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PubMed code 8201603

Compile data set for download or QSAR
Found 5 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50407165
PNG
(CHEMBL47966)
Show SMILES Oc1ccc(cc1)N=Nc1ccc(O)cc1O
Show InChI InChI=1S/C12H10N2O3/c15-9-3-1-8(2-4-9)13-14-11-6-5-10(16)7-12(11)17/h1-7,15-17H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.80E+4n/an/an/an/an/an/a



University of Nottingham

Curated by ChEMBL


Assay Description
Cytotoxic effect on EGF-receptor overexpressing HN5 squamous carcinoma cells


J Med Chem 37: 1689-95 (1994)


Article DOI: 10.1021/jm00037a020
BindingDB Entry DOI: 10.7270/Q2F47QBV
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50407168
PNG
(CHEMBL44227)
Show SMILES Oc1ccc(cc1)-c1nc2ccc(O)cc2s1
Show InChI InChI=1S/C13H9NO2S/c15-9-3-1-8(2-4-9)13-14-11-6-5-10(16)7-12(11)17-13/h1-7,15-16H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.30E+5n/an/an/an/an/an/a



University of Nottingham

Curated by ChEMBL


Assay Description
Cytotoxic effect on EGF-receptor overexpressing HN5 squamous carcinoma cells


J Med Chem 37: 1689-95 (1994)


Article DOI: 10.1021/jm00037a020
BindingDB Entry DOI: 10.7270/Q2F47QBV
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50407166
PNG
(CHEMBL48085)
Show SMILES Oc1cc(O)c2nc(sc2c1)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C13H9NO4S/c15-7-4-10(18)12-11(5-7)19-13(14-12)6-1-2-8(16)9(17)3-6/h1-5,15-18H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.30E+5n/an/an/an/an/an/a



University of Nottingham

Curated by ChEMBL


Assay Description
Cytotoxic effect on EGF-receptor overexpressing HN5 squamous carcinoma cells


J Med Chem 37: 1689-95 (1994)


Article DOI: 10.1021/jm00037a020
BindingDB Entry DOI: 10.7270/Q2F47QBV
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM7460
PNG
(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...)
Show SMILES Oc1cc(O)c2c(c1)oc(-c1ccc(O)c(O)c1)c(O)c2=O
Show InChI InChI=1S/C15H10O7/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6/h1-5,16-19,21H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
Purchase

CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.90E+5n/an/an/an/an/an/a



University of Nottingham

Curated by ChEMBL


Assay Description
Cytotoxic effect on EGF-receptor overexpressing HN5 squamous carcinoma cells


J Med Chem 37: 1689-95 (1994)


Article DOI: 10.1021/jm00037a020
BindingDB Entry DOI: 10.7270/Q2F47QBV
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50407167
PNG
(CHEMBL45564)
Show SMILES Oc1ccc(cc1)-c1nc2c(O)cc(O)cc2s1
Show InChI InChI=1S/C13H9NO3S/c15-8-3-1-7(2-4-8)13-14-12-10(17)5-9(16)6-11(12)18-13/h1-6,15-17H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.00E+5n/an/an/an/an/an/a



University of Nottingham

Curated by ChEMBL


Assay Description
Cytotoxic effect on EGF-receptor overexpressing HN5 squamous carcinoma cells


J Med Chem 37: 1689-95 (1994)


Article DOI: 10.1021/jm00037a020
BindingDB Entry DOI: 10.7270/Q2F47QBV
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%