Compile Data Set for Download or QSAR
maximum 50k data
Found 32 Enz. Inhib. hit(s) with all data for entry = 50006504
TargetEndothelin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050056(2-[(R)-1-[(S)-2-(3-Cyclohexyl-3-methyl-ureido)-4-m...)
Affinity DataIC50:  1.80nMAssay Description:Inhibitory activity was evaluated against human Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050063(2-[(R)-1-[(S)-2-(Cyclohexyl-methyl-carbamoyloxy)-4...)
Affinity DataIC50:  4.60nMAssay Description:Inhibitory activity was evaluated against human Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050058(2-[(R)-1-((S)-2-Cyclohexylcarbamoyloxy-4-methyl-pe...)
Affinity DataIC50:  9.30nMAssay Description:Inhibitory activity was evaluated against human Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050047(2-[(R)-1-[(S)-2-(3-Cyclohexyl-ureido)-4-methyl-pen...)
Affinity DataIC50:  11nMAssay Description:Inhibitory activity was evaluated against human Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050064(2-[(R)-1-((S)-2-Cyclohexyloxycarbonyloxy-4-methyl-...)
Affinity DataIC50:  17nMAssay Description:Inhibitory activity was evaluated against human Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050051(2-[(R)-1-((S)-2-Cyclohexylcarbamoyloxy-4-methyl-pe...)
Affinity DataIC50:  21nMAssay Description:Inhibitory activity was evaluated against human Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050055(2-[(R)-1-[(S)-2-(3-Cyclohexyl-1-methyl-ureido)-4-m...)
Affinity DataIC50:  22nMAssay Description:Inhibitory activity was evaluated against human Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050059(2-[(R)-1-[(S)-2-(3-Cyclohexyl-3-methyl-ureido)-4-m...)
Affinity DataIC50:  25nMAssay Description:Inhibitory activity was evaluated against human Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050061(2-[(R)-1-((R)-2-Cyclohexylcarbamoylmethyl-4-methyl...)
Affinity DataIC50:  29nMAssay Description:Inhibitory activity was evaluated against human Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050060(2-[(R)-1-((S)-2-Cyclohexyloxycarbonylamino-4-methy...)
Affinity DataIC50:  41nMAssay Description:Inhibitory activity was evaluated against human Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050062(2-[(R)-1-((S)-2-Cyclohexyloxycarbonylamino-4-methy...)
Affinity DataIC50:  76nMAssay Description:Inhibitory activity was evaluated against human Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050042(2-[(R)-1-[(S)-2-(3-Cyclohexyl-ureido)-4-methyl-pen...)
Affinity DataIC50:  220nMAssay Description:Inhibitory activity was evaluated against human Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050054(2-[(R)-1-((R)-2-Cyclohexylcarbamoylmethyl-4-methyl...)
Affinity DataIC50:  310nMAssay Description:Inhibitory activity was evaluated against human Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050052(2-[(R)-1-[(S)-2-(3-Cyclohexyl-1-methyl-ureido)-4-m...)
Affinity DataIC50:  450nMAssay Description:Inhibitory activity was evaluated against human Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050057(2-[(R)-1-[(S)-2-(2-Cyclohexyl-acetylamino)-4-methy...)
Affinity DataIC50:  470nMAssay Description:Inhibitory activity was evaluated against human Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050053(2-[(R)-1-[(S)-2-(2-Cyclohexyl-acetylamino)-4-methy...)
Affinity DataIC50:  680nMAssay Description:Inhibitory activity was evaluated against human Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050056(2-[(R)-1-[(S)-2-(3-Cyclohexyl-3-methyl-ureido)-4-m...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibitory activity was evaluated against human Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050047(2-[(R)-1-[(S)-2-(3-Cyclohexyl-ureido)-4-methyl-pen...)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibitory activity was evaluated against human Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050051(2-[(R)-1-((S)-2-Cyclohexylcarbamoyloxy-4-methyl-pe...)
Affinity DataIC50:  4.80E+4nMAssay Description:Inhibitory activity was evaluated against human Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050058(2-[(R)-1-((S)-2-Cyclohexylcarbamoyloxy-4-methyl-pe...)
Affinity DataIC50:  5.40E+4nMAssay Description:Inhibitory activity was evaluated against human Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050064(2-[(R)-1-((S)-2-Cyclohexyloxycarbonyloxy-4-methyl-...)
Affinity DataIC50:  7.90E+4nMAssay Description:Inhibitory activity was evaluated against human Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050063(2-[(R)-1-[(S)-2-(Cyclohexyl-methyl-carbamoyloxy)-4...)
Affinity DataIC50:  9.00E+4nMAssay Description:Inhibitory activity was evaluated against human Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050057(2-[(R)-1-[(S)-2-(2-Cyclohexyl-acetylamino)-4-methy...)
Affinity DataIC50: >9.00E+4nMAssay Description:Inhibitory activity was evaluated against human Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050052(2-[(R)-1-[(S)-2-(3-Cyclohexyl-1-methyl-ureido)-4-m...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity was evaluated against human Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050061(2-[(R)-1-((R)-2-Cyclohexylcarbamoylmethyl-4-methyl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity was evaluated against human Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050042(2-[(R)-1-[(S)-2-(3-Cyclohexyl-ureido)-4-methyl-pen...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity was evaluated against human Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050053(2-[(R)-1-[(S)-2-(2-Cyclohexyl-acetylamino)-4-methy...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity was evaluated against human Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050054(2-[(R)-1-((R)-2-Cyclohexylcarbamoylmethyl-4-methyl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity was evaluated against human Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050062(2-[(R)-1-((S)-2-Cyclohexyloxycarbonylamino-4-methy...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity was evaluated against human Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050059(2-[(R)-1-[(S)-2-(3-Cyclohexyl-3-methyl-ureido)-4-m...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity was evaluated against human Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050055(2-[(R)-1-[(S)-2-(3-Cyclohexyl-1-methyl-ureido)-4-m...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity was evaluated against human Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050060(2-[(R)-1-((S)-2-Cyclohexyloxycarbonylamino-4-methy...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity was evaluated against human Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed