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PubMed code 8632408

Compile data set for download or QSAR
Found 24 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50454480
PNG
(CHEMBL2093059)
Show SMILES CN(c1nn[nH]n1)c1cccc(NC(=O)N[C@@H]2N=C(C3CCCCC3)c3ccccc3N(C)C2=O)c1
Show InChI InChI=1S/C25H29N9O2/c1-33(24-29-31-32-30-24)18-12-8-11-17(15-18)26-25(36)28-22-23(35)34(2)20-14-7-6-13-19(20)21(27-22)16-9-4-3-5-10-16/h6-8,11-16,22H,3-5,9-10H2,1-2H3,(H2,26,28,36)(H,29,30,31,32)/t22-/m0/s1
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n/an/a 0.0540n/an/an/an/an/an/a



Neuroscience Research Centre

Curated by ChEMBL


Assay Description
Inhibition of [125 I]BH CCK-8S binding to Cholecystokinin type B receptor in guinea pig cortical membranes


J Med Chem 39: 842-9 (1996)


Article DOI: 10.1021/jm9506736
BindingDB Entry DOI: 10.7270/Q25T3JJC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50454481
PNG
(CHEMBL2110201)
Show SMILES CN1c2ccccc2C(=N[C@@H](NC(=O)Nc2ccc(C)c(Nc3nn[nH]n3)c2)C1=O)C1CCCCC1
Show InChI InChI=1S/C25H29N9O2/c1-15-12-13-17(14-19(15)27-24-30-32-33-31-24)26-25(36)29-22-23(35)34(2)20-11-7-6-10-18(20)21(28-22)16-8-4-3-5-9-16/h6-7,10-14,16,22H,3-5,8-9H2,1-2H3,(H2,26,29,36)(H2,27,30,31,32,33)/t22-/m0/s1
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n/an/a 0.0740n/an/an/an/an/an/a



Neuroscience Research Centre

Curated by ChEMBL


Assay Description
Inhibition of [125 I]BH CCK-8S binding to Cholecystokinin type B receptor in guinea pig cortical membranes


J Med Chem 39: 842-9 (1996)


Article DOI: 10.1021/jm9506736
BindingDB Entry DOI: 10.7270/Q25T3JJC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50049783
PNG
(1-((R)-1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benz...)
Show SMILES CN1c2ccccc2C(=N[C@@H](NC(=O)Nc2ccc3CCN(c4nnn[nH]4)c3c2)C1=O)c1ccccc1
Show InChI InChI=1S/C26H23N9O2/c1-34-20-10-6-5-9-19(20)22(17-7-3-2-4-8-17)28-23(24(34)36)29-26(37)27-18-12-11-16-13-14-35(21(16)15-18)25-30-32-33-31-25/h2-12,15,23H,13-14H2,1H3,(H2,27,29,37)(H,30,31,32,33)/t23-/m0/s1
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n/an/a 0.110n/an/an/an/an/an/a



Neuroscience Research Centre

Curated by ChEMBL


Assay Description
Inhibition of [125 I]BH CCK-8S binding to Cholecystokinin type B receptor in guinea pig cortical membranes


J Med Chem 39: 842-9 (1996)


Article DOI: 10.1021/jm9506736
BindingDB Entry DOI: 10.7270/Q25T3JJC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50049789
PNG
(1-((R)-5-Cyclohexyl-1-methyl-2-oxo-2,3-dihydro-1H-...)
Show SMILES CN1c2ccccc2C(=N[C@@H](NC(=O)Nc2cccc(Nc3nnn[nH]3)c2)C1=O)C1CCCCC1
Show InChI InChI=1S/C24H27N9O2/c1-33-19-13-6-5-12-18(19)20(15-8-3-2-4-9-15)27-21(22(33)34)28-24(35)26-17-11-7-10-16(14-17)25-23-29-31-32-30-23/h5-7,10-15,21H,2-4,8-9H2,1H3,(H2,26,28,35)(H2,25,29,30,31,32)/t21-/m0/s1
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n/an/a 0.200n/an/an/an/an/an/a



Neuroscience Research Centre

Curated by ChEMBL


Assay Description
Inhibition of [125 I]BH CCK-8S binding to Cholecystokinin type B receptor in guinea pig cortical membranes


J Med Chem 39: 842-9 (1996)


Article DOI: 10.1021/jm9506736
BindingDB Entry DOI: 10.7270/Q25T3JJC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50454482
PNG
(CHEMBL2110202)
Show SMILES CN1c2ccccc2C(=N[C@@H](NC(=O)Nc2cccc(CNc3nn[nH]n3)c2)C1=O)C1CCCCC1
Show InChI InChI=1S/C25H29N9O2/c1-34-20-13-6-5-12-19(20)21(17-9-3-2-4-10-17)28-22(23(34)35)29-25(36)27-18-11-7-8-16(14-18)15-26-24-30-32-33-31-24/h5-8,11-14,17,22H,2-4,9-10,15H2,1H3,(H2,27,29,36)(H2,26,30,31,32,33)/t22-/m0/s1
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n/an/a 0.280n/an/an/an/an/an/a



Neuroscience Research Centre

Curated by ChEMBL


Assay Description
Inhibition of [125 I]BH CCK-8S binding to Cholecystokinin type B receptor in guinea pig cortical membranes


J Med Chem 39: 842-9 (1996)


Article DOI: 10.1021/jm9506736
BindingDB Entry DOI: 10.7270/Q25T3JJC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50049785
PNG
(1-((R)-5-Cyclohexyl-1-methyl-2-oxo-2,3-dihydro-1H-...)
Show SMILES CN(c1nnn[nH]1)c1cc(NC(=O)N[C@@H]2N=C(C3CCCCC3)c3ccccc3N(C)C2=O)ccc1C
Show InChI InChI=1S/C26H31N9O2/c1-16-13-14-18(15-21(16)35(3)25-30-32-33-31-25)27-26(37)29-23-24(36)34(2)20-12-8-7-11-19(20)22(28-23)17-9-5-4-6-10-17/h7-8,11-15,17,23H,4-6,9-10H2,1-3H3,(H2,27,29,37)(H,30,31,32,33)/t23-/m0/s1
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n/an/a 0.300n/an/an/an/an/an/a



Neuroscience Research Centre

Curated by ChEMBL


Assay Description
Inhibition of [125 I]BH CCK-8S binding to Cholecystokinin type B receptor in guinea pig cortical membranes


J Med Chem 39: 842-9 (1996)


Article DOI: 10.1021/jm9506736
BindingDB Entry DOI: 10.7270/Q25T3JJC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50049786
PNG
(1-((R)-1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benz...)
Show SMILES CN(c1nnn[nH]1)c1cccc(NC(=O)N[C@@H]2N=C(c3ccccc3)c3ccccc3N(C)C2=O)c1
Show InChI InChI=1S/C25H23N9O2/c1-33(24-29-31-32-30-24)18-12-8-11-17(15-18)26-25(36)28-22-23(35)34(2)20-14-7-6-13-19(20)21(27-22)16-9-4-3-5-10-16/h3-15,22H,1-2H3,(H2,26,28,36)(H,29,30,31,32)/t22-/m0/s1
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n/an/a 0.580n/an/an/an/an/an/a



Neuroscience Research Centre

Curated by ChEMBL


Assay Description
Inhibition of [125 I]BH CCK-8S binding to Cholecystokinin type B receptor in guinea pig cortical membranes


J Med Chem 39: 842-9 (1996)


Article DOI: 10.1021/jm9506736
BindingDB Entry DOI: 10.7270/Q25T3JJC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50049788
PNG
(1-((R)-1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benz...)
Show SMILES CN1c2ccccc2C(=N[C@@H](NC(=O)Nc2ccc(C)c(Nc3nnn[nH]3)c2)C1=O)c1ccccc1
Show InChI InChI=1S/C25H23N9O2/c1-15-12-13-17(14-19(15)27-24-30-32-33-31-24)26-25(36)29-22-23(35)34(2)20-11-7-6-10-18(20)21(28-22)16-8-4-3-5-9-16/h3-14,22H,1-2H3,(H2,26,29,36)(H2,27,30,31,32,33)/t22-/m0/s1
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n/an/a 1.10n/an/an/an/an/an/a



Neuroscience Research Centre

Curated by ChEMBL


Assay Description
Inhibition of [125 I]BH CCK-8S binding to Cholecystokinin type B receptor in guinea pig cortical membranes


