Compile Data Set for Download or QSAR
maximum 50k data
Found 34 Enz. Inhib. hit(s) with all data for entry = 50006423
TargetTumor necrosis factor(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50048929(4-(7-Methyl-2,6-dioxo-3-propyl-2,3,6,7-tetrahydro-...)
Affinity DataIC50:  5.00E+3nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50048928(4-(2,4-Dioxo-1-propyl-1,4-dihydro-2H-pteridin-3-yl...)
Affinity DataIC50:  5.00E+3nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50048933(4-(3,7-Dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-purin...)
Affinity DataIC50:  6.00E+3nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50048931(3-(3,7-Dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-purin...)
Affinity DataIC50:  1.00E+4nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50048924(5-(3,7-Dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-purin...)
Affinity DataIC50:  1.10E+4nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50048943(4-(1-Methyl-2,4-dioxo-1,4-dihydro-2H-pteridin-3-yl...)
Affinity DataIC50:  1.20E+4nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)
Affinity DataIC50:  1.20E+4nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50048925(4-(1-Butyl-2,4-dioxo-1,4-dihydro-2H-pteridin-3-yl)...)
Affinity DataIC50:  1.50E+4nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50048932(4-(2,4-Dioxo-1-pentyl-1,4-dihydro-2H-pteridin-3-yl...)
Affinity DataIC50:  1.60E+4nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50048935(4-(5,7-Dioxo-4-propyl-4,5-dihydro-7H-[1,2,5]thiadi...)
Affinity DataIC50:  1.80E+4nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50048920(4-[2,4-Dioxo-1-(tetrahydro-furan-3-yl)-1,4-dihydro...)
Affinity DataIC50:  1.90E+4nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50048948(4-(1-Isobutyl-2,4-dioxo-1,4-dihydro-2H-pteridin-3-...)
Affinity DataIC50:  2.00E+4nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50048942(4-(4-Methyl-5,7-dioxo-4,5-dihydro-7H-[1,2,5]thiadi...)
Affinity DataIC50:  2.50E+4nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50048938((Z)-4-(1-Methyl-2,4-dioxo-1,4-dihydro-2H-pteridin-...)
Affinity DataIC50:  2.50E+4nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50048940(1-Hexyl-8-hydroxy-3-methyl-3,7,8,9-tetrahydro-puri...)
Affinity DataIC50:  5.00E+4nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50010981((Ro 20-1724)4-(3-Butoxy-4-methoxy-benzyl)-imidazol...)
Affinity DataIC50:  5.00E+4nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50048939(4-(1-Methyl-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-...)
Affinity DataIC50:  5.50E+4nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50048921(4-(8-Bromo-3,7-dimethyl-2,6-dioxo-2,3,6,7-tetrahyd...)
Affinity DataIC50:  6.00E+4nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50048927(6-Heptyl-4-methyl-4H-[1,2,5]thiadiazolo[3,4-d]pyri...)
Affinity DataIC50:  7.50E+4nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM10850(1-(5-Oxohexyl)theobromine (pentoxifylline) | 3,7-d...)
Affinity DataIC50:  8.50E+4nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50048945(4-(8-Mercapto-3,7-dimethyl-2,6-dioxo-2,3,6,7-tetra...)
Affinity DataIC50:  1.00E+5nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50048922(4-(6,7-Diethyl-1-methyl-2,4-dioxo-1,4-dihydro-2H-p...)
Affinity DataIC50:  1.30E+5nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50048934(4-(1-Benzyl-2,4-dioxo-1,4-dihydro-2H-pteridin-3-yl...)
Affinity DataIC50:  1.75E+5nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50048923(4-(1-Methyl-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-...)
Affinity DataIC50: >2.00E+5nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50048944(4-(1-Methyl-2,4-dioxo-1,4-dihydro-2H-pteridin-3-yl...)
Affinity DataIC50: >2.00E+5nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50048950(4-(8-Mercapto-3,7-dimethyl-2,6-dioxo-2,3,6,7-tetra...)
Affinity DataIC50: >2.00E+5nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50048949(4-(1-Methyl-2,4-dioxo-6-phenyl-1,4-dihydro-2H-pter...)
Affinity DataIC50: >2.00E+5nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50048947(4-(2,4-Dioxo-1-propyl-1,4-dihydro-2H-pteridin-3-yl...)
Affinity DataIC50: >2.00E+5nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50048946(4-(4-Methyl-5,7-dioxo-4,5-dihydro-7H-[1,2,5]thiadi...)
Affinity DataIC50: >2.00E+5nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50048941((3,7-Dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-purin-1...)
Affinity DataIC50:  2.00E+5nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50048926(8-Mercapto-3-methyl-3,7-dihydro-purine-2,6-dione |...)
Affinity DataIC50: >2.00E+5nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50048937(4-(3,7-Dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-purin...)
Affinity DataIC50: >2.00E+5nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50048936(1-[4-Carboxypropyl]-3,7-Dimethylxanthine (Metaboli...)
Affinity DataIC50: >2.00E+5nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50048930(4-(8-Bromo-3,7-dimethyl-2,6-dioxo-2,3,6,7-tetrahyd...)
Affinity DataIC50: >2.00E+5nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed