)11-15(13)17/h3-6,13,15H,1,7-11H2,2H3/t13-,15-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Inhibitory concentration against [3H]raclopride-labeled dopamine receptor D2 in rat striatum


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50034324
PNG
((3aS,9aR) 5-Methoxy-1-propyl-2,3,3a,4,9,9a-hexahyd...)
Show SMILES CCCN1CC[C@@H]2Cc3c(C[C@@H]12)cccc3OC
Show InChI InChI=1S/C16H23NO/c1-3-8-17-9-7-13-10-14-12(11-15(13)17)5-4-6-16(14)18-2/h4-6,13,15H,3,7-11H2,1-2H3/t13-,15-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Inhibitory concentration against [3H]raclopride-labeled dopamine receptor D2 in rat striatum


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50040184
PNG
((3aR,9aS)-5-methoxy-1-propyl-2,3,3a,4,9,9a-hexahyd...)
Show SMILES CCCN1CC[C@H]2Cc3c(C[C@H]12)cccc3OC
Show InChI InChI=1S/C16H23NO/c1-3-8-17-9-7-13-10-14-12(11-15(13)17)5-4-6-16(14)18-2/h4-6,13,15H,3,7-11H2,1-2H3/t13-,15-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Inhibitory concentration against [3H]raclopride-labeled dopamine receptor D2 in rat striatum


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50034320
PNG
((3aS,9aS)-5-Methoxy-1-propyl-2,3,3a,4,9,9a-hexahyd...)
Show SMILES CCCN1CC[C@@H]2Cc3c(C[C@H]12)cccc3OC
Show InChI InChI=1S/C16H23NO/c1-3-8-17-9-7-13-10-14-12(11-15(13)17)5-4-6-16(14)18-2/h4-6,13,15H,3,7-11H2,1-2H3/t13-,15+/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Inhibitory concentration against [3H]raclopride-labeled dopamine receptor D2 in rat striatum


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50034312
PNG
((3aS,9aR)-5-Methoxy-2,3,3a,4,9,9a-hexahydro-1H-ben...)
Show SMILES COc1cccc2C[C@H]3NCC[C@@H]3Cc12
Show InChI InChI=1S/C13H17NO/c1-15-13-4-2-3-9-8-12-10(5-6-14-12)7-11(9)13/h2-4,10,12,14H,5-8H2,1H3/t10-,12-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Inhibitory concentration against [3H]raclopride-labeled dopamine receptor D2 in rat striatum


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50034350
PNG
((3aS,9aR) 1-Allyl-5-methoxy-2,3,3a,4,9,9a-hexahydr...)
Show SMILES COc1cccc2C[C@@H]3[C@H](CCN3CC=C)Cc12
Show InChI InChI=1S/C16H21NO/c1-3-8-17-9-7-13-10-14-12(11-15(13)17)5-4-6-16(14)18-2/h3-6,13,15H,1,7-11H2,2H3/t13-,15-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Inhibitory concentration against [3H]raclopride-labeled dopamine receptor D2 in rat striatum


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50034314
PNG
((3aS,9aS)-5-Methoxy-2,3,3a,4,9,9a-hexahydro-1H-ben...)
Show SMILES COc1cccc2C[C@@H]3NCC[C@@H]3Cc12
Show InChI InChI=1S/C13H17NO/c1-15-13-4-2-3-9-8-12-10(5-6-14-12)7-11(9)13/h2-4,10,12,14H,5-8H2,1H3/t10-,12+/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Inhibitory concentration against [3H]raclopride-labeled dopamine receptor D2 in rat striatum


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50034344
PNG
((3aS,9aS)-1-Allyl-8-methoxy-2,3,3a,4,9,9a-hexahydr...)
Show SMILES COc1cccc2C[C@H]3CCN(CC=C)[C@H]3Cc12
Show InChI InChI=1S/C16H21NO/c1-3-8-17-9-7-13-10-12-5-4-6-16(18-2)14(12)11-15(13)17/h3-6,13,15H,1,7-11H2,2H3/t13-,15+/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Inhibitory concentration against [3H]raclopride-labeled dopamine receptor D2 in rat striatum was estimated from single point experiment. compound was...


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50040185
PNG
((3aR,9aS)-1-allyl-5-methoxy-2,3,3a,4,9,9a-hexahydr...)
Show SMILES COc1cccc2C[C@H]3[C@@H](CCN3CC=C)Cc12
Show InChI InChI=1S/C16H21NO/c1-3-8-17-9-7-13-10-14-12(11-15(13)17)5-4-6-16(14)18-2/h3-6,13,15H,1,7-11H2,2H3/t13-,15-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Inhibitory concentration against [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50034323
PNG
((2 beta-methyl) 8-Methoxy-2-methyl-1-propyl-2,3,3a...)
Show SMILES CCCN1[C@@H](C)C[C@@H]2Cc3cccc(OC)c3C[C@H]12
Show InChI InChI=1S/C17H25NO/c1-4-8-18-12(2)9-14-10-13-6-5-7-17(19-3)15(13)11-16(14)18/h5-7,12,14,16H,4,8-11H2,1-3H3/t12-,14+,16-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Inhibitory concentration against [3H]raclopride-labeled dopamine receptor D2 in rat striatum


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50034325
PNG
((2 alpha-methyl) 8-Methoxy-2-methyl-1-propyl-2,3,3...)
Show SMILES CCCN1[C@H](C)C[C@@H]2Cc3cccc(OC)c3C[C@H]12
Show InChI InChI=1S/C17H25NO/c1-4-8-18-12(2)9-14-10-13-6-5-7-17(19-3)15(13)11-16(14)18/h5-7,12,14,16H,4,8-11H2,1-3H3/t12-,14-,16+/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Inhibitory concentration against [3H]raclopride-labeled dopamine receptor D2 in rat striatum


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50040184
PNG
((3aR,9aS)-5-methoxy-1-propyl-2,3,3a,4,9,9a-hexahyd...)
Show SMILES CCCN1CC[C@H]2Cc3c(C[C@H]12)cccc3OC
Show InChI InChI=1S/C16H23NO/c1-3-8-17-9-7-13-10-14-12(11-15(13)17)5-4-6-16(14)18-2/h4-6,13,15H,3,7-11H2,1-2H3/t13-,15-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Compound was evaluated for the binding affinity against [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus


J Med Chem 36: 1069-83 (1993)


Article DOI: 10.1021/jm00060a015
BindingDB Entry DOI: 10.7270/Q2833SPR
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%