J Med Chem 39: 842-9 (1996)


Article DOI: 10.1021/jm9506736
BindingDB Entry DOI: 10.7270/Q25T3JJC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50049790
PNG
(1-((R)-1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benz...)
Show SMILES CN1c2ccccc2C(=N[C@@H](NC(=O)Nc2cccc(Nc3nnn[nH]3)c2)C1=O)c1ccccc1
Show InChI InChI=1S/C24H21N9O2/c1-33-19-13-6-5-12-18(19)20(15-8-3-2-4-9-15)27-21(22(33)34)28-24(35)26-17-11-7-10-16(14-17)25-23-29-31-32-30-23/h2-14,21H,1H3,(H2,26,28,35)(H2,25,29,30,31,32)/t21-/m0/s1
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n/an/a 5.70n/an/an/an/an/an/a



Neuroscience Research Centre

Curated by ChEMBL


Assay Description
Inhibition of [125 I]BH CCK-8S binding to Cholecystokinin type B receptor in guinea pig cortical membranes


J Med Chem 39: 842-9 (1996)


Article DOI: 10.1021/jm9506736
BindingDB Entry DOI: 10.7270/Q25T3JJC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50049784
PNG
(1-((R)-1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benz...)
Show SMILES CN1c2ccccc2C(=N[C@@H](NC(=O)Nc2cccc(CNc3nnn[nH]3)c2)C1=O)c1ccccc1
Show InChI InChI=1S/C25H23N9O2/c1-34-20-13-6-5-12-19(20)21(17-9-3-2-4-10-17)28-22(23(34)35)29-25(36)27-18-11-7-8-16(14-18)15-26-24-30-32-33-31-24/h2-14,22H,15H2,1H3,(H2,27,29,36)(H2,26,30,31,32,33)/t22-/m0/s1
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n/an/a 7.5n/an/an/an/an/an/a



Neuroscience Research Centre

Curated by ChEMBL


Assay Description
Inhibition of [125 I]BH CCK-8S binding to Cholecystokinin type B receptor in guinea pig cortical membranes


J Med Chem 39: 842-9 (1996)


Article DOI: 10.1021/jm9506736
BindingDB Entry DOI: 10.7270/Q25T3JJC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50006878
PNG
((R)-1-(1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benz...)
Show SMILES CN1c2ccccc2C(=N[C@@H](NC(=O)Nc2ccc(C)cc2)C1=O)c1ccccc1
Show InChI InChI=1S/C24H22N4O2/c1-16-12-14-18(15-13-16)25-24(30)27-22-23(29)28(2)20-11-7-6-10-19(20)21(26-22)17-8-4-3-5-9-17/h3-15,22H,1-2H3,(H2,25,27,30)/t22-/m0/s1
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n/an/a 8.5n/an/an/an/an/an/a



Neuroscience Research Centre

Curated by ChEMBL


Assay Description
Inhibition of [125 I]BH CCK-8S binding to Cholecystokinin type B receptor in guinea pig cortical membranes


J Med Chem 39: 842-9 (1996)


Article DOI: 10.1021/jm9506736
BindingDB Entry DOI: 10.7270/Q25T3JJC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50049787
PNG
(1-{4-Methyl-3-[methyl-(1H-tetrazol-5-yl)-amino]-ph...)
Show SMILES CN(c1nnn[nH]1)c1cc(NC(=O)N[C@@H]2N=C(c3ccccc3)c3ccccc3N(C)C2=O)ccc1C
Show InChI InChI=1S/C26H25N9O2/c1-16-13-14-18(15-21(16)35(3)25-30-32-33-31-25)27-26(37)29-23-24(36)34(2)20-12-8-7-11-19(20)22(28-23)17-9-5-4-6-10-17/h4-15,23H,1-3H3,(H2,27,29,37)(H,30,31,32,33)/t23-/m0/s1
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n/an/a 20n/an/an/an/an/an/a



Neuroscience Research Centre

Curated by ChEMBL


Assay Description
Inhibition of [125 I]BH CCK-8S binding to Cholecystokinin type B receptor in guinea pig cortical membranes


J Med Chem 39: 842-9 (1996)


Article DOI: 10.1021/jm9506736
BindingDB Entry DOI: 10.7270/Q25T3JJC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50454482
PNG
(CHEMBL2110202)
Show SMILES CN1c2ccccc2C(=N[C@@H](NC(=O)Nc2cccc(CNc3nn[nH]n3)c2)C1=O)C1CCCCC1
Show InChI InChI=1S/C25H29N9O2/c1-34-20-13-6-5-12-19(20)21(17-9-3-2-4-10-17)28-22(23(34)35)29-25(36)27-18-11-7-8-16(14-18)15-26-24-30-32-33-31-24/h5-8,11-14,17,22H,2-4,9-10,15H2,1H3,(H2,27,29,36)(H2,26,30,31,32,33)/t22-/m0/s1
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n/an/a 153n/an/an/an/an/an/a



Neuroscience Research Centre

Curated by ChEMBL


Assay Description
Inhibition of [125 I]BH CCK-8S binding to Cholecystokinin type A receptor in pancreatic tissue


J Med Chem 39: 842-9 (1996)


Article DOI: 10.1021/jm9506736
BindingDB Entry DOI: 10.7270/Q25T3JJC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50049789
PNG
(1-((R)-5-Cyclohexyl-1-methyl-2-oxo-2,3-dihydro-1H-...)
Show SMILES CN1c2ccccc2C(=N[C@@H](NC(=O)Nc2cccc(Nc3nnn[nH]3)c2)C1=O)C1CCCCC1
Show InChI InChI=1S/C24H27N9O2/c1-33-19-13-6-5-12-18(19)20(15-8-3-2-4-9-15)27-21(22(33)34)28-24(35)26-17-11-7-10-16(14-17)25-23-29-31-32-30-23/h5-7,10-15,21H,2-4,8-9H2,1H3,(H2,26,28,35)(H2,25,29,30,31,32)/t21-/m0/s1
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n/an/a 200n/an/an/an/an/an/a



Neuroscience Research Centre

Curated by ChEMBL


Assay Description
Inhibition of [125 I]BH CCK-8S binding to Cholecystokinin type A receptor in pancreatic tissue


J Med Chem 39: 842-9 (1996)


Article DOI: 10.1021/jm9506736
BindingDB Entry DOI: 10.7270/Q25T3JJC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50454480
PNG
(CHEMBL2093059)
Show SMILES CN(c1nn[nH]n1)c1cccc(NC(=O)N[C@@H]2N=C(C3CCCCC3)c3ccccc3N(C)C2=O)c1
Show InChI InChI=1S/C25H29N9O2/c1-33(24-29-31-32-30-24)18-12-8-11-17(15-18)26-25(36)28-22-23(35)34(2)20-14-7-6-13-19(20)21(27-22)16-9-4-3-5-10-16/h6-8,11-16,22H,3-5,9-10H2,1-2H3,(H2,26,28,36)(H,29,30,31,32)/t22-/m0/s1
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n/an/a 400n/an/an/an/an/an/a



Neuroscience Research Centre

Curated by ChEMBL


Assay Description
Inhibition of [125 I]BH CCK-8S binding to Cholecystokinin type A receptor in pancreatic tissue


J Med Chem 39: 842-9 (1996)


Article DOI: 10.1021/jm9506736
BindingDB Entry DOI: 10.7270/Q25T3JJC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50006878
PNG
((R)-1-(1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benz...)
Show SMILES CN1c2ccccc2C(=N[C@@H](NC(=O)Nc2ccc(C)cc2)C1=O)c1ccccc1
Show InChI InChI=1S/C24H22N4O2/c1-16-12-14-18(15-13-16)25-24(30)27-22-23(29)28(2)20-11-7-6-10-19(20)21(26-22)17-8-4-3-5-9-17/h3-15,22H,1-2H3,(H2,25,27,30)/t22-/m0/s1
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n/an/a 736n/an/an/an/an/an/a



Neuroscience Research Centre

Curated by ChEMBL


Assay Description
Inhibition of [125 I]BH CCK-8S binding to Cholecystokinin type A receptor in pancreatic tissue


J Med Chem 39: 842-9 (1996)


