BindingDB logo
myBDB logout

PubMed code 8627606

Compile data set for download or QSAR
Found 60 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3604
PNG
(4-N-(3-bromophenyl)-6-N,6-N-dimethylpyrido[3,4-d]p...)
Show SMILES CN(C)c1cc2c(Nc3cccc(Br)c3)ncnc2cn1
Show InChI InChI=1S/C15H14BrN5/c1-21(2)14-7-12-13(8-17-14)18-9-19-15(12)20-11-5-3-4-10(16)6-11/h3-9H,1-2H3,(H,18,19,20)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 0.00600n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3603
PNG
(4-N-(3-bromophenyl)-6-N-methylpyrido[3,4-d]pyrimid...)
Show SMILES CNc1cc2c(Nc3cccc(Br)c3)ncnc2cn1
Show InChI InChI=1S/C14H12BrN5/c1-16-13-6-11-12(7-17-13)18-8-19-14(11)20-10-4-2-3-9(15)5-10/h2-8H,1H3,(H,16,17)(H,18,19,20)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 0.00800n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3032
PNG
(CHEMBL1204168 | CHEMBL29197 | N-(3-bromophenyl)-6,...)
Show SMILES COc1cc2ncnc(Nc3cccc(Br)c3)c2cc1OC
Show InChI InChI=1S/C16H14BrN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h3-9H,1-2H3,(H,18,19,20)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 0.0290n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of Epidermal growth factor receptor from human A431 cell membranes


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3032
PNG
(CHEMBL1204168 | CHEMBL29197 | N-(3-bromophenyl)-6,...)
Show SMILES COc1cc2ncnc(Nc3cccc(Br)c3)c2cc1OC
Show InChI InChI=1S/C16H14BrN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h3-9H,1-2H3,(H,18,19,20)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 0.0290n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3595
PNG
(4-N-(3-bromophenyl)-7-N,7-N-dimethylpyrido[4,3-d]p...)
Show SMILES CN(C)c1cc2ncnc(Nc3cccc(Br)c3)c2cn1
Show InChI InChI=1S/C15H14BrN5/c1-21(2)14-7-13-12(8-17-14)15(19-9-18-13)20-11-5-3-4-10(16)6-11/h3-9H,1-2H3,(H,18,19,20)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 0.0910n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50049566
PNG
(CHEMBL55729 | Quinazolin-7-ylamine)
Show SMILES Nc1ccc2cncnc2c1
Show InChI InChI=1S/C8H7N3/c9-7-2-1-6-4-10-5-11-8(6)3-7/h1-5H,9H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 0.100n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3594
PNG
(4-N-(3-bromophenyl)-7-N-methylpyrido[4,3-d]pyrimid...)
Show SMILES CNc1cc2ncnc(Nc3cccc(Br)c3)c2cn1
Show InChI InChI=1S/C14H12BrN5/c1-16-13-6-12-11(7-17-13)14(19-8-18-12)20-10-4-2-3-9(15)5-10/h2-8H,1H3,(H,16,17)(H,18,19,20)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 0.130n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3600
PNG
(4-N-(3-bromophenyl)pyrido[3,4-d]pyrimidine-4,6-dia...)
Show SMILES Nc1cc2c(Nc3cccc(Br)c3)ncnc2cn1
Show InChI InChI=1S/C13H10BrN5/c14-8-2-1-3-9(4-8)19-13-10-5-12(15)16-6-11(10)17-7-18-13/h1-7H,(H2,15,16)(H,17,18,19)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 0.130n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50049567
PNG
(CHEMBL53300 | Quinazolin-6-ylamine)
Show SMILES Nc1ccc2ncncc2c1
Show InChI InChI=1S/C8H7N3/c9-7-1-2-8-6(3-7)4-10-5-11-8/h1-5H,9H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 0.790n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3606
PNG
(4-N-(3-bromophenyl)-6-N-[(4-methoxyphenyl)methyl]p...)
Show SMILES COc1ccc(CNc2cc3c(Nc4cccc(Br)c4)ncnc3cn2)cc1
Show InChI InChI=1S/C21H18BrN5O/c1-28-17-7-5-14(6-8-17)11-23-20-10-18-19(12-24-20)25-13-26-21(18)27-16-4-2-3-15(22)9-16/h2-10,12-13H,11H2,1H3,(H,23,24)(H,25,26,27)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 2.30n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3605
PNG
(4-[(3-bromophenyl)amino]-6-methoxypyrido[3,4-d]pyr...)
Show SMILES COc1cc2c(Nc3cccc(Br)c3)ncnc2cn1
Show InChI InChI=1S/C14H11BrN4O/c1-20-13-6-11-12(7-16-13)17-8-18-14(11)19-10-4-2-3-9(15)5-10/h2-8H,1H3,(H,17,18,19)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 2.60n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3620
PNG
(4-N-(3-bromophenyl)-6-N-methylpyrido[3,2-d]pyrimid...)
Show SMILES CNc1ccc2ncnc(Nc3cccc(Br)c3)c2n1
Show InChI InChI=1S/C14H12BrN5/c1-16-12-6-5-11-13(20-12)14(18-8-17-11)19-10-4-2-3-9(15)7-10/h2-8H,1H3,(H,16,20)(H,17,18,19)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 3.10n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50049571
PNG
(CHEMBL52882 | {4-[(Z)-3-Bromo-phenylimino]-3-methy...)
Show SMILES CNC1=NC=C2C(C1)N=CN(C)C2=Nc1cccc(Br)c1
Show InChI InChI=1S/C15H16BrN5/c1-17-14-7-13-12(8-18-14)15(21(2)9-19-13)20-11-5-3-4-10(16)6-11/h3-6,8-9,13H,7H2,1-2H3,(H,17,18)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.10n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50049565
PNG
(CHEMBL295961 | Methyl-quinazolin-7-yl-amine)
Show SMILES CNc1ccc2cncnc2c1
Show InChI InChI=1S/C9H9N3/c1-10-8-3-2-7-5-11-6-12-9(7)4-8/h2-6,10H,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3622
PNG
(4-[(3-bromophenyl)amino]-6-methoxypyrido[3,2-d]pyr...)
Show SMILES COc1ccc2ncnc(Nc3cccc(Br)c3)c2n1
Show InChI InChI=1S/C14H11BrN4O/c1-20-12-6-5-11-13(19-12)14(17-8-16-11)18-10-4-2-3-9(15)7-10/h2-8H,1H3,(H,16,17,18)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 4.30n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50049570
PNG
(CHEMBL53850 | Methyl-quinazolin-6-yl-amine)
Show SMILES CNc1ccc2ncncc2c1
Show InChI InChI=1S/C9H9N3/c1-10-8-2-3-9-7(4-8)5-11-6-12-9/h2-6,10H,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 7n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3617
PNG
(4-N-(3-bromophenyl)pyrido[3,2-d]pyrimidine-4,6-dia...)
Show SMILES Nc1ccc2ncnc(Nc3cccc(Br)c3)c2n1
Show InChI InChI=1S/C13H10BrN5/c14-8-2-1-3-9(6-8)18-13-12-10(16-7-17-13)4-5-11(15)19-12/h1-7H,(H2,15,19)(H,16,17,18)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 7.60n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3607
PNG
(6-(Methylamino)-4-(phenylamino)pyrido[3,4-d]pyrimi...)
Show SMILES CNc1cc2c(Nc3ccccc3)ncnc2cn1
Show InChI InChI=1S/C14H13N5/c1-15-13-7-11-12(8-16-13)17-9-18-14(11)19-10-5-3-2-4-6-10/h2-9H,1H3,(H,15,16)(H,17,18,19)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 9n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3621
PNG
(4-N-(3-bromophenyl)-6-N,6-N-dimethylpyrido[3,2-d]p...)
Show SMILES CN(C)c1ccc2ncnc(Nc3cccc(Br)c3)c2n1
Show InChI InChI=1S/C15H14BrN5/c1-21(2)13-7-6-12-14(20-13)15(18-9-17-12)19-11-5-3-4-10(16)8-11/h3-9H,1-2H3,(H,17,18,19)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 9.60n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50049568
PNG
(7-Methoxy-quinazoline | CHEMBL300491)
Show SMILES COc1ccc2cncnc2c1
Show InChI InChI=1S/C9H8N2O/c1-12-8-3-2-7-5-10-6-11-9(7)4-8/h2-6H,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 10n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3608
PNG
(4-[(Phenylmethyl)amino]-pyrido[2,3-d]pyrimidine | ...)
Show SMILES C(Nc1ncnc2ncccc12)c1ccccc1
Show InChI InChI=1S/C14H12N4/c1-2-5-11(6-3-1)9-16-14-12-7-4-8-15-13(12)17-10-18-14/h1-8,10H,9H2,(H,15,16,17,18)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>10n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3309
PNG
(4-N-(3-bromophenyl)pyrido[4,3-d]pyrimidine-4,7-dia...)
Show SMILES Nc1cc2ncnc(Nc3cccc(Br)c3)c2cn1
Show InChI InChI=1S/C13H10BrN5/c14-8-2-1-3-9(4-8)19-13-10-6-16-12(15)5-11(10)17-7-18-13/h1-7H,(H2,15,16)(H,17,18,19)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 10n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50049574
PNG
(CHEMBL52784 | Dimethyl-quinazolin-7-yl-amine)
Show SMILES CN(C)c1ccc2cncnc2c1
Show InChI InChI=1S/C10H11N3/c1-13(2)9-4-3-8-6-11-7-12-10(8)5-9/h3-7H,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 11n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3605
PNG
(4-[(3-bromophenyl)amino]-6-methoxypyrido[3,4-d]pyr...)
Show SMILES COc1cc2c(Nc3cccc(Br)c3)ncnc2cn1
Show InChI InChI=1S/C14H11BrN4O/c1-20-13-6-11-12(7-16-13)17-8-18-14(11)19-10-4-2-3-9(15)5-10/h2-8H,1H3,(H,17,18,19)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 12n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of Epidermal growth factor receptor autophosphorylation in A431 human epidermoid carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3593
PNG
(4-[(3-Bromophenyl)amino]-7-fluoropyrido[4,3-d]pyri...)
Show SMILES Fc1cc2ncnc(Nc3cccc(Br)c3)c2cn1
Show InChI InChI=1S/C13H8BrFN4/c14-8-2-1-3-9(4-8)19-13-10-6-16-12(15)5-11(10)17-7-18-13/h1-7H,(H,17,18,19)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 13n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3595
PNG
(4-N-(3-bromophenyl)-7-N,7-N-dimethylpyrido[4,3-d]p...)
Show SMILES CN(C)c1cc2ncnc(Nc3cccc(Br)c3)c2cn1
Show InChI InChI=1S/C15H14BrN5/c1-21(2)14-7-13-12(8-17-14)15(19-9-18-13)20-11-5-3-4-10(16)6-11/h3-9H,1-2H3,(H,18,19,20)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 14n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of Epidermal growth factor receptor autophosphorylation in A431 human epidermoid carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3603
PNG
(4-N-(3-bromophenyl)-6-N-methylpyrido[3,4-d]pyrimid...)
Show SMILES CNc1cc2c(Nc3cccc(Br)c3)ncnc2cn1
Show InChI InChI=1S/C14H12BrN5/c1-16-13-6-11-12(7-17-13)18-8-19-14(11)20-10-4-2-3-9(15)5-10/h2-8H,1H3,(H,16,17)(H,18,19,20)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 15n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of Epidermal growth factor receptor autophosphorylation in A431 human epidermoid carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3594
PNG
(4-N-(3-bromophenyl)-7-N-methylpyrido[4,3-d]pyrimid...)
Show SMILES CNc1cc2ncnc(Nc3cccc(Br)c3)c2cn1
Show InChI InChI=1S/C14H12BrN5/c1-16-13-6-12-11(7-17-13)14(19-8-18-12)20-10-4-2-3-9(15)5-10/h2-8H,1H3,(H,16,17)(H,18,19,20)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 16n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of Epidermal growth factor receptor autophosphorylation in A431 human epidermoid carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3600
PNG
(4-N-(3-bromophenyl)pyrido[3,4-d]pyrimidine-4,6-dia...)
Show SMILES Nc1cc2c(Nc3cccc(Br)c3)ncnc2cn1
Show InChI InChI=1S/C13H10BrN5/c14-8-2-1-3-9(4-8)19-13-10-5-12(15)16-6-11(10)17-7-18-13/h1-7H,(H2,15,16)(H,17,18,19)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 16n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of Epidermal growth factor receptor autophosphorylation in A431 human epidermoid carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3618
PNG
(4-[(3-Bromophenyl)amino]-6-chloropyrido[3,2-d]pyri...)
Show SMILES Clc1ccc2ncnc(Nc3cccc(Br)c3)c2n1
Show InChI InChI=1S/C13H8BrClN4/c14-8-2-1-3-9(6-8)18-13-12-10(16-7-17-13)4-5-11(15)19-12/h1-7H,(H,16,17,18)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 18n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3620
PNG
(4-N-(3-bromophenyl)-6-N-methylpyrido[3,2-d]pyrimid...)
Show SMILES CNc1ccc2ncnc(Nc3cccc(Br)c3)c2n1
Show InChI InChI=1S/C14H12BrN5/c1-16-12-6-5-11-13(20-12)14(18-8-17-11)19-10-4-2-3-9(15)7-10/h2-8H,1H3,(H,16,20)(H,17,18,19)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 20n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of Epidermal growth factor receptor autophosphorylation in A431 human epidermoid carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3604
PNG
(4-N-(3-bromophenyl)-6-N,6-N-dimethylpyrido[3,4-d]p...)
Show SMILES CN(C)c1cc2c(Nc3cccc(Br)c3)ncnc2cn1
Show InChI InChI=1S/C15H14BrN5/c1-21(2)14-7-12-13(8-17-14)18-9-19-15(12)20-11-5-3-4-10(16)6-11/h3-9H,1-2H3,(H,18,19,20)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 21n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of Epidermal growth factor receptor autophosphorylation in A431 human epidermoid carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50049572
PNG
(1,3-benzodiazine | 1,3-diazanaphthalene | 5,6-benz...)
Show SMILES c1ccc2ncncc2c1
Show InChI InChI=1S/C8H6N2/c1-2-4-8-7(3-1)5-9-6-10-8/h1-6H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
Purchase

CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem

Patents

Article
PubMed
n/an/a 27n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3592
PNG
(7-Acetamido-4-[(3-bromophenyl)amino]pyrido[4,3-d]-...)
Show SMILES CC(=O)Nc1cc2ncnc(Nc3cccc(Br)c3)c2cn1
Show InChI InChI=1S/C15H12BrN5O/c1-9(22)20-14-6-13-12(7-17-14)15(19-8-18-13)21-11-4-2-3-10(16)5-11/h2-8H,1H3,(H,17,20,22)(H,18,19,21)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 29n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50049573
PNG
(6-Methoxy-quinazoline | CHEMBL52472)
Show SMILES COc1ccc2ncncc2c1
Show InChI InChI=1S/C9H8N2O/c1-12-8-2-3-9-7(4-8)5-10-6-11-9/h2-6H,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 30n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3621
PNG
(4-N-(3-bromophenyl)-6-N,6-N-dimethylpyrido[3,2-d]p...)
Show SMILES CN(C)c1ccc2ncnc(Nc3cccc(Br)c3)c2n1
Show InChI InChI=1S/C15H14BrN5/c1-21(2)13-7-6-12-14(20-13)15(18-9-17-12)19-11-5-3-4-10(16)8-11/h3-9H,1-2H3,(H,17,18,19)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 32n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of Epidermal growth factor receptor autophosphorylation in A431 human epidermoid carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3616
PNG
(4-[(3-Bromophenyl)-amino]pyrido[3,2-d]pyrimidine |...)
Show SMILES Brc1cccc(Nc2ncnc3cccnc23)c1
Show InChI InChI=1S/C13H9BrN4/c14-9-3-1-4-10(7-9)18-13-12-11(16-8-17-13)5-2-6-15-12/h1-8H,(H,16,17,18)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 34n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3590
PNG
(4-[(3-Bromophenyl)-amino]pyrido[4,3-d]pyrimidine |...)
Show SMILES Brc1cccc(Nc2ncnc3ccncc23)c1
Show InChI InChI=1S/C13H9BrN4/c14-9-2-1-3-10(6-9)18-13-11-7-15-5-4-12(11)16-8-17-13/h1-8H,(H,16,17,18)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 35n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3596
PNG
(4-[(3-Bromophenyl)amino]-7-methoxypyrido[4,3-d]pyr...)
Show SMILES COc1cc2ncnc(Nc3cccc(Br)c3)c2cn1
Show InChI InChI=1S/C14H11BrN4O/c1-20-13-6-12-11(7-16-13)14(18-8-17-12)19-10-4-2-3-9(15)5-10/h2-8H,1H3,(H,17,18,19)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 39n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3601
PNG
(4-[(3-Bromophenyl)amino]-6-chloropyrido[3,4-d]pyri...)
Show SMILES Clc1cc2c(Nc3cccc(Br)c3)ncnc2cn1
Show InChI InChI=1S/C13H8BrClN4/c14-8-2-1-3-9(4-8)19-13-10-5-12(15)16-6-11(10)17-7-18-13/h1-7H,(H,17,18,19)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 40n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3619
PNG
(4-[(3-bromophenyl)-amino]-6-fluoropyrido[3,2-d]pyr...)
Show SMILES Fc1ccc2ncnc(Nc3cccc(Br)c3)c2n1
Show InChI InChI=1S/C13H8BrFN4/c14-8-2-1-3-9(6-8)18-13-12-10(16-7-17-13)4-5-11(15)19-12/h1-7H,(H,16,17,18)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 44n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3599
PNG
(4-[(3-Bromophenyl)-amino]pyrido[3,4-d]pyrimidine |...)
Show SMILES Brc1cccc(Nc2ncnc3cnccc23)c1
Show InChI InChI=1S/C13H9BrN4/c14-9-2-1-3-10(6-9)18-13-11-4-5-15-7-12(11)16-8-17-13/h1-8H,(H,16,17,18)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 51n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3612
PNG
(4-N-(3-bromophenyl)-7-N-methylpyrido[2,3-d]pyrimid...)
Show SMILES CNc1ccc2c(Nc3cccc(Br)c3)ncnc2n1
Show InChI InChI=1S/C14H12BrN5/c1-16-12-6-5-11-13(17-8-18-14(11)20-12)19-10-4-2-3-9(15)7-10/h2-8H,1H3,(H2,16,17,18,19,20)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 52n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3617
PNG
(4-N-(3-bromophenyl)pyrido[3,2-d]pyrimidine-4,6-dia...)
Show SMILES Nc1ccc2ncnc(Nc3cccc(Br)c3)c2n1
Show InChI InChI=1S/C13H10BrN5/c14-8-2-1-3-9(6-8)18-13-12-10(16-7-17-13)4-5-11(15)19-12/h1-7H,(H2,15,19)(H,16,17,18)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 53n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of Epidermal growth factor receptor autophosphorylation in A431 human epidermoid carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3589
PNG
(7-Acetamido-4-[(phenylmethyl)amino]pyrido[4,3-d]py...)
Show SMILES CC(=O)Nc1cc2ncnc(NCc3ccccc3)c2cn1
Show InChI InChI=1S/C16H15N5O/c1-11(22)21-15-7-14-13(9-17-15)16(20-10-19-14)18-8-12-5-3-2-4-6-12/h2-7,9-10H,8H2,1H3,(H,17,21,22)(H,18,19,20)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 100n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3309
PNG
(4-N-(3-bromophenyl)pyrido[4,3-d]pyrimidine-4,7-dia...)
Show SMILES Nc1cc2ncnc(Nc3cccc(Br)c3)c2cn1
Show InChI InChI=1S/C13H10BrN5/c14-8-2-1-3-9(4-8)19-13-10-6-16-12(15)5-11(10)17-7-18-13/h1-7H,(H2,15,16)(H,17,18,19)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 110n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of Epidermal growth factor receptor autophosphorylation in A431 human epidermoid carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50049569
PNG
(CHEMBL55150 | Dimethyl-quinazolin-6-yl-amine)
Show SMILES CN(C)c1ccc2ncncc2c1
Show InChI InChI=1S/C10H11N3/c1-13(2)9-3-4-10-8(5-9)6-11-7-12-10/h3-7H,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 120n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3602
PNG
(4-[(3-Bromophenyl)amino]-6-fluoropyrido[3,4-d]pyri...)
Show SMILES Fc1cc2c(Nc3cccc(Br)c3)ncnc2cn1
Show InChI InChI=1S/C13H8BrFN4/c14-8-2-1-3-9(4-8)19-13-10-5-12(15)16-6-11(10)17-7-18-13/h1-7H,(H,17,18,19)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 124n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3614
PNG
(4-[(3-bromophenyl)amino]-7-methoxypyrido[2,3-d]pyr...)
Show SMILES COc1ccc2c(Nc3cccc(Br)c3)ncnc2n1
Show InChI InChI=1S/C14H11BrN4O/c1-20-12-6-5-11-13(16-8-17-14(11)19-12)18-10-4-2-3-9(15)7-10/h2-8H,1H3,(H,16,17,18,19)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 263n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3613
PNG
(4-N-(3-bromophenyl)-7-N,7-N-dimethylpyrido[2,3-d]p...)
Show SMILES CN(C)c1ccc2c(Nc3cccc(Br)c3)ncnc2n1
Show InChI InChI=1S/C15H14BrN5/c1-21(2)13-7-6-12-14(17-9-18-15(12)20-13)19-11-5-3-4-10(16)8-11/h3-9H,1-2H3,(H,17,18,19,20)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 324n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3612
PNG
(4-N-(3-bromophenyl)-7-N-methylpyrido[2,3-d]pyrimid...)
Show SMILES CNc1ccc2c(Nc3cccc(Br)c3)ncnc2n1
Show InChI InChI=1S/C14H12BrN5/c1-16-12-6-5-11-13(17-8-18-14(11)20-12)19-10-4-2-3-9(15)7-10/h2-8H,1H3,(H2,16,17,18,19,20)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 552n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of Epidermal growth factor receptor autophosphorylation in A431 human epidermoid carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3331
PNG
(4-N-benzylpyrido[4,3-d]pyrimidine-4,7-diamine | 7-...)
Show SMILES Nc1cc2ncnc(NCc3ccccc3)c2cn1
Show InChI InChI=1S/C14H13N5/c15-13-6-12-11(8-16-13)14(19-9-18-12)17-7-10-4-2-1-3-5-10/h1-6,8-9H,7H2,(H2,15,16)(H,17,18,19)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 578n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3615
PNG
(4-[(Phenylmethyl)amino]-pyrido[3,2-d]pyrimidine | ...)
Show SMILES C(Nc1ncnc2cccnc12)c1ccccc1
Show InChI InChI=1S/C14H12N4/c1-2-5-11(6-3-1)9-16-14-13-12(17-10-18-14)7-4-8-15-13/h1-8,10H,9H2,(H,16,17,18)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 603n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3611
PNG
(4-[(3-Bromophenyl)amino]-7-fluoropyrido[2,3-d]pyri...)
Show SMILES Fc1ccc2c(Nc3cccc(Br)c3)ncnc2n1
Show InChI InChI=1S/C13H8BrFN4/c14-8-2-1-3-9(6-8)18-12-10-4-5-11(15)19-13(10)17-7-16-12/h1-7H,(H,16,17,18,19)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 684n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3609
PNG
(4-[(3-bromophenyl)-amino]pyrido[2,3-d]pyrimidine |...)
Show SMILES Brc1cccc(Nc2ncnc3ncccc23)c1
Show InChI InChI=1S/C13H9BrN4/c14-9-3-1-4-10(7-9)18-13-11-5-2-6-15-12(11)16-8-17-13/h1-8H,(H,15,16,17,18)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 688n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3610
PNG
(4-N-(3-bromophenyl)pyrido[2,3-d]pyrimidine-4,7-dia...)
Show SMILES Nc1ccc2c(Nc3cccc(Br)c3)ncnc2n1
Show InChI InChI=1S/C13H10BrN5/c14-8-2-1-3-9(6-8)18-12-10-4-5-11(15)19-13(10)17-7-16-12/h1-7H,(H3,15,16,17,18,19)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 940n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3587
PNG
(4-[(Phenylmethyl)amino]-pyrido[4,3-d]pyrimidine | ...)
Show SMILES C(Nc1ncnc2ccncc12)c1ccccc1
Show InChI InChI=1S/C14H12N4/c1-2-4-11(5-3-1)8-16-14-12-9-15-7-6-13(12)17-10-18-14/h1-7,9-10H,8H2,(H,16,17,18)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.46E+3n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3598
PNG
(4-[(Phenylmethyl)amino]-pyrido[3,4-d]pyrimidine | ...)
Show SMILES C(Nc1ncnc2cnccc12)c1ccccc1
Show InChI InChI=1S/C14H12N4/c1-2-4-11(5-3-1)8-16-14-12-6-7-15-9-13(12)17-10-18-14/h1-7,9-10H,8H2,(H,16,17,18)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 2.03E+3n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3331
PNG
(4-N-benzylpyrido[4,3-d]pyrimidine-4,7-diamine | 7-...)
Show SMILES Nc1cc2ncnc(NCc3ccccc3)c2cn1
Show InChI InChI=1S/C14H13N5/c15-13-6-12-11(8-16-13)14(19-9-18-12)17-7-10-4-2-1-3-5-10/h1-6,8-9H,7H2,(H2,15,16)(H,17,18,19)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 2.09E+3n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of Epidermal growth factor receptor autophosphorylation in A431 human epidermoid carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3613
PNG
(4-N-(3-bromophenyl)-7-N,7-N-dimethylpyrido[2,3-d]p...)
Show SMILES CN(C)c1ccc2c(Nc3cccc(Br)c3)ncnc2n1
Show InChI InChI=1S/C15H14BrN5/c1-21(2)13-7-6-12-14(17-9-18-15(12)20-13)19-11-5-3-4-10(16)8-11/h3-9H,1-2H3,(H,17,18,19,20)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 2.30E+3n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of Epidermal growth factor receptor autophosphorylation in A431 human epidermoid carcinoma cells


J Med Chem 39: 1823-35 (1996)


Article DOI: 10.1021/jm9508651
BindingDB Entry DOI: 10.7270/Q26T0KPR
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%