BindingDB logo
myBDB logout

PubMed code 8411019

Compile data set for download or QSAR
Found 6 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Lck


(Homo sapiens (Human))
BDBM50040294
PNG
(5-[2-(2,5-Dihydroxy-phenyl)-vinyl]-2-hydroxy-benzo...)
Show SMILES OC(=O)c1cc(\C=C\c2cc(O)ccc2O)ccc1O
Show InChI InChI=1S/C15H12O5/c16-11-4-6-13(17)10(8-11)3-1-9-2-5-14(18)12(7-9)15(19)20/h1-8,16-18H,(H,19,20)/b3-1+
PDB

UniProtKB/SwissProt

GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 60n/an/an/an/an/an/a



National Institutes of Health

Curated by ChEMBL


Assay Description
Inhibition of protein-tyrosine kinase p56lck


J Med Chem 36: 3015-20 (1993)


Article DOI: 10.1021/jm00072a023
BindingDB Entry DOI: 10.7270/Q2V123VX
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))
BDBM50038199
PNG
(5-(2,5-Dihydroxy-benzylamino)-2-hydroxy-benzoic ac...)
Show SMILES OC(=O)c1cc(NCc2cc(O)ccc2O)ccc1O
Show InChI InChI=1S/C14H13NO5/c16-10-2-4-12(17)8(5-10)7-15-9-1-3-13(18)11(6-9)14(19)20/h1-6,15-18H,7H2,(H,19,20)
PDB

UniProtKB/SwissProt

GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a



National Institutes of Health

Curated by ChEMBL


Assay Description
Inhibition of protein-tyrosine kinase p56lck


J Med Chem 36: 3015-20 (1993)


Article DOI: 10.1021/jm00072a023
BindingDB Entry DOI: 10.7270/Q2V123VX
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))
BDBM50046063
PNG
(5-(5,6-Dihydroxy-naphthalen-2-yl)-2-hydroxy-benzoi...)
Show SMILES OC(=O)c1cc(ccc1O)-c1ccc2c(O)c(O)ccc2c1
Show InChI InChI=1S/C17H12O5/c18-14-5-2-10(8-13(14)17(21)22)9-1-4-12-11(7-9)3-6-15(19)16(12)20/h1-8,18-20H,(H,21,22)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.20E+4n/an/an/an/an/an/a



National Institutes of Health

Curated by ChEMBL


Assay Description
Inhibition of protein-tyrosine kinase p56lck


J Med Chem 36: 3015-20 (1993)


Article DOI: 10.1021/jm00072a023
BindingDB Entry DOI: 10.7270/Q2V123VX
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))
BDBM50046060
PNG
(5-(5,8-Dihydroxy-naphthalen-2-yl)-2-hydroxy-benzoi...)
Show SMILES OC(=O)c1cc(ccc1O)-c1ccc2c(O)ccc(O)c2c1
Show InChI InChI=1S/C17H12O5/c18-14-5-6-15(19)12-7-9(1-3-11(12)14)10-2-4-16(20)13(8-10)17(21)22/h1-8,18-20H,(H,21,22)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.50E+4n/an/an/an/an/an/a



National Institutes of Health

Curated by ChEMBL


Assay Description
Inhibition of protein-tyrosine kinase p56lck


J Med Chem 36: 3015-20 (1993)


Article DOI: 10.1021/jm00072a023
BindingDB Entry DOI: 10.7270/Q2V123VX
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))
BDBM50046061
PNG
(5-(6,7-Dihydroxy-naphthalen-2-yl)-2-hydroxy-benzoi...)
Show SMILES OC(=O)c1cc(ccc1O)-c1ccc2cc(O)c(O)cc2c1
Show InChI InChI=1S/C17H12O5/c18-14-4-3-10(6-13(14)17(21)22)9-1-2-11-7-15(19)16(20)8-12(11)5-9/h1-8,18-20H,(H,21,22)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.50E+5n/an/an/an/an/an/a



National Institutes of Health

Curated by ChEMBL


Assay Description
Inhibition of protein-tyrosine kinase p56lck


J Med Chem 36: 3015-20 (1993)


Article DOI: 10.1021/jm00072a023
BindingDB Entry DOI: 10.7270/Q2V123VX
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))
BDBM50046062
PNG
(2-Hydroxy-5-naphthalen-2-yl-benzoic acid | CHEMBL1...)
Show SMILES OC(=O)c1cc(ccc1O)-c1ccc2ccccc2c1
Show InChI InChI=1S/C17H12O3/c18-16-8-7-14(10-15(16)17(19)20)13-6-5-11-3-1-2-4-12(11)9-13/h1-10,18H,(H,19,20)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a



National Institutes of Health

Curated by ChEMBL


Assay Description
Inhibition of protein-tyrosine kinase p56lck


J Med Chem 36: 3015-20 (1993)


Article DOI: 10.1021/jm00072a023
BindingDB Entry DOI: 10.7270/Q2V123VX
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%