Article DOI: 10.1021/jm9506736
BindingDB Entry DOI: 10.7270/Q25T3JJC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50454481
PNG
(CHEMBL2110201)
Show SMILES CN1c2ccccc2C(=N[C@@H](NC(=O)Nc2ccc(C)c(Nc3nn[nH]n3)c2)C1=O)C1CCCCC1
Show InChI InChI=1S/C25H29N9O2/c1-15-12-13-17(14-19(15)27-24-30-32-33-31-24)26-25(36)29-22-23(35)34(2)20-11-7-6-10-18(20)21(28-22)16-8-4-3-5-9-16/h6-7,10-14,16,22H,3-5,8-9H2,1-2H3,(H2,26,29,36)(H2,27,30,31,32,33)/t22-/m0/s1
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n/an/a 802n/an/an/an/an/an/a



Neuroscience Research Centre

Curated by ChEMBL


Assay Description
Inhibition of [125 I]BH CCK-8S binding to Cholecystokinin type A receptor in pancreatic tissue


J Med Chem 39: 842-9 (1996)


Article DOI: 10.1021/jm9506736
BindingDB Entry DOI: 10.7270/Q25T3JJC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50049785
PNG
(1-((R)-5-Cyclohexyl-1-methyl-2-oxo-2,3-dihydro-1H-...)
Show SMILES CN(c1nnn[nH]1)c1cc(NC(=O)N[C@@H]2N=C(C3CCCCC3)c3ccccc3N(C)C2=O)ccc1C
Show InChI InChI=1S/C26H31N9O2/c1-16-13-14-18(15-21(16)35(3)25-30-32-33-31-25)27-26(37)29-23-24(36)34(2)20-12-8-7-11-19(20)22(28-23)17-9-5-4-6-10-17/h7-8,11-15,17,23H,4-6,9-10H2,1-3H3,(H2,27,29,37)(H,30,31,32,33)/t23-/m0/s1
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n/an/a 1.60E+3n/an/an/an/an/an/a



Neuroscience Research Centre

Curated by ChEMBL


Assay Description
Inhibition of [125 I]BH CCK-8S binding to Cholecystokinin type A receptor in pancreatic tissue


J Med Chem 39: 842-9 (1996)


Article DOI: 10.1021/jm9506736
BindingDB Entry DOI: 10.7270/Q25T3JJC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50049784
PNG
(1-((R)-1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benz...)
Show SMILES CN1c2ccccc2C(=N[C@@H](NC(=O)Nc2cccc(CNc3nnn[nH]3)c2)C1=O)c1ccccc1
Show InChI InChI=1S/C25H23N9O2/c1-34-20-13-6-5-12-19(20)21(17-9-3-2-4-10-17)28-22(23(34)35)29-25(36)27-18-11-7-8-16(14-18)15-26-24-30-32-33-31-24/h2-14,22H,15H2,1H3,(H2,27,29,36)(H2,26,30,31,32,33)/t22-/m0/s1
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n/an/a 3.00E+3n/an/an/an/an/an/a



Neuroscience Research Centre

Curated by ChEMBL


Assay Description
Inhibition of [125 I]BH CCK-8S binding to Cholecystokinin type A receptor in pancreatic tissue


J Med Chem 39: 842-9 (1996)


Article DOI: 10.1021/jm9506736
BindingDB Entry DOI: 10.7270/Q25T3JJC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50049790
PNG
(1-((R)-1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benz...)
Show SMILES CN1c2ccccc2C(=N[C@@H](NC(=O)Nc2cccc(Nc3nnn[nH]3)c2)C1=O)c1ccccc1
Show InChI InChI=1S/C24H21N9O2/c1-33-19-13-6-5-12-18(19)20(15-8-3-2-4-9-15)27-21(22(33)34)28-24(35)26-17-11-7-10-16(14-17)25-23-29-31-32-30-23/h2-14,21H,1H3,(H2,26,28,35)(H2,25,29,30,31,32)/t21-/m0/s1
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n/an/a 3.00E+3n/an/an/an/an/an/a



Neuroscience Research Centre

Curated by ChEMBL


Assay Description
Inhibition of [125 I]BH CCK-8S binding to Cholecystokinin type A receptor in pancreatic tissue


J Med Chem 39: 842-9 (1996)


Article DOI: 10.1021/jm9506736
BindingDB Entry DOI: 10.7270/Q25T3JJC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50049786
PNG
(1-((R)-1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benz...)
Show SMILES CN(c1nnn[nH]1)c1cccc(NC(=O)N[C@@H]2N=C(c3ccccc3)c3ccccc3N(C)C2=O)c1
Show InChI InChI=1S/C25H23N9O2/c1-33(24-29-31-32-30-24)18-12-8-11-17(15-18)26-25(36)28-22-23(35)34(2)20-14-7-6-13-19(20)21(27-22)16-9-4-3-5-10-16/h3-15,22H,1-2H3,(H2,26,28,36)(H,29,30,31,32)/t22-/m0/s1
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n/an/a 3.00E+3n/an/an/an/an/an/a



Neuroscience Research Centre

Curated by ChEMBL


Assay Description
Inhibition of [125 I]BH CCK-8S binding to Cholecystokinin type A receptor in pancreatic tissue


J Med Chem 39: 842-9 (1996)


Article DOI: 10.1021/jm9506736
BindingDB Entry DOI: 10.7270/Q25T3JJC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50049788
PNG
(1-((R)-1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benz...)
Show SMILES CN1c2ccccc2C(=N[C@@H](NC(=O)Nc2ccc(C)c(Nc3nnn[nH]3)c2)C1=O)c1ccccc1
Show InChI InChI=1S/C25H23N9O2/c1-15-12-13-17(14-19(15)27-24-30-32-33-31-24)26-25(36)29-22-23(35)34(2)20-11-7-6-10-18(20)21(28-22)16-8-4-3-5-9-16/h3-14,22H,1-2H3,(H2,26,29,36)(H2,27,30,31,32,33)/t22-/m0/s1
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n/an/a 3.00E+3n/an/an/an/an/an/a



Neuroscience Research Centre

Curated by ChEMBL


Assay Description
Inhibition of [125 I]BH CCK-8S binding to Cholecystokinin type A receptor in pancreatic tissue


J Med Chem 39: 842-9 (1996)


Article DOI: 10.1021/jm9506736
BindingDB Entry DOI: 10.7270/Q25T3JJC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50049787
PNG
(1-{4-Methyl-3-[methyl-(1H-tetrazol-5-yl)-amino]-ph...)
Show SMILES CN(c1nnn[nH]1)c1cc(NC(=O)N[C@@H]2N=C(c3ccccc3)c3ccccc3N(C)C2=O)ccc1C
Show InChI InChI=1S/C26H25N9O2/c1-16-13-14-18(15-21(16)35(3)25-30-32-33-31-25)27-26(37)29-23-24(36)34(2)20-12-8-7-11-19(20)22(28-23)17-9-5-4-6-10-17/h4-15,23H,1-3H3,(H2,27,29,37)(H,30,31,32,33)/t23-/m0/s1
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n/an/a 3.00E+3n/an/an/an/an/an/a



Neuroscience Research Centre

Curated by ChEMBL


Assay Description
Inhibition of [125 I]BH CCK-8S binding to Cholecystokinin type A receptor in pancreatic tissue


J Med Chem 39: 842-9 (1996)


Article DOI: 10.1021/jm9506736
BindingDB Entry DOI: 10.7270/Q25T3JJC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50049783
PNG
(1-((R)-1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benz...)
Show SMILES CN1c2ccccc2C(=N[C@@H](NC(=O)Nc2ccc3CCN(c4nnn[nH]4)c3c2)C1=O)c1ccccc1
Show InChI InChI=1S/C26H23N9O2/c1-34-20-10-6-5-9-19(20)22(17-7-3-2-4-8-17)28-23(24(34)36)29-26(37)27-18-12-11-16-13-14-35(21(16)15-18)25-30-32-33-31-25/h2-12,15,23H,13-14H2,1H3,(H2,27,29,37)(H,30,31,32,33)/t23-/m0/s1
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n/an/a 4.08E+3n/an/an/an/an/an/a



Neuroscience Research Centre

Curated by ChEMBL


Assay Description
Inhibition of [125 I]BH CCK-8S binding to Cholecystokinin type A receptor in pancreatic tissue


J Med Chem 39: 842-9 (1996)


Article DOI: 10.1021/jm9506736
BindingDB Entry DOI: 10.7270/Q25T3JJC
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%