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Found 38 Enz. Inhib. hit(s) with all data for entry = 50005807
TargetCoagulation factor X(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM17283((2S)-3-(7-carbamimidoylnaphthalen-2-yl)-2-(4-{[(3S...)
Affinity DataIC50:  70nMAssay Description:In vitro evaluation for the concentration needed for inhibiting factor Xa by 50%More data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041220(1,2-bis(5-amidinobenzofuran-2-yl)ethane | 2-(2-{5-...)
Affinity DataIC50:  100nMAssay Description:In vitro evaluation for the concentration needed for inhibiting factor Xa by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041218(3-(7-Carbamimidoyl-naphthalen-2-yl)-2-{4-[(S)-1-(1...)
Affinity DataIC50:  160nMAssay Description:In vitro evaluation for the concentration needed for inhibiting factor Xa by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041221(3-(7-Carbamimidoyl-naphthalen-2-yl)-2-[4-((S)-pyrr...)
Affinity DataIC50:  200nMAssay Description:In vitro evaluation for the concentration needed for inhibiting factor Xa by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041231(3-(7-Carbamimidoyl-naphthalen-2-yl)-2-[4-((S)-pyrr...)
Affinity DataIC50:  310nMAssay Description:In vitro evaluation for the concentration needed for inhibiting factor Xa by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041219(3-(6-Carbamimidoyl-naphthalen-2-yl)-2-{4-[(S)-1-(1...)
Affinity DataIC50:  360nMAssay Description:In vitro evaluation for the concentration needed for inhibiting factor Xa by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041224((R)-3-(7-Carbamimidoyl-naphthalen-2-yl)-2-{4-[(S)-...)
Affinity DataIC50:  500nMAssay Description:In vitro evaluation for the concentration needed for inhibiting factor Xa by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041217(3-(5-Carbamimidoyl-benzofuran-2-yl)-2-{4-[(S)-1-(1...)
Affinity DataIC50:  500nMAssay Description:In vitro evaluation for the concentration needed for inhibiting factor Xa by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041216(2-(2-{4-[(S)-1-(1-Imino-ethyl)-pyrrolidin-3-yloxy]...)
Affinity DataIC50:  640nMAssay Description:In vitro evaluation for the concentration needed for inhibiting factor Xa by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041223(3-(6-Carbamimidoyl-benzofuran-2-yl)-2-{4-[(S)-1-(1...)
Affinity DataIC50:  840nMAssay Description:In vitro evaluation for the concentration needed for inhibiting factor Xa by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041215(2-{2-[4-((S)-Pyrrolidin-3-yloxy)-phenyl]-ethyl}-be...)
Affinity DataIC50:  940nMAssay Description:In vitro evaluation for the concentration needed for inhibiting factor Xa by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041222(3-(5-Carbamimidoyl-benzofuran-2-yl)-2-[4-((S)-pyrr...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro evaluation for the concentration needed for inhibiting factor Xa by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041226(3-(5-Carbamimidoyl-benzofuran-2-yl)-2-[4-((S)-pyrr...)
Affinity DataIC50:  1.50E+3nMAssay Description:In vitro evaluation for the concentration needed for inhibiting factor Xa by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041227(3-(6-Carbamimidoyl-benzofuran-2-yl)-2-[4-((S)-pyrr...)
Affinity DataIC50:  1.70E+3nMAssay Description:In vitro evaluation for the concentration needed for inhibiting factor Xa by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041214(3-(6-Carbamimidoyl-benzofuran-2-yl)-2-[4-((S)-pyrr...)
Affinity DataIC50:  1.70E+3nMAssay Description:In vitro evaluation for the concentration needed for inhibiting factor Xa by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041216(2-(2-{4-[(S)-1-(1-Imino-ethyl)-pyrrolidin-3-yloxy]...)
Affinity DataIC50:  4.00E+3nMAssay Description:In vitro evaluation for the concentration needed for inhibiting thrombin by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041225(3-(6-Carbamimidoyl-naphthalen-2-yl)-2-[4-((S)-pyrr...)
Affinity DataIC50:  4.10E+3nMAssay Description:In vitro evaluation for the concentration needed for inhibiting factor Xa by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041228(3-(6-Carbamimidoyl-naphthalen-2-yl)-2-[4-((S)-pyrr...)
Affinity DataIC50:  4.20E+3nMAssay Description:In vitro evaluation for the concentration needed for inhibiting factor Xa by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041220(1,2-bis(5-amidinobenzofuran-2-yl)ethane | 2-(2-{5-...)
Affinity DataIC50:  5.00E+3nMAssay Description:In vitro evaluation for the concentration needed for inhibiting thrombin by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041229(2-(5-Carbamimidoyl-benzofuran-2-yl)-3-[4-((S)-pyrr...)
Affinity DataIC50:  9.00E+3nMAssay Description:In vitro evaluation for the concentration needed for inhibiting thrombin by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041217(3-(5-Carbamimidoyl-benzofuran-2-yl)-2-{4-[(S)-1-(1...)
Affinity DataIC50:  1.50E+4nMAssay Description:In vitro evaluation for the concentration needed for inhibiting thrombin by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041230(2-(5-Carbamimidoyl-benzofuran-2-yl)-3-[4-((S)-pyrr...)
Affinity DataIC50:  2.00E+4nMAssay Description:In vitro evaluation for the concentration needed for inhibiting thrombin by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041222(3-(5-Carbamimidoyl-benzofuran-2-yl)-2-[4-((S)-pyrr...)
Affinity DataIC50:  2.10E+4nMAssay Description:In vitro evaluation for the concentration needed for inhibiting thrombin by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041219(3-(6-Carbamimidoyl-naphthalen-2-yl)-2-{4-[(S)-1-(1...)
Affinity DataIC50:  2.20E+4nMAssay Description:In vitro evaluation for the concentration needed for inhibiting thrombin by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041214(3-(6-Carbamimidoyl-benzofuran-2-yl)-2-[4-((S)-pyrr...)
Affinity DataIC50:  3.60E+4nMAssay Description:In vitro evaluation for the concentration needed for inhibiting thrombin by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041228(3-(6-Carbamimidoyl-naphthalen-2-yl)-2-[4-((S)-pyrr...)
Affinity DataIC50:  3.80E+4nMAssay Description:In vitro evaluation for the concentration needed for inhibiting thrombin by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041229(2-(5-Carbamimidoyl-benzofuran-2-yl)-3-[4-((S)-pyrr...)
Affinity DataIC50:  4.50E+4nMAssay Description:In vitro evaluation for the concentration needed for inhibiting factor Xa by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041230(2-(5-Carbamimidoyl-benzofuran-2-yl)-3-[4-((S)-pyrr...)
Affinity DataIC50:  5.20E+4nMAssay Description:In vitro evaluation for the concentration needed for inhibiting factor Xa by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041225(3-(6-Carbamimidoyl-naphthalen-2-yl)-2-[4-((S)-pyrr...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro evaluation for the concentration needed for inhibiting thrombin by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041215(2-{2-[4-((S)-Pyrrolidin-3-yloxy)-phenyl]-ethyl}-be...)
Affinity DataIC50:  1.00E+5nMAssay Description:In vitro evaluation for the concentration needed for inhibiting thrombin by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041226(3-(5-Carbamimidoyl-benzofuran-2-yl)-2-[4-((S)-pyrr...)
Affinity DataIC50:  2.30E+5nMAssay Description:In vitro evaluation for the concentration needed for inhibiting thrombin by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041223(3-(6-Carbamimidoyl-benzofuran-2-yl)-2-{4-[(S)-1-(1...)
Affinity DataIC50: >4.00E+5nMAssay Description:In vitro evaluation for the concentration needed for inhibiting thrombin by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041231(3-(7-Carbamimidoyl-naphthalen-2-yl)-2-[4-((S)-pyrr...)
Affinity DataIC50: >6.00E+5nMAssay Description:In vitro evaluation for the concentration needed for inhibiting thrombin by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041224((R)-3-(7-Carbamimidoyl-naphthalen-2-yl)-2-{4-[(S)-...)
Affinity DataIC50: >1.00E+6nMAssay Description:In vitro evaluation for the concentration needed for inhibiting thrombin by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041227(3-(6-Carbamimidoyl-benzofuran-2-yl)-2-[4-((S)-pyrr...)
Affinity DataIC50: >1.00E+6nMAssay Description:In vitro evaluation for the concentration needed for inhibiting thrombin by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041218(3-(7-Carbamimidoyl-naphthalen-2-yl)-2-{4-[(S)-1-(1...)
Affinity DataIC50: >1.20E+6nMAssay Description:In vitro evaluation for the concentration needed for inhibiting thrombin by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041221(3-(7-Carbamimidoyl-naphthalen-2-yl)-2-[4-((S)-pyrr...)
Affinity DataIC50: >1.60E+6nMAssay Description:In vitro evaluation for the concentration needed for inhibiting thrombin by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM17283((2S)-3-(7-carbamimidoylnaphthalen-2-yl)-2-(4-{[(3S...)
Affinity DataIC50: >2.00E+6nMAssay Description:In vitro evaluation for the concentration needed for inhibiting thrombin by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed