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PubMed code 8496937

Compile data set for download or QSAR
Found 30 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Acetylcholinesterase


(Homo sapiens (Human))
BDBM50022775
PNG
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Show SMILES CN(C)C(=O)Oc1cccc(c1)[N+](C)(C)C
Show InChI InChI=1S/C12H19N2O2/c1-13(2)12(15)16-11-8-6-7-10(9-11)14(3,4)5/h6-9H,1-5H3/q+1
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PubMed
n/an/a 22n/an/an/an/an/an/a



Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of guinea pig acetylcholinesterase


J Med Chem 36: 572-9 (1993)


Article DOI: 10.1021/jm00057a007
BindingDB Entry DOI: 10.7270/Q2930TSP
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (Human))
BDBM50047730
PNG
(2-(1-{2-[(5-Piperidin-1-ylmethyl-furan-2-ylmethyl)...)
Show SMILES N#CC(C#N)C1=NCCN1CCNCc1ccc(CN2CCCCC2)o1
Show InChI InChI=1S/C19H26N6O/c20-12-16(13-21)19-23-7-11-25(19)10-6-22-14-17-4-5-18(26-17)15-24-8-2-1-3-9-24/h4-5,16,22H,1-3,6-11,14-15H2
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n/an/a 30n/an/an/an/an/an/a



Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of guinea pig acetylcholinesterase


J Med Chem 36: 572-9 (1993)


Article DOI: 10.1021/jm00057a007
BindingDB Entry DOI: 10.7270/Q2930TSP
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (Human))
BDBM50047736
PNG
(2-(1-{2-[(5-Piperidin-1-ylmethyl-furan-2-ylmethyl)...)
Show SMILES N#CC(C#N)c1nc2ccccc2n1CCNCc1ccc(CN2CCCCC2)o1
Show InChI InChI=1S/C23H26N6O/c24-14-18(15-25)23-27-21-6-2-3-7-22(21)29(23)13-10-26-16-19-8-9-20(30-19)17-28-11-4-1-5-12-28/h2-3,6-9,18,26H,1,4-5,10-13,16-17H2
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n/an/a 73n/an/an/an/an/an/a



Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of guinea pig acetylcholinesterase


J Med Chem 36: 572-9 (1993)


Article DOI: 10.1021/jm00057a007
BindingDB Entry DOI: 10.7270/Q2930TSP
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (Human))
BDBM50047745
PNG
(2-(1-{2-[(5-Pyrrolidin-1-ylmethyl-furan-2-ylmethyl...)
Show SMILES N#CC(C#N)C1=NCCN1CCNCc1ccc(CN2CCCC2)o1
Show InChI InChI=1S/C18H24N6O/c19-11-15(12-20)18-22-6-10-24(18)9-5-21-13-16-3-4-17(25-16)14-23-7-1-2-8-23/h3-4,15,21H,1-2,5-10,13-14H2
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n/an/a 80n/an/an/an/an/an/a



Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of guinea pig acetylcholinesterase


J Med Chem 36: 572-9 (1993)


Article DOI: 10.1021/jm00057a007
BindingDB Entry DOI: 10.7270/Q2930TSP
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (Human))
BDBM50368819
PNG
(CHEMBL1203534)
Show SMILES N#CC(C#N)C1=NCCN1CCNCc1ccc(CN2CCC=CC2)o1
Show InChI InChI=1S/C19H24N6O/c20-12-16(13-21)19-23-7-11-25(19)10-6-22-14-17-4-5-18(26-17)15-24-8-2-1-3-9-24/h1-2,4-5,16,22H,3,6-11,14-15H2
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n/an/a 95n/an/an/an/an/an/a



Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of guinea pig acetylcholinesterase


J Med Chem 36: 572-9 (1993)


Article DOI: 10.1021/jm00057a007
BindingDB Entry DOI: 10.7270/Q2930TSP
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (Human))
BDBM50368820
PNG
(CHEMBL1203538)
Show SMILES N#CC(C#N)C1=NCCN1CCNCc1ccc(CN2CCCCCC2)o1
Show InChI InChI=1S/C20H28N6O/c21-13-17(14-22)20-24-8-12-26(20)11-7-23-15-18-5-6-19(27-18)16-25-9-3-1-2-4-10-25/h5-6,17,23H,1-4,7-12,15-16H2
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n/an/a 120n/an/an/an/an/an/a



Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of guinea pig acetylcholinesterase


J Med Chem 36: 572-9 (1993)


Article DOI: 10.1021/jm00057a007
BindingDB Entry DOI: 10.7270/Q2930TSP
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (Human))
BDBM50047751
PNG
(2-(Methylamino-{2-[(5-pyrrolidin-1-ylmethyl-furan-...)
Show SMILES CN=C(NCCNCc1ccc(CN2CCCC2)o1)C(C#N)C#N
Show InChI InChI=1S/C17H24N6O/c1-20-17(14(10-18)11-19)22-7-6-21-12-15-4-5-16(24-15)13-23-8-2-3-9-23/h4-5,14,21H,2-3,6-9,12-13H2,1H3,(H,20,22)
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n/an/a 280n/an/an/an/an/an/a



Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of guinea pig acetylcholinesterase


J Med Chem 36: 572-9 (1993)


Article DOI: 10.1021/jm00057a007
BindingDB Entry DOI: 10.7270/Q2930TSP
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (Human))
BDBM50047747
PNG
(2-[1-(2-{[5-(4-Methyl-piperidin-1-ylmethyl)-furan-...)
Show SMILES CC1CCN(Cc2ccc(CNCCN3CCN=C3C(C#N)C#N)o2)CC1
Show InChI InChI=1S/C20H28N6O/c1-16-4-8-25(9-5-16)15-19-3-2-18(27-19)14-23-6-10-26-11-7-24-20(26)17(12-21)13-22/h2-3,16-17,23H,4-11,14-15H2,1H3
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n/an/a 290n/an/an/an/an/an/a



Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of guinea pig acetylcholinesterase


J Med Chem 36: 572-9 (1993)


Article DOI: 10.1021/jm00057a007
BindingDB Entry DOI: 10.7270/Q2930TSP
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (Human))
BDBM50047742
PNG
(2-[1-(2-{[5-(3-Methyl-piperidin-1-ylmethyl)-furan-...)
Show SMILES CC1CCCN(Cc2ccc(CNCCN3CCN=C3C(C#N)C#N)o2)C1
Show InChI InChI=1S/C20H28N6O/c1-16-3-2-8-25(14-16)15-19-5-4-18(27-19)13-23-6-9-26-10-7-24-20(26)17(11-21)12-22/h4-5,16-17,23H,2-3,6-10,13-15H2,1H3
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n/an/a 370n/an/an/an/an/an/a



Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of guinea pig acetylcholinesterase


J Med Chem 36: 572-9 (1993)


Article DOI: 10.1021/jm00057a007
BindingDB Entry DOI: 10.7270/Q2930TSP
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (Human))
BDBM50047731
PNG
(2-[1-(2-{[5-(3-Hydroxy-piperidin-1-ylmethyl)-furan...)
Show SMILES OC1CCCN(Cc2ccc(CNCCN3CCN=C3C(C#N)C#N)o2)C1
Show InChI InChI=1S/C19H26N6O2/c20-10-15(11-21)19-23-6-9-25(19)8-5-22-12-17-3-4-18(27-17)14-24-7-1-2-16(26)13-24/h3-4,15-16,22,26H,1-2,5-9,12-14H2
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n/an/a 370n/an/an/an/an/an/a



Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of guinea pig acetylcholinesterase


J Med Chem 36: 572-9 (1993)


Article DOI: 10.1021/jm00057a007
BindingDB Entry DOI: 10.7270/Q2930TSP
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (Human))
BDBM50047753
PNG
(2-(1-{2-[(5-Dimethylaminomethyl-furan-2-ylmethyl)-...)
Show SMILES CN(C)Cc1ccc(CNCCN2CCN=C2C(C#N)C#N)o1
Show InChI InChI=1S/C16H22N6O/c1-21(2)12-15-4-3-14(23-15)11-19-5-7-22-8-6-20-16(22)13(9-17)10-18/h3-4,13,19H,5-8,11-12H2,1-2H3
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n/an/a 390n/an/an/an/an/an/a



Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of guinea pig acetylcholinesterase


J Med Chem 36: 572-9 (1993)


Article DOI: 10.1021/jm00057a007
BindingDB Entry DOI: 10.7270/Q2930TSP
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (Human))
BDBM50047741
PNG
(2-[1-(2-{[5-(4-Hydroxy-piperidin-1-ylmethyl)-furan...)
Show SMILES OC1CCN(Cc2ccc(CNCCN3CCN=C3C(C#N)C#N)o2)CC1
Show InChI InChI=1S/C19H26N6O2/c20-11-15(12-21)19-23-6-10-25(19)9-5-22-13-17-1-2-18(27-17)14-24-7-3-16(26)4-8-24/h1-2,15-16,22,26H,3-10,13-14H2
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n/an/a 390n/an/an/an/an/an/a



Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of guinea pig acetylcholinesterase


J Med Chem 36: 572-9 (1993)


Article DOI: 10.1021/jm00057a007
BindingDB Entry DOI: 10.7270/Q2930TSP
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (Human))
BDBM50047752
PNG
(2-{1-[2-({5-[(Ethyl-methyl-amino)-methyl]-furan-2-...)
Show SMILES CCN(C)Cc1ccc(CNCCN2CCN=C2C(C#N)C#N)o1
Show InChI InChI=1S/C17H24N6O/c1-3-22(2)13-16-5-4-15(24-16)12-20-6-8-23-9-7-21-17(23)14(10-18)11-19/h4-5,14,20H,3,6-9,12-13H2,1-2H3
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n/an/a 430n/an/an/an/an/an/a



Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of guinea pig acetylcholinesterase


J Med Chem 36: 572-9 (1993)


Article DOI: 10.1021/jm00057a007
BindingDB Entry DOI: 10.7270/Q2930TSP
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (Human))
BDBM50047754
PNG
(2-[1-(2-{[5-(2-Methyl-piperidin-1-ylmethyl)-furan-...)
Show SMILES CC1CCCCN1Cc1ccc(CNCCN2CCN=C2C(C#N)C#N)o1
Show InChI InChI=1S/C20H28N6O/c1-16-4-2-3-9-26(16)15-19-6-5-18(27-19)14-23-7-10-25-11-8-24-20(25)17(12-21)13-22/h5-6,16-17,23H,2-4,7-11,14-15H2,1H3
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n/an/a 540n/an/an/an/an/an/a



Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of guinea pig acetylcholinesterase


J Med Chem 36: 572-9 (1993)


Article DOI: 10.1021/jm00057a007
BindingDB Entry DOI: 10.7270/Q2930TSP
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (Human))
BDBM50368818
PNG
(CHEMBL1203539)
Show SMILES CCN(CC)Cc1ccc(CNCCN2CCN=C2C(C#N)C#N)o1
Show InChI InChI=1S/C18H26N6O/c1-3-23(4-2)14-17-6-5-16(25-17)13-21-7-9-24-10-8-22-18(24)15(11-19)12-20/h5-6,15,21H,3-4,7-10,13-14H2,1-2H3
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n/an/a 600n/an/an/an/an/an/a



Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of guinea pig acetylcholinesterase


J Med Chem 36: 572-9 (1993)


Article DOI: 10.1021/jm00057a007
BindingDB Entry DOI: 10.7270/Q2930TSP
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (Human))
BDBM50047749
PNG
(2-({2-[(5-Dimethylaminomethyl-furan-2-ylmethyl)-am...)
Show SMILES CN=C(NCCNCc1ccc(CN(C)C)o1)C(C#N)C#N
Show InChI InChI=1S/C15H22N6O/c1-18-15(12(8-16)9-17)20-7-6-19-10-13-4-5-14(22-13)11-21(2)3/h4-5,12,19H,6-7,10-11H2,1-3H3,(H,18,20)
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n/an/a 630n/an/an/an/an/an/a



Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of guinea pig acetylcholinesterase


J Med Chem 36: 572-9 (1993)


Article DOI: 10.1021/jm00057a007
BindingDB Entry DOI: 10.7270/Q2930TSP
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (Human))
BDBM22893
PNG
(CHEMBL512 | Ranitidine | ZANTAC | dimethyl[(5-{[(2...)
Show SMILES CN\C([CH-][N+]([O-])=O)=[NH+]/CCSCc1ccc(CN(C)C)o1
Show InChI InChI=1S/C13H21N4O3S/c1-14-13(9-17(18)19)15-6-7-21-10-12-5-4-11(20-12)8-16(2)3/h4-5,9H,6-8,10H2,1-3H3,(H,14,15)/q-1/p+1
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n/an/a 650n/an/an/an/an/an/a



Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of guinea pig acetylcholinesterase


J Med Chem 36: 572-9 (1993)


Article DOI: 10.1021/jm00057a007
BindingDB Entry DOI: 10.7270/Q2930TSP
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (Human))
BDBM50368822
PNG
(CHEMBL1203537)
Show SMILES CN=C(NCCNCc1ccc(CN2CCCCC2)o1)C(C#N)C#N
Show InChI InChI=1S/C18H26N6O/c1-21-18(15(11-19)12-20)23-8-7-22-13-16-5-6-17(25-16)14-24-9-3-2-4-10-24/h5-6,15,22H,2-4,7-10,13-14H2,1H3,(H,21,23)
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n/an/a 830n/an/an/an/an/an/a



Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of guinea pig acetylcholinesterase


J Med Chem 36: 572-9 (1993)


Article DOI: 10.1021/jm00057a007
BindingDB Entry DOI: 10.7270/Q2930TSP
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (Human))
BDBM50047744
PNG
(1-{2-[(5-Piperidin-1-ylmethyl-furan-2-ylmethyl)-am...)
Show SMILES O=c1[nH]c2ccccc2n1CCNCc1ccc(CN2CCCCC2)o1
Show InChI InChI=1S/C20H26N4O2/c25-20-22-18-6-2-3-7-19(18)24(20)13-10-21-14-16-8-9-17(26-16)15-23-11-4-1-5-12-23/h2-3,6-9,21H,1,4-5,10-15H2,(H,22,25)
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n/an/a 1.20E+3n/an/an/an/an/an/a



Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of guinea pig acetylcholinesterase


J Med Chem 36: 572-9 (1993)


Article DOI: 10.1021/jm00057a007
BindingDB Entry DOI: 10.7270/Q2930TSP
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (Human))
BDBM50047737
PNG
(2-(1-{2-[(5-Thiomorpholin-4-ylmethyl-furan-2-ylmet...)
Show SMILES N#CC(C#N)C1=NCCN1CCNCc1ccc(CN2CCSCC2)o1
Show InChI InChI=1S/C18H24N6OS/c19-11-15(12-20)18-22-4-6-24(18)5-3-21-13-16-1-2-17(25-16)14-23-7-9-26-10-8-23/h1-2,15,21H,3-10,13-14H2
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n/an/a 1.50E+3n/an/an/an/an/an/a



Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of guinea pig acetylcholinesterase


J Med Chem 36: 572-9 (1993)


Article DOI: 10.1021/jm00057a007
BindingDB Entry DOI: 10.7270/Q2930TSP
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (Human))
BDBM50047732
PNG
((5-Dimethylaminomethyl-furan-2-ylmethyl)-[2-(2-nit...)
Show SMILES CN(C)Cc1ccc(CNCCN2CCN=C2C[N+]([O-])=O)o1
Show InChI InChI=1S/C14H23N5O3/c1-17(2)10-13-4-3-12(22-13)9-15-5-7-18-8-6-16-14(18)11-19(20)21/h3-4,15H,5-11H2,1-2H3
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n/an/a>2.00E+3n/an/an/an/an/an/a



Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of guinea pig acetylcholinesterase


J Med Chem 36: 572-9 (1993)


Article DOI: 10.1021/jm00057a007
BindingDB Entry DOI: 10.7270/Q2930TSP
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (Human))
BDBM50047733
PNG
(2-{[2-({5-[(Diisopropylamino)-methyl]-furan-2-ylme...)
Show SMILES CN=C(NCCNCc1ccc(CN(C(C)C)C(C)C)o1)C(C#N)C#N
Show InChI InChI=1S/C19H30N6O/c1-14(2)25(15(3)4)13-18-7-6-17(26-18)12-23-8-9-24-19(22-5)16(10-20)11-21/h6-7,14-16,23H,8-9,12-13H2,1-5H3,(H,22,24)
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PubMed
n/an/a 2.10E+3n/an/an/an/an/an/a



Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of guinea pig acetylcholinesterase


J Med Chem 36: 572-9 (1993)


Article DOI: 10.1021/jm00057a007
BindingDB Entry DOI: 10.7270/Q2930TSP
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (Human))
BDBM50047735
PNG
(4-Amino-5-chloro-N-{2-[(5-dimethylaminomethyl-fura...)
Show SMILES COc1cc(N)c(Cl)cc1C(=O)NCCNCc1ccc(CN(C)C)o1
Show InChI InChI=1S/C18H25ClN4O3/c1-23(2)11-13-5-4-12(26-13)10-21-6-7-22-18(24)14-8-15(19)16(20)9-17(14)25-3/h4-5,8-9,21H,6-7,10-11,20H2,1-3H3,(H,22,24)
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n/an/a 3.10E+3n/an/an/an/an/an/a



Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of guinea pig acetylcholinesterase


J Med Chem 36: 572-9 (1993)


Article DOI: 10.1021/jm00057a007
BindingDB Entry DOI: 10.7270/Q2930TSP
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (Human))
BDBM50368821
PNG
(CHEMBL1203535)
Show SMILES COC1CCCN(Cc2ccc(CNCCN3CCN=C3C(C#N)C#N)o2)C1
Show InChI InChI=1S/C20H28N6O2/c1-27-18-3-2-8-25(14-18)15-19-5-4-17(28-19)13-23-6-9-26-10-7-24-20(26)16(11-21)12-22/h4-5,16,18,23H,2-3,6-10,13-15H2,1H3
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n/an/a 3.30E+3n/an/an/an/an/an/a



Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of guinea pig acetylcholinesterase


J Med Chem 36: 572-9 (1993)


Article DOI: 10.1021/jm00057a007
BindingDB Entry DOI: 10.7270/Q2930TSP
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (Human))
BDBM50047748
PNG
(2-[1-(2-{[5-(2,6-Dimethyl-piperidin-1-ylmethyl)-fu...)
Show SMILES CC1CCCC(C)N1Cc1ccc(CNCCN2CCN=C2C(C#N)C#N)o1
Show InChI InChI=1S/C21H30N6O/c1-16-4-3-5-17(2)27(16)15-20-7-6-19(28-20)14-24-8-10-26-11-9-25-21(26)18(12-22)13-23/h6-7,16-18,24H,3-5,8-11,14-15H2,1-2H3
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n/an/a 4.50E+3n/an/an/an/an/an/a



Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of guinea pig acetylcholinesterase


J Med Chem 36: 572-9 (1993)


Article DOI: 10.1021/jm00057a007
BindingDB Entry DOI: 10.7270/Q2930TSP
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (Human))
BDBM50047739
PNG
(2-[1-(2-{[5-(4-Methyl-piperazin-1-ylmethyl)-furan-...)
Show SMILES CN1CCN(Cc2ccc(CNCCN3CCN=C3C(C#N)C#N)o2)CC1
Show InChI InChI=1S/C19H27N7O/c1-24-8-10-25(11-9-24)15-18-3-2-17(27-18)14-22-4-6-26-7-5-23-19(26)16(12-20)13-21/h2-3,16,22H,4-11,14-15H2,1H3
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n/an/a 4.50E+3n/an/an/an/an/an/a



Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of guinea pig acetylcholinesterase


J Med Chem 36: 572-9 (1993)


Article DOI: 10.1021/jm00057a007
BindingDB Entry DOI: 10.7270/Q2930TSP
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (Human))
BDBM50047740
PNG
(3-Methylamino-4-{2-[(5-piperidin-1-ylmethyl-furan-...)
Show SMILES CNc1c(NCCNCc2ccc(CN3CCCCC3)o2)c(=O)c1=O
Show InChI InChI=1S/C18H26N4O3/c1-19-15-16(18(24)17(15)23)21-8-7-20-11-13-5-6-14(25-13)12-22-9-3-2-4-10-22/h5-6,19-21H,2-4,7-12H2,1H3
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PubMed
n/an/a 9.30E+3n/an/an/an/an/an/a



Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of guinea pig acetylcholinesterase


J Med Chem 36: 572-9 (1993)


Article DOI: 10.1021/jm00057a007
BindingDB Entry DOI: 10.7270/Q2930TSP
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (Human))
BDBM50047734
PNG
(2-(1-{2-[(5-Morpholin-4-ylmethyl-furan-2-ylmethyl)...)
Show SMILES N#CC(C#N)C1=NCCN1CCNCc1ccc(CN2CCOCC2)o1
Show InChI InChI=1S/C18H24N6O2/c19-11-15(12-20)18-22-4-6-24(18)5-3-21-13-16-1-2-17(26-16)14-23-7-9-25-10-8-23/h1-2,15,21H,3-10,13-14H2
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n/an/a 1.10E+4n/an/an/an/an/an/a



Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of guinea pig acetylcholinesterase


J Med Chem 36: 572-9 (1993)


Article DOI: 10.1021/jm00057a007
BindingDB Entry DOI: 10.7270/Q2930TSP
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (Human))
BDBM48320
PNG
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Show SMILES CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC
Show InChI InChI=1S/C14H22ClN3O2/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3/h8-9H,4-7,16H2,1-3H3,(H,17,19)
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PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of guinea pig acetylcholinesterase


J Med Chem 36: 572-9 (1993)


Article DOI: 10.1021/jm00057a007
BindingDB Entry DOI: 10.7270/Q2930TSP
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (Human))
BDBM50047756
PNG
(2-({2-[(5-Methoxymethyl-furan-2-ylmethyl)-amino]-e...)
Show SMILES COCc1ccc(CNCCNC(=NC)C(C#N)C#N)o1
Show InChI InChI=1S/C14H19N5O2/c1-17-14(11(7-15)8-16)19-6-5-18-9-12-3-4-13(21-12)10-20-2/h3-4,11,18H,5-6,9-10H2,1-2H3,(H,17,19)
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PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of guinea pig acetylcholinesterase


J Med Chem 36: 572-9 (1993)


Article DOI: 10.1021/jm00057a007
BindingDB Entry DOI: 10.7270/Q2930TSP
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%