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PubMed code 8558530

Compile data set for download or QSAR
Found 4 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50048580
PNG
(CHEMBL29835 | Indol-1-yl-propyl-pyridin-4-yl-amine...)
Show SMILES CCCN(c1ccncc1)n1ccc2ccccc12
Show InChI InChI=1S/C16H17N3/c1-2-12-18(15-7-10-17-11-8-15)19-13-9-14-5-3-4-6-16(14)19/h3-11,13H,2,12H2,1H3
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Article
PubMed
n/an/a 1.30E+3n/an/an/an/an/an/a



Hoechst-Roussel Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Compound was tested for inhibition of [3H]-pirenzepine binding against Muscarinic acetylcholine receptor M1 from rat cortical membranes using in vitr...


J Med Chem 39: 582-7 (1996)


Article DOI: 10.1021/jm950644v
BindingDB Entry DOI: 10.7270/Q27080HJ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50048612
PNG
(CHEMBL350442 | Methyl-pyridin-4-yl-(2-vinyl-pyrrol...)
Show SMILES CN(c1ccncc1)n1cccc1C=C
Show InChI InChI=1S/C12H13N3/c1-3-11-5-4-10-15(11)14(2)12-6-8-13-9-7-12/h3-10H,1H2,2H3
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n/an/a 5.10E+3n/an/an/an/an/an/a



Hoechst-Roussel Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Compound was tested for inhibition of [3H]-pirenzepine binding against Muscarinic acetylcholine receptor M1 from rat cortical membranes using in vitr...


J Med Chem 39: 582-7 (1996)


Article DOI: 10.1021/jm950644v
BindingDB Entry DOI: 10.7270/Q27080HJ
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))
BDBM50048580
PNG
(CHEMBL29835 | Indol-1-yl-propyl-pyridin-4-yl-amine...)
Show SMILES CCCN(c1ccncc1)n1ccc2ccccc12
Show InChI InChI=1S/C16H17N3/c1-2-12-18(15-7-10-17-11-8-15)19-13-9-14-5-3-4-6-16(14)19/h3-11,13H,2,12H2,1H3
PDB
MMDB

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PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Hoechst-Roussel Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Compound was tested in vitro for the inhibition of Acetylcholinesterase from rat striatum


J Med Chem 39: 582-7 (1996)


Article DOI: 10.1021/jm950644v
BindingDB Entry DOI: 10.7270/Q27080HJ
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))
BDBM50048612
PNG
(CHEMBL350442 | Methyl-pyridin-4-yl-(2-vinyl-pyrrol...)
Show SMILES CN(c1ccncc1)n1cccc1C=C
Show InChI InChI=1S/C12H13N3/c1-3-11-5-4-10-15(11)14(2)12-6-8-13-9-7-12/h3-10H,1H2,2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Hoechst-Roussel Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Compound was tested in vitro for the inhibition of Acetylcholinesterase from rat striatum


J Med Chem 39: 582-7 (1996)


Article DOI: 10.1021/jm950644v
BindingDB Entry DOI: 10.7270/Q27080HJ
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%