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PubMed code 8568830

Compile data set for download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Human immunodeficiency virus type 1 integrase


(Human immunodeficiency virus 1)
BDBM50049177
PNG
((3R,4R)-3,4-Bis-(3,4-dihydroxy-benzyl)-dihydro-fur...)
Show SMILES Oc1ccc(C[C@H]2COC(=O)[C@@H]2Cc2ccc(O)c(O)c2)cc1O
Show InChI InChI=1S/C18H18O6/c19-14-3-1-10(7-16(14)21)5-12-9-24-18(23)13(12)6-11-2-4-15(20)17(22)8-11/h1-4,7-8,12-13,19-22H,5-6,9H2/t12-,13+/m0/s1
PDB
MMDB

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.40E+3n/an/an/an/an/an/a



Freie Universität Berlin

Curated by ChEMBL


Assay Description
Inhibitory concentration of the compound against Strand transfer by HIV -1 Integrase


J Med Chem 39: 86-95 (1996)


Article DOI: 10.1021/jm950387u
BindingDB Entry DOI: 10.7270/Q2RR1XB2
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 integrase


(Human immunodeficiency virus 1)
BDBM50049177
PNG
((3R,4R)-3,4-Bis-(3,4-dihydroxy-benzyl)-dihydro-fur...)
Show SMILES Oc1ccc(C[C@H]2COC(=O)[C@@H]2Cc2ccc(O)c(O)c2)cc1O
Show InChI InChI=1S/C18H18O6/c19-14-3-1-10(7-16(14)21)5-12-9-24-18(23)13(12)6-11-2-4-15(20)17(22)8-11/h1-4,7-8,12-13,19-22H,5-6,9H2/t12-,13+/m0/s1
PDB
MMDB

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.14E+4n/an/an/an/an/an/a



Freie Universität Berlin

Curated by ChEMBL


Assay Description
Inhibitory concentration of the compound against 3'-processing by HIV -1 Integrase


J Med Chem 39: 86-95 (1996)


Article DOI: 10.1021/jm950387u
BindingDB Entry DOI: 10.7270/Q2RR1XB2
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%