Compile Data Set for Download or QSAR
maximum 50k data
Found 34 Enz. Inhib. hit(s) with all data for entry = 50006453
TargetThymidylate synthase(Mus musculus)
Zeneca Pharma

Curated by ChEMBL
LigandPNGBDBM50049291(2-{4-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6-ylm...)
Affinity DataIC50:  10nMAssay Description:In vitro inhibitory activity against thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharma

Curated by ChEMBL
LigandPNGBDBM50049286(2-{4-[(2-Aminomethyl-4-oxo-3,4-dihydro-quinazolin-...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibitory activity against thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharma

Curated by ChEMBL
LigandPNGBDBM50049276(2-(2-Fluoro-4-{methyl-[7-methyl-2-(4-methyl-pipera...)
Affinity DataIC50:  28nMAssay Description:In vitro inhibitory activity against thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharma

Curated by ChEMBL
LigandPNGBDBM50033910(4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazolin-6-yl...)
Affinity DataIC50:  44nMAssay Description:In vitro inhibitory activity against thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharma

Curated by ChEMBL
LigandPNGBDBM50012244(2-{4-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6-ylm...)
Affinity DataIC50:  50nMAssay Description:In vitro inhibitory activity against thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharma

Curated by ChEMBL
LigandPNGBDBM50049267(4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazolin-6-yl...)
Affinity DataIC50:  56nMAssay Description:In vitro inhibitory activity against thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharma

Curated by ChEMBL
LigandPNGBDBM50049288(2-Fluoro-4-[(2-hydroxymethyl-7-methyl-4-oxo-3,4-di...)
Affinity DataIC50:  72nMAssay Description:In vitro inhibitory activity against thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharma

Curated by ChEMBL
LigandPNGBDBM50049266(2-Fluoro-4-[(2-hydroxymethyl-7-methyl-4-oxo-3,4-di...)
Affinity DataIC50:  80nMAssay Description:In vitro inhibitory activity against thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharma

Curated by ChEMBL
LigandPNGBDBM50049281(4-[(2-Dimethylaminomethyl-7-methyl-4-oxo-3,4-dihyd...)
Affinity DataIC50:  84nMAssay Description:In vitro inhibitory activity against thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharma

Curated by ChEMBL
LigandPNGBDBM50049273(2-{4-[(2-Hydroxymethyl-4-oxo-3,4-dihydro-quinazoli...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibitory activity against thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharma

Curated by ChEMBL
LigandPNGBDBM50049261(2-Fluoro-4-[(7-methyl-2-morpholin-4-ylmethyl-4-oxo...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibitory activity against thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharma

Curated by ChEMBL
LigandPNGBDBM50033932(4-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmeth...)
Affinity DataIC50:  110nMAssay Description:In vitro inhibitory activity against thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharma

Curated by ChEMBL
LigandPNGBDBM50049283(2-Fluoro-4-{[7-methyl-4-oxo-2-(pyrimidin-2-ylsulfa...)
Affinity DataIC50:  110nMAssay Description:In vitro inhibitory activity against thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharma

Curated by ChEMBL
LigandPNGBDBM50049272(2-Fluoro-4-{[7-methyl-2-(4-methyl-piperazin-1-ylme...)
Affinity DataIC50:  110nMAssay Description:In vitro inhibitory activity against thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharma

Curated by ChEMBL
LigandPNGBDBM50049270(4-[(2-Dimethylaminomethyl-7-methyl-4-oxo-3,4-dihyd...)
Affinity DataIC50:  140nMAssay Description:In vitro inhibitory activity against thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharma

Curated by ChEMBL
LigandPNGBDBM50049269(4-[(2-{[Bis-(2-hydroxy-ethyl)-amino]-methyl}-7-met...)
Affinity DataIC50:  160nMAssay Description:In vitro inhibitory activity against thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharma

Curated by ChEMBL
LigandPNGBDBM50049279(4-{[2-(Methanesulfonylamino-methyl)-4-oxo-3,4-dihy...)
Affinity DataIC50:  180nMAssay Description:In vitro inhibitory activity against thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharma

Curated by ChEMBL
LigandPNGBDBM50049263(4-[(2-{[(2-Dimethylamino-ethyl)-methyl-amino]-meth...)
Affinity DataIC50:  200nMAssay Description:In vitro inhibitory activity against thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharma

Curated by ChEMBL
LigandPNGBDBM50049277(2-(4-{[4-Oxo-2-(pyrimidin-2-ylsulfanylmethyl)-3,4-...)
Affinity DataIC50:  240nMAssay Description:In vitro inhibitory activity against thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharma

Curated by ChEMBL
LigandPNGBDBM50049282(4-[(2-Hydroxymethyl-4-oxo-3,4-dihydro-quinazolin-6...)
Affinity DataIC50:  300nMAssay Description:In vitro inhibitory activity against thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharma

Curated by ChEMBL
LigandPNGBDBM50049280(4-[(2-Cyanomethyl-4-oxo-3,4-dihydro-quinazolin-6-y...)
Affinity DataIC50:  380nMAssay Description:In vitro inhibitory activity against thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharma

Curated by ChEMBL
LigandPNGBDBM50049290(4-[(2-Morpholin-4-ylmethyl-4-oxo-3,4-dihydro-quina...)
Affinity DataIC50:  380nMAssay Description:In vitro inhibitory activity against thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharma

Curated by ChEMBL
LigandPNGBDBM50049287(CHEMBL159633 | N-(3-Nitro-benzyl)-4-{[4-oxo-2-(pyr...)
Affinity DataIC50:  480nMAssay Description:In vitro inhibitory activity against thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharma

Curated by ChEMBL
LigandPNGBDBM50049265(4-{[2-(3-Hydroxy-pyrrolidin-1-ylmethyl)-4-oxo-3,4-...)
Affinity DataIC50:  600nMAssay Description:In vitro inhibitory activity against thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharma

Curated by ChEMBL
LigandPNGBDBM50049274(4-[(2-Dimethylaminomethyl-4-oxo-3,4-dihydro-quinaz...)
Affinity DataIC50:  620nMAssay Description:In vitro inhibitory activity against thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharma

Curated by ChEMBL
LigandPNGBDBM50049271(4-{[2-(2-Methoxy-ethoxymethyl)-4-oxo-3,4-dihydro-q...)
Affinity DataIC50:  640nMAssay Description:In vitro inhibitory activity against thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharma

Curated by ChEMBL
LigandPNGBDBM50049289(4-[(2-{[(2-Dimethylamino-ethyl)-methyl-amino]-meth...)
Affinity DataIC50:  820nMAssay Description:In vitro inhibitory activity against thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharma

Curated by ChEMBL
LigandPNGBDBM50049284(4-{[2-(4-Amino-pyrimidin-2-ylsulfanylmethyl)-4-oxo...)
Affinity DataIC50:  840nMAssay Description:In vitro inhibitory activity against thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharma

Curated by ChEMBL
LigandPNGBDBM50049285(4-{[2-(4-Methyl-piperazin-1-ylmethyl)-4-oxo-3,4-di...)
Affinity DataIC50:  900nMAssay Description:In vitro inhibitory activity against thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharma

Curated by ChEMBL
LigandPNGBDBM50049275(4-{[2-(4-Amino-6-hydroxy-pyrimidin-2-ylsulfanylmet...)
Affinity DataIC50:  1.04E+3nMAssay Description:In vitro inhibitory activity against thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharma

Curated by ChEMBL
LigandPNGBDBM50049262(4-[(2-Chloromethyl-4-oxo-3,4-dihydro-quinazolin-6-...)
Affinity DataIC50:  1.21E+3nMAssay Description:In vitro inhibitory activity against thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharma

Curated by ChEMBL
LigandPNGBDBM50049268(4-[(2-Aminomethyl-4-oxo-3,4-dihydro-quinazolin-6-y...)
Affinity DataIC50: >1.70E+3nMAssay Description:In vitro inhibitory activity against thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharma

Curated by ChEMBL
LigandPNGBDBM50049278(4-{[2-(4-Hydroxy-pyrimidin-2-ylsulfanylmethyl)-4-o...)
Affinity DataIC50:  3.30E+3nMAssay Description:In vitro inhibitory activity against thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Zeneca Pharma

Curated by ChEMBL
LigandPNGBDBM50049264(4-[(2-Methylaminomethyl-4-oxo-3,4-dihydro-quinazol...)
Affinity DataIC50:  4.20E+3nMAssay Description:In vitro inhibitory activity against thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed