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PubMed code 8258820

Compile data set for download or QSAR
Found 47 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Angiotensin II AT2


(RAT)
BDBM50010359
PNG
((S)-5-Diphenylacetyl-1-(4-methoxy-3-methyl-benzyl)...)
Show SMILES COc1ccc(Cn2cnc3CN([C@@H](Cc23)C(O)=O)C(=O)C(c2ccccc2)c2ccccc2)cc1C
Show InChI InChI=1S/C30H29N3O4/c1-20-15-21(13-14-27(20)37-2)17-32-19-31-24-18-33(26(30(35)36)16-25(24)32)29(34)28(22-9-5-3-6-10-22)23-11-7-4-8-12-23/h3-15,19,26,28H,16-18H2,1-2H3,(H,35,36)/t26-/m0/s1
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n/an/a 10n/an/an/an/an/an/a



DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity of the compound towards angitensin II AT2 receptor subtype was determined using rat isolated adrenal cortical microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II AT2


(RAT)
BDBM50043046
PNG
(2-Diphenylacetyl-6-phenyl-1,2,3,4-tetrahydro-isoqu...)
Show SMILES OC(=O)C1Cc2cc(ccc2CN1C(=O)C(c1ccccc1)c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C30H25NO3/c32-29(28(22-12-6-2-7-13-22)23-14-8-3-9-15-23)31-20-25-17-16-24(21-10-4-1-5-11-21)18-26(25)19-27(31)30(33)34/h1-18,27-28H,19-20H2,(H,33,34)
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n/an/a 30n/an/an/an/an/an/a



DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 2 in rat isolated adrenal medullary microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II AT2


(RAT)
BDBM50043035
PNG
(2-Diphenylacetyl-5-pentyl-1,2,3,4-tetrahydro-isoqu...)
Show SMILES CCCCCc1cccc2CN(C(Cc12)C(O)=O)C(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C29H31NO3/c1-2-3-6-12-21-17-11-18-24-20-30(26(29(32)33)19-25(21)24)28(31)27(22-13-7-4-8-14-22)23-15-9-5-10-16-23/h4-5,7-11,13-18,26-27H,2-3,6,12,19-20H2,1H3,(H,32,33)
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n/an/a 40n/an/an/an/an/an/a



DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 2 in rat isolated adrenal medullary microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II AT2


(RAT)
BDBM50010361
PNG
((S)-1-(4-Amino-3-methyl-benzyl)-5-diphenylacetyl-4...)
Show SMILES Cc1cc(Cn2cnc3CN([C@@H](Cc23)C(O)=O)C(=O)C(c2ccccc2)c2ccccc2)ccc1N
Show InChI InChI=1S/C29H28N4O3/c1-19-14-20(12-13-23(19)30)16-32-18-31-24-17-33(26(29(35)36)15-25(24)32)28(34)27(21-8-4-2-5-9-21)22-10-6-3-7-11-22/h2-14,18,26-27H,15-17,30H2,1H3,(H,35,36)/t26-/m0/s1
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n/an/a 40n/an/an/an/an/an/a



DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 2 in rat isolated adrenal medullary microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II AT2


(RAT)
BDBM50043034
PNG
(2-Diphenylacetyl-5-phenyl-1,2,3,4-tetrahydro-isoqu...)
Show SMILES OC(=O)C1Cc2c(CN1C(=O)C(c1ccccc1)c1ccccc1)cccc2-c1ccccc1
Show InChI InChI=1S/C30H25NO3/c32-29(28(22-13-6-2-7-14-22)23-15-8-3-9-16-23)31-20-24-17-10-18-25(21-11-4-1-5-12-21)26(24)19-27(31)30(33)34/h1-18,27-28H,19-20H2,(H,33,34)
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n/an/a 40n/an/an/an/an/an/a



DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 2 in rat isolated adrenal medullary microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II AT2


(RAT)
BDBM50043042
PNG
(2-Diphenylacetyl-5-(4-methoxy-phenyl)-1,2,3,4-tetr...)
Show SMILES COc1ccc(cc1)-c1cccc2CN(C(Cc12)C(O)=O)C(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C31H27NO4/c1-36-25-17-15-21(16-18-25)26-14-8-13-24-20-32(28(31(34)35)19-27(24)26)30(33)29(22-9-4-2-5-10-22)23-11-6-3-7-12-23/h2-18,28-29H,19-20H2,1H3,(H,34,35)
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n/an/a 40n/an/an/an/an/an/a



DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 2 in rat isolated adrenal medullary microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II AT2


(RAT)
BDBM50043033
PNG
(2-Diphenylacetyl-6-phenoxy-1,2,3,4-tetrahydro-isoq...)
Show SMILES OC(=O)C1Cc2cc(Oc3ccccc3)ccc2CN1C(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C30H25NO4/c32-29(28(21-10-4-1-5-11-21)22-12-6-2-7-13-22)31-20-23-16-17-26(35-25-14-8-3-9-15-25)18-24(23)19-27(31)30(33)34/h1-18,27-28H,19-20H2,(H,33,34)
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n/an/a 60n/an/an/an/an/an/a



DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 2 in rat isolated adrenal medullary microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II AT2


(RAT)
BDBM50043038
PNG
(2-Diphenylacetyl-5-(4-methoxy-3-methyl-phenyl)-1,2...)
Show SMILES COc1ccc(cc1C)-c1cccc2CN(C(Cc12)C(O)=O)C(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C32H29NO4/c1-21-18-24(16-17-29(21)37-2)26-15-9-14-25-20-33(28(32(35)36)19-27(25)26)31(34)30(22-10-5-3-6-11-22)23-12-7-4-8-13-23/h3-18,28,30H,19-20H2,1-2H3,(H,35,36)
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n/an/a 70n/an/an/an/an/an/a



DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 2 in rat isolated adrenal medullary microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II receptor


(RAT)
BDBM50043032
PNG
(5-Benzyl-2-diphenylacetyl-1,2,3,4-tetrahydro-isoqu...)
Show SMILES OC(=O)C1Cc2c(Cc3ccccc3)cccc2CN1C(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C31H27NO3/c33-30(29(23-13-6-2-7-14-23)24-15-8-3-9-16-24)32-21-26-18-10-17-25(19-22-11-4-1-5-12-22)27(26)20-28(32)31(34)35/h1-18,28-29H,19-21H2,(H,34,35)
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n/an/a 70n/an/an/an/an/an/a



DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 2 in rat isolated adrenal medullary microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II AT2


(RAT)
BDBM50043032
PNG
(5-Benzyl-2-diphenylacetyl-1,2,3,4-tetrahydro-isoqu...)
Show SMILES OC(=O)C1Cc2c(Cc3ccccc3)cccc2CN1C(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C31H27NO3/c33-30(29(23-13-6-2-7-14-23)24-15-8-3-9-16-24)32-21-26-18-10-17-25(19-22-11-4-1-5-12-22)27(26)20-28(32)31(34)35/h1-18,28-29H,19-21H2,(H,34,35)
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n/an/a 80n/an/an/an/an/an/a



DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 2 in rat isolated adrenal medullary microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II receptor


(RAT)
BDBM50043032
PNG
(5-Benzyl-2-diphenylacetyl-1,2,3,4-tetrahydro-isoqu...)
Show SMILES OC(=O)C1Cc2c(Cc3ccccc3)cccc2CN1C(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C31H27NO3/c33-30(29(23-13-6-2-7-14-23)24-15-8-3-9-16-24)32-21-26-18-10-17-25(19-22-11-4-1-5-12-22)27(26)20-28(32)31(34)35/h1-18,28-29H,19-21H2,(H,34,35)
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n/an/a 90n/an/an/an/an/an/a



DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 2 in rat isolated adrenal medullary microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II AT2


(RAT)
BDBM50043041
PNG
(2-Diphenylacetyl-5-(4-methoxy-benzyl)-1,2,3,4-tetr...)
Show SMILES COc1ccc(Cc2cccc3CN(C(Cc23)C(O)=O)C(=O)C(c2ccccc2)c2ccccc2)cc1
Show InChI InChI=1S/C32H29NO4/c1-37-27-17-15-22(16-18-27)19-25-13-8-14-26-21-33(29(32(35)36)20-28(25)26)31(34)30(23-9-4-2-5-10-23)24-11-6-3-7-12-24/h2-18,29-30H,19-21H2,1H3,(H,35,36)
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n/an/a 90n/an/an/an/an/an/a



DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 2 in rat isolated adrenal medullary microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II AT2


(RAT)
BDBM50043039
PNG
(2-Diphenylacetyl-5-(4-methoxy-3-methyl-benzyl)-1,2...)
Show SMILES COc1ccc(Cc2cccc3CN(C(Cc23)C(O)=O)C(=O)C(c2ccccc2)c2ccccc2)cc1C
Show InChI InChI=1S/C33H31NO4/c1-22-18-23(16-17-30(22)38-2)19-26-14-9-15-27-21-34(29(33(36)37)20-28(26)27)32(35)31(24-10-5-3-6-11-24)25-12-7-4-8-13-25/h3-18,29,31H,19-21H2,1-2H3,(H,36,37)
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n/an/a 100n/an/an/an/an/an/a



DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 2 in rat isolated adrenal medullary microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II AT2


(RAT)
BDBM50043044
PNG
(2-Diphenylcarbamoyl-5-(4-methoxy-benzyl)-1,2,3,4-t...)
Show SMILES COc1ccc(Cc2cccc3CN(C(Cc23)C(O)=O)C(=O)N(c2ccccc2)c2ccccc2)cc1
Show InChI InChI=1S/C31H28N2O4/c1-37-27-17-15-22(16-18-27)19-23-9-8-10-24-21-32(29(30(34)35)20-28(23)24)31(36)33(25-11-4-2-5-12-25)26-13-6-3-7-14-26/h2-18,29H,19-21H2,1H3,(H,34,35)
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n/an/a 200n/an/an/an/an/an/a



DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 2 in rat isolated adrenal medullary microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II AT2


(RAT)
BDBM50043029
PNG
(2-(Methyl-phenyl-carbamoyl)-6-phenoxy-1,2,3,4-tetr...)
Show SMILES CN(C(=O)N1Cc2ccc(Oc3ccccc3)cc2CC1C(O)=O)c1ccccc1
Show InChI InChI=1S/C24H22N2O4/c1-25(19-8-4-2-5-9-19)24(29)26-16-17-12-13-21(30-20-10-6-3-7-11-20)14-18(17)15-22(26)23(27)28/h2-14,22H,15-16H2,1H3,(H,27,28)
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n/an/a 300n/an/an/an/an/an/a



DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 2 in rat isolated adrenal medullary microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II AT2


(RAT)
BDBM50043028
PNG
(2-Diphenylacetyl-5-methyl-1,2,3,4-tetrahydro-isoqu...)
Show SMILES Cc1cccc2CN(C(Cc12)C(O)=O)C(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C25H23NO3/c1-17-9-8-14-20-16-26(22(25(28)29)15-21(17)20)24(27)23(18-10-4-2-5-11-18)19-12-6-3-7-13-19/h2-14,22-23H,15-16H2,1H3,(H,28,29)
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DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 2 in rat isolated adrenal medullary microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II AT2


(RAT)
BDBM50043036
PNG
(5-(4-Methoxy-benzyl)-2-(methyl-phenyl-carbamoyl)-1...)
Show SMILES COc1ccc(Cc2cccc3CN(C(Cc23)C(O)=O)C(=O)N(C)c2ccccc2)cc1
Show InChI InChI=1S/C26H26N2O4/c1-27(21-9-4-3-5-10-21)26(31)28-17-20-8-6-7-19(23(20)16-24(28)25(29)30)15-18-11-13-22(32-2)14-12-18/h3-14,24H,15-17H2,1-2H3,(H,29,30)
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n/an/a 400n/an/an/an/an/an/a



DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 2 in rat isolated adrenal medullary microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II AT2


(RAT)
BDBM50043043
PNG
(2-Diphenylacetyl-6-hydroxy-1,2,3,4-tetrahydro-isoq...)
Show SMILES OC(=O)C1Cc2cc(O)ccc2CN1C(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C24H21NO4/c26-20-12-11-18-15-25(21(24(28)29)14-19(18)13-20)23(27)22(16-7-3-1-4-8-16)17-9-5-2-6-10-17/h1-13,21-22,26H,14-15H2,(H,28,29)
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n/an/a 600n/an/an/an/an/an/a



DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 2 in rat isolated adrenal medullary microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II AT2


(RAT)
BDBM50043031
PNG
(2-Diphenylacetyl-5-(4-methoxy-phenyl)-1,2,3,4-tetr...)
Show SMILES COC(=O)C1Cc2c(CN1C(=O)C(c1ccccc1)c1ccccc1)cccc2-c1ccc(OC)cc1
Show InChI InChI=1S/C32H29NO4/c1-36-26-18-16-22(17-19-26)27-15-9-14-25-21-33(29(20-28(25)27)32(35)37-2)31(34)30(23-10-5-3-6-11-23)24-12-7-4-8-13-24/h3-19,29-30H,20-21H2,1-2H3
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n/an/a 2.00E+3n/an/an/an/an/an/a



DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 2 in rat isolated adrenal medullary microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II AT2


(RAT)
BDBM50043045
PNG
(2-Diphenylacetyl-5-phenyl-1,2,3,4-tetrahydro-isoqu...)
Show SMILES COC(=O)C1Cc2c(CN1C(=O)C(c1ccccc1)c1ccccc1)cccc2-c1ccccc1
Show InChI InChI=1S/C31H27NO3/c1-35-31(34)28-20-27-25(18-11-19-26(27)22-12-5-2-6-13-22)21-32(28)30(33)29(23-14-7-3-8-15-23)24-16-9-4-10-17-24/h2-19,28-29H,20-21H2,1H3
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n/an/a 2.00E+3n/an/an/an/an/an/a



DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 2 in rat isolated adrenal medullary microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II AT2


(RAT)
BDBM50043030
PNG
(2-Diphenylacetyl-1,2,3,4-tetrahydro-isoquinoline-3...)
Show SMILES OC(=O)C1Cc2ccccc2CN1C(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C24H21NO3/c26-23(22(17-9-3-1-4-10-17)18-11-5-2-6-12-18)25-16-20-14-8-7-13-19(20)15-21(25)24(27)28/h1-14,21-22H,15-16H2,(H,27,28)
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n/an/a 2.50E+3n/an/an/an/an/an/a



DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 2 in rat isolated adrenal medullary microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II receptor (AT-1) type-1


(RAT)
BDBM50043032
PNG
(5-Benzyl-2-diphenylacetyl-1,2,3,4-tetrahydro-isoqu...)
Show SMILES OC(=O)C1Cc2c(Cc3ccccc3)cccc2CN1C(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C31H27NO3/c33-30(29(23-13-6-2-7-14-23)24-15-8-3-9-16-24)32-21-26-18-10-17-25(19-22-11-4-1-5-12-22)27(26)20-28(32)31(34)35/h1-18,28-29H,19-21H2,(H,34,35)
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n/an/a 4.00E+3n/an/an/an/an/an/a



DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 1 in rat isolated adrenal cortical microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II receptor (AT-1) type-1


(RAT)
BDBM50043039
PNG
(2-Diphenylacetyl-5-(4-methoxy-3-methyl-benzyl)-1,2...)
Show SMILES COc1ccc(Cc2cccc3CN(C(Cc23)C(O)=O)C(=O)C(c2ccccc2)c2ccccc2)cc1C
Show InChI InChI=1S/C33H31NO4/c1-22-18-23(16-17-30(22)38-2)19-26-14-9-15-27-21-34(29(33(36)37)20-28(26)27)32(35)31(24-10-5-3-6-11-24)25-12-7-4-8-13-25/h3-18,29,31H,19-21H2,1-2H3,(H,36,37)
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n/an/a 5.00E+3n/an/an/an/an/an/a



DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 1 in rat isolated adrenal cortical microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II receptor (AT-1) type-1


(RAT)
BDBM50043032
PNG
(5-Benzyl-2-diphenylacetyl-1,2,3,4-tetrahydro-isoqu...)
Show SMILES OC(=O)C1Cc2c(Cc3ccccc3)cccc2CN1C(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C31H27NO3/c33-30(29(23-13-6-2-7-14-23)24-15-8-3-9-16-24)32-21-26-18-10-17-25(19-22-11-4-1-5-12-22)27(26)20-28(32)31(34)35/h1-18,28-29H,19-21H2,(H,34,35)
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n/an/a 5.00E+3n/an/an/an/an/an/a



DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 1 in rat isolated adrenal cortical microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II AT2


(RAT)
BDBM50043037
PNG
(2-Diphenylacetyl-5-methyl-1,2,3,4-tetrahydro-isoqu...)
Show SMILES COC(=O)C1Cc2c(C)cccc2CN1C(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C26H25NO3/c1-18-10-9-15-21-17-27(23(16-22(18)21)26(29)30-2)25(28)24(19-11-5-3-6-12-19)20-13-7-4-8-14-20/h3-15,23-24H,16-17H2,1-2H3
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n/an/a 5.00E+3n/an/an/an/an/an/a



DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 2 in rat isolated adrenal medullary microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II receptor (AT-1) type-1


(RAT)
BDBM50043041
PNG
(2-Diphenylacetyl-5-(4-methoxy-benzyl)-1,2,3,4-tetr...)
Show SMILES COc1ccc(Cc2cccc3CN(C(Cc23)C(O)=O)C(=O)C(c2ccccc2)c2ccccc2)cc1
Show InChI InChI=1S/C32H29NO4/c1-37-27-17-15-22(16-18-27)19-25-13-8-14-26-21-33(29(32(35)36)20-28(25)26)31(34)30(23-9-4-2-5-10-23)24-11-6-3-7-12-24/h2-18,29-30H,19-21H2,1H3,(H,35,36)
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n/an/a 7.00E+3n/an/an/an/an/an/a



DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 1 in rat isolated adrenal cortical microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II AT2


(RAT)
BDBM50043047
PNG
(5-Benzyl-2-diphenylacetyl-1,2,3,4-tetrahydro-isoqu...)
Show SMILES COC(=O)C1Cc2c(Cc3ccccc3)cccc2CN1C(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C32H29NO3/c1-36-32(35)29-21-28-26(20-23-12-5-2-6-13-23)18-11-19-27(28)22-33(29)31(34)30(24-14-7-3-8-15-24)25-16-9-4-10-17-25/h2-19,29-30H,20-22H2,1H3
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n/an/a 7.00E+3n/an/an/an/an/an/a



DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 2 in rat isolated adrenal medullary microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II receptor (AT-1) type-1


(RAT)
BDBM50043037
PNG
(2-Diphenylacetyl-5-methyl-1,2,3,4-tetrahydro-isoqu...)
Show SMILES COC(=O)C1Cc2c(C)cccc2CN1C(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C26H25NO3/c1-18-10-9-15-21-17-27(23(16-22(18)21)26(29)30-2)25(28)24(19-11-5-3-6-12-19)20-13-7-4-8-14-20/h3-15,23-24H,16-17H2,1-2H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 1 in rat isolated adrenal cortical microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II receptor (AT-1) type-1


(RAT)
BDBM50010361
PNG
((S)-1-(4-Amino-3-methyl-benzyl)-5-diphenylacetyl-4...)
Show SMILES Cc1cc(Cn2cnc3CN([C@@H](Cc23)C(O)=O)C(=O)C(c2ccccc2)c2ccccc2)ccc1N
Show InChI InChI=1S/C29H28N4O3/c1-19-14-20(12-13-23(19)30)16-32-18-31-24-17-33(26(29(35)36)15-25(24)32)28(34)27(21-8-4-2-5-9-21)22-10-6-3-7-11-22/h2-14,18,26-27H,15-17,30H2,1H3,(H,35,36)/t26-/m0/s1
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DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 1 in rat isolated adrenal cortical microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II receptor (AT-1) type-1


(RAT)
BDBM50043028
PNG
(2-Diphenylacetyl-5-methyl-1,2,3,4-tetrahydro-isoqu...)
Show SMILES Cc1cccc2CN(C(Cc12)C(O)=O)C(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C25H23NO3/c1-17-9-8-14-20-16-26(22(25(28)29)15-21(17)20)24(27)23(18-10-4-2-5-11-18)19-12-6-3-7-13-19/h2-14,22-23H,15-16H2,1H3,(H,28,29)
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n/an/a>1.00E+4n/an/an/an/an/an/a



DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 1 in rat isolated adrenal cortical microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II AT2


(RAT)
BDBM50043040
PNG
(2-Diphenylacetyl-5-(4-methoxy-benzyl)-1,2,3,4-tetr...)
Show SMILES COC(=O)C1Cc2c(Cc3ccc(OC)cc3)cccc2CN1C(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C33H31NO4/c1-37-28-18-16-23(17-19-28)20-26-14-9-15-27-22-34(30(21-29(26)27)33(36)38-2)32(35)31(24-10-5-3-6-11-24)25-12-7-4-8-13-25/h3-19,30-31H,20-22H2,1-2H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 2 in rat isolated adrenal medullary microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II receptor (AT-1) type-1


(RAT)
BDBM50043029
PNG
(2-(Methyl-phenyl-carbamoyl)-6-phenoxy-1,2,3,4-tetr...)
Show SMILES CN(C(=O)N1Cc2ccc(Oc3ccccc3)cc2CC1C(O)=O)c1ccccc1
Show InChI InChI=1S/C24H22N2O4/c1-25(19-8-4-2-5-9-19)24(29)26-16-17-12-13-21(30-20-10-6-3-7-11-20)14-18(17)15-22(26)23(27)28/h2-14,22H,15-16H2,1H3,(H,27,28)
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DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 1 in rat isolated adrenal cortical microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II receptor (AT-1) type-1


(RAT)
BDBM50043033
PNG
(2-Diphenylacetyl-6-phenoxy-1,2,3,4-tetrahydro-isoq...)
Show SMILES OC(=O)C1Cc2cc(Oc3ccccc3)ccc2CN1C(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C30H25NO4/c32-29(28(21-10-4-1-5-11-21)22-12-6-2-7-13-22)31-20-23-16-17-26(35-25-14-8-3-9-15-25)18-24(23)19-27(31)30(33)34/h1-18,27-28H,19-20H2,(H,33,34)
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DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 1 in rat isolated adrenal cortical microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II receptor (AT-1) type-1


(RAT)
BDBM50043038
PNG
(2-Diphenylacetyl-5-(4-methoxy-3-methyl-phenyl)-1,2...)
Show SMILES COc1ccc(cc1C)-c1cccc2CN(C(Cc12)C(O)=O)C(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C32H29NO4/c1-21-18-24(16-17-29(21)37-2)26-15-9-14-25-20-33(28(32(35)36)19-27(25)26)31(34)30(22-10-5-3-6-11-22)23-12-7-4-8-13-23/h3-18,28,30H,19-20H2,1-2H3,(H,35,36)
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DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 1 in rat isolated adrenal cortical microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II receptor (AT-1) type-1


(RAT)
BDBM50043043
PNG
(2-Diphenylacetyl-6-hydroxy-1,2,3,4-tetrahydro-isoq...)
Show SMILES OC(=O)C1Cc2cc(O)ccc2CN1C(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C24H21NO4/c26-20-12-11-18-15-25(21(24(28)29)14-19(18)13-20)23(27)22(16-7-3-1-4-8-16)17-9-5-2-6-10-17/h1-13,21-22,26H,14-15H2,(H,28,29)
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DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 2 in rat isolated adrenal medullary microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II receptor (AT-1) type-1


(RAT)
BDBM50043046
PNG
(2-Diphenylacetyl-6-phenyl-1,2,3,4-tetrahydro-isoqu...)
Show SMILES OC(=O)C1Cc2cc(ccc2CN1C(=O)C(c1ccccc1)c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C30H25NO3/c32-29(28(22-12-6-2-7-13-22)23-14-8-3-9-15-23)31-20-25-17-16-24(21-10-4-1-5-11-21)18-26(25)19-27(31)30(33)34/h1-18,27-28H,19-20H2,(H,33,34)
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DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 1 in rat isolated adrenal cortical microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II receptor (AT-1) type-1


(RAT)
BDBM50043036
PNG
(5-(4-Methoxy-benzyl)-2-(methyl-phenyl-carbamoyl)-1...)
Show SMILES COc1ccc(Cc2cccc3CN(C(Cc23)C(O)=O)C(=O)N(C)c2ccccc2)cc1
Show InChI InChI=1S/C26H26N2O4/c1-27(21-9-4-3-5-10-21)26(31)28-17-20-8-6-7-19(23(20)16-24(28)25(29)30)15-18-11-13-22(32-2)14-12-18/h3-14,24H,15-17H2,1-2H3,(H,29,30)
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DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 1 in rat isolated adrenal cortical microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II receptor (AT-1) type-1


(RAT)
BDBM50043047
PNG
(5-Benzyl-2-diphenylacetyl-1,2,3,4-tetrahydro-isoqu...)
Show SMILES COC(=O)C1Cc2c(Cc3ccccc3)cccc2CN1C(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C32H29NO3/c1-36-32(35)29-21-28-26(20-23-12-5-2-6-13-23)18-11-19-27(28)22-33(29)31(34)30(24-14-7-3-8-15-24)25-16-9-4-10-17-25/h2-19,29-30H,20-22H2,1H3
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DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 1 in rat isolated adrenal cortical microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II receptor (AT-1) type-1


(RAT)
BDBM50043044
PNG
(2-Diphenylcarbamoyl-5-(4-methoxy-benzyl)-1,2,3,4-t...)
Show SMILES COc1ccc(Cc2cccc3CN(C(Cc23)C(O)=O)C(=O)N(c2ccccc2)c2ccccc2)cc1
Show InChI InChI=1S/C31H28N2O4/c1-37-27-17-15-22(16-18-27)19-23-9-8-10-24-21-32(29(30(34)35)20-28(23)24)31(36)33(25-11-4-2-5-12-25)26-13-6-3-7-14-26/h2-18,29H,19-21H2,1H3,(H,34,35)
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n/an/a 1.00E+4n/an/an/an/an/an/a



DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 1 in rat isolated adrenal cortical microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II receptor (AT-1) type-1


(RAT)
BDBM50043045
PNG
(2-Diphenylacetyl-5-phenyl-1,2,3,4-tetrahydro-isoqu...)
Show SMILES COC(=O)C1Cc2c(CN1C(=O)C(c1ccccc1)c1ccccc1)cccc2-c1ccccc1
Show InChI InChI=1S/C31H27NO3/c1-35-31(34)28-20-27-25(18-11-19-26(27)22-12-5-2-6-13-22)21-32(28)30(33)29(23-14-7-3-8-15-23)24-16-9-4-10-17-24/h2-19,28-29H,20-21H2,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 1 in rat isolated adrenal cortical microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II receptor (AT-1) type-1


(RAT)
BDBM50043032
PNG
(5-Benzyl-2-diphenylacetyl-1,2,3,4-tetrahydro-isoqu...)
Show SMILES OC(=O)C1Cc2c(Cc3ccccc3)cccc2CN1C(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C31H27NO3/c33-30(29(23-13-6-2-7-14-23)24-15-8-3-9-16-24)32-21-26-18-10-17-25(19-22-11-4-1-5-12-22)27(26)20-28(32)31(34)35/h1-18,28-29H,19-21H2,(H,34,35)
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n/an/a 1.00E+4n/an/an/an/an/an/a



DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 1 in rat isolated adrenal cortical microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II receptor (AT-1) type-1


(RAT)
BDBM50043031
PNG
(2-Diphenylacetyl-5-(4-methoxy-phenyl)-1,2,3,4-tetr...)
Show SMILES COC(=O)C1Cc2c(CN1C(=O)C(c1ccccc1)c1ccccc1)cccc2-c1ccc(OC)cc1
Show InChI InChI=1S/C32H29NO4/c1-36-26-18-16-22(17-19-26)27-15-9-14-25-21-33(29(20-28(25)27)32(35)37-2)31(34)30(23-10-5-3-6-11-23)24-12-7-4-8-13-24/h3-19,29-30H,20-21H2,1-2H3
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DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 1 in rat isolated adrenal cortical microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II receptor (AT-1) type-1


(RAT)
BDBM50043040
PNG
(2-Diphenylacetyl-5-(4-methoxy-benzyl)-1,2,3,4-tetr...)
Show SMILES COC(=O)C1Cc2c(Cc3ccc(OC)cc3)cccc2CN1C(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C33H31NO4/c1-37-28-18-16-23(17-19-28)20-26-14-9-15-27-22-34(30(21-29(26)27)33(36)38-2)32(35)31(24-10-5-3-6-11-24)25-12-7-4-8-13-25/h3-19,30-31H,20-22H2,1-2H3
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DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 1 in rat isolated adrenal cortical microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II receptor (AT-1) type-1


(RAT)
BDBM50043042
PNG
(2-Diphenylacetyl-5-(4-methoxy-phenyl)-1,2,3,4-tetr...)
Show SMILES COc1ccc(cc1)-c1cccc2CN(C(Cc12)C(O)=O)C(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C31H27NO4/c1-36-25-17-15-21(16-18-25)26-14-8-13-24-20-32(28(31(34)35)19-27(24)26)30(33)29(22-9-4-2-5-10-22)23-11-6-3-7-12-23/h2-18,28-29H,19-20H2,1H3,(H,34,35)
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n/an/a 1.00E+4n/an/an/an/an/an/a



DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 1 in rat isolated adrenal cortical microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II receptor (AT-1) type-1


(RAT)
BDBM50043035
PNG
(2-Diphenylacetyl-5-pentyl-1,2,3,4-tetrahydro-isoqu...)
Show SMILES CCCCCc1cccc2CN(C(Cc12)C(O)=O)C(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C29H31NO3/c1-2-3-6-12-21-17-11-18-24-20-30(26(29(32)33)19-25(21)24)28(31)27(22-13-7-4-8-14-22)23-15-9-5-10-16-23/h4-5,7-11,13-18,26-27H,2-3,6,12,19-20H2,1H3,(H,32,33)
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DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 1 in rat isolated adrenal cortical microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II receptor (AT-1) type-1


(RAT)
BDBM50043034
PNG
(2-Diphenylacetyl-5-phenyl-1,2,3,4-tetrahydro-isoqu...)
Show SMILES OC(=O)C1Cc2c(CN1C(=O)C(c1ccccc1)c1ccccc1)cccc2-c1ccccc1
Show InChI InChI=1S/C30H25NO3/c32-29(28(22-13-6-2-7-14-22)23-15-8-3-9-16-23)31-20-24-17-10-18-25(21-11-4-1-5-12-21)26(24)19-27(31)30(33)34/h1-18,27-28H,19-20H2,(H,33,34)
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DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 1 in rat isolated adrenal cortical microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
Angiotensin II receptor (AT-1) type-1


(RAT)
BDBM50043030
PNG
(2-Diphenylacetyl-1,2,3,4-tetrahydro-isoquinoline-3...)
Show SMILES OC(=O)C1Cc2ccccc2CN1C(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C24H21NO3/c26-23(22(17-9-3-1-4-10-17)18-11-5-2-6-12-18)25-16-20-14-8-7-13-19(20)15-21(25)24(27)28/h1-14,21-22H,15-16H2,(H,27,28)
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n/an/a>3.00E+4n/an/an/an/an/an/a



DuPont Merck Pharmaceutical Co.

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II receptor, type 1 in rat isolated adrenal cortical microsomes


J Med Chem 36: 3985-92 (1994)


Article DOI: 10.1021/jm00077a001
BindingDB Entry DOI: 10.7270/Q2CC0ZQT
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%