BindingDB logo
myBDB logout

PubMed code 8642568

Compile data set for download or QSAR
Found 28 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50050527
PNG
(Boronic acid derivative | CHEMBL66032)
Show SMILES CC[C@H](N)C(=O)N1CCC[C@H]1B(O)O
Show InChI InChI=1S/C8H17BN2O3/c1-2-6(10)8(12)11-5-3-4-7(11)9(13)14/h6-7,13-14H,2-5,10H2,1H3/t6-,7-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 11n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro for inhibition of Dipeptidylpeptidase IV.


J Med Chem 39: 2087-94 (1996)


Article DOI: 10.1021/jm950732f
BindingDB Entry DOI: 10.7270/Q29Z95K5
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50050513
PNG
((R)-1-((S)-2-amino-3-methylbutanoyl)pyrrolidin-2-y...)
Show SMILES CC(C)[C@H](N)C(=O)N1CCC[C@H]1B(O)O
Show InChI InChI=1S/C9H19BN2O3/c1-6(2)8(11)9(13)12-5-3-4-7(12)10(14)15/h6-8,14-15H,3-5,11H2,1-2H3/t7-,8-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 15n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Compound was tested in vitro for inhibition of Dipeptidylpeptidase II


J Med Chem 39: 2087-94 (1996)


Article DOI: 10.1021/jm950732f
BindingDB Entry DOI: 10.7270/Q29Z95K5
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50050525
PNG
((R)-1-((S)-2-aminopropanoyl)pyrrolidin-2-ylboronic...)
Show SMILES C[C@H](N)C(=O)N1CCC[C@H]1B(O)O
Show InChI InChI=1S/C7H15BN2O3/c1-5(9)7(11)10-4-2-3-6(10)8(12)13/h5-6,12-13H,2-4,9H2,1H3/t5-,6-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 15n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro for inhibition of Dipeptidylpeptidase IV.


J Med Chem 39: 2087-94 (1996)


Article DOI: 10.1021/jm950732f
BindingDB Entry DOI: 10.7270/Q29Z95K5
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50050521
PNG
((2-Dihydroxyborane-pyrrolidin-1-yl)-pyrrolidin-2-y...)
Show SMILES OB(O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1
Show InChI InChI=1S/C9H17BN2O3/c13-9(7-3-1-5-11-7)12-6-2-4-8(12)10(14)15/h7-8,11,14-15H,1-6H2/t7-,8-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
PC cid
PC sid
PDB
UniChem

Patents


Similars

PDB
Article
PubMed
n/an/a 20n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro for inhibition of Dipeptidylpeptidase IV.


J Med Chem 39: 2087-94 (1996)


Article DOI: 10.1021/jm950732f
BindingDB Entry DOI: 10.7270/Q29Z95K5
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50050517
PNG
(Boronic acid derivative | CHEMBL305170 | N-alkyl G...)
Show SMILES CC(C)[C@@H](N)C(=O)N1CCC[C@H]1B(O)O
Show InChI InChI=1S/C9H19BN2O3/c1-6(2)8(11)9(13)12-5-3-4-7(12)10(14)15/h6-8,14-15H,3-5,11H2,1-2H3/t7-,8+/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 21n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Compound was tested in vitro for inhibition of Dipeptidylpeptidase II


J Med Chem 39: 2087-94 (1996)


Article DOI: 10.1021/jm950732f
BindingDB Entry DOI: 10.7270/Q29Z95K5
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50369128
PNG
(CHEMBL1790483)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1CCC[C@H]1B(O)O
Show InChI InChI=1S/C10H21BN2O3/c1-3-7(2)9(12)10(14)13-6-4-5-8(13)11(15)16/h7-9,15-16H,3-6,12H2,1-2H3/t7-,8-,9-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 25n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro for inhibition of Dipeptidylpeptidase IV.


J Med Chem 39: 2087-94 (1996)


Article DOI: 10.1021/jm950732f
BindingDB Entry DOI: 10.7270/Q29Z95K5
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50050513
PNG
((R)-1-((S)-2-amino-3-methylbutanoyl)pyrrolidin-2-y...)
Show SMILES CC(C)[C@H](N)C(=O)N1CCC[C@H]1B(O)O
Show InChI InChI=1S/C9H19BN2O3/c1-6(2)8(11)9(13)12-5-3-4-7(12)10(14)15/h6-8,14-15H,3-5,11H2,1-2H3/t7-,8-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 26n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro for inhibition of Dipeptidylpeptidase IV.


J Med Chem 39: 2087-94 (1996)


Article DOI: 10.1021/jm950732f
BindingDB Entry DOI: 10.7270/Q29Z95K5
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50050514
PNG
(Boronic acid derivative | CHEMBL304007)
Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1B(O)O
Show InChI InChI=1S/C13H19BN2O4/c15-11(8-9-3-5-10(17)6-4-9)13(18)16-7-1-2-12(16)14(19)20/h3-6,11-12,17,19-20H,1-2,7-8,15H2/t11-,12-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 32n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro for inhibition of Dipeptidylpeptidase IV.


J Med Chem 39: 2087-94 (1996)


Article DOI: 10.1021/jm950732f
BindingDB Entry DOI: 10.7270/Q29Z95K5
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50050528
PNG
(Boronic acid derivative | CHEMBL63698)
Show SMILES CC(C)C[C@H](N)C(=O)N1CCC[C@H]1B(O)O
Show InChI InChI=1S/C10H21BN2O3/c1-7(2)6-8(12)10(14)13-5-3-4-9(13)11(15)16/h7-9,15-16H,3-6,12H2,1-2H3/t8-,9-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 44n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro for inhibition of Dipeptidylpeptidase IV.


J Med Chem 39: 2087-94 (1996)


Article DOI: 10.1021/jm950732f
BindingDB Entry DOI: 10.7270/Q29Z95K5
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50050525
PNG
((R)-1-((S)-2-aminopropanoyl)pyrrolidin-2-ylboronic...)
Show SMILES C[C@H](N)C(=O)N1CCC[C@H]1B(O)O
Show InChI InChI=1S/C7H15BN2O3/c1-5(9)7(11)10-4-2-3-6(10)8(12)13/h5-6,12-13H,2-4,9H2,1H3/t5-,6-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 60n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Compound was tested in vitro for inhibition of Dipeptidylpeptidase II


J Med Chem 39: 2087-94 (1996)


Article DOI: 10.1021/jm950732f
BindingDB Entry DOI: 10.7270/Q29Z95K5
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50050520
PNG
(Boronic acid derivative | CHEMBL63406)
Show SMILES CC(C)(C)[C@H](N)C(=O)N1CCC[C@H]1B(O)O
Show InChI InChI=1S/C10H21BN2O3/c1-10(2,3)8(12)9(14)13-6-4-5-7(13)11(15)16/h7-8,15-16H,4-6,12H2,1-3H3/t7-,8+/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 60n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro for inhibition of Dipeptidylpeptidase IV.


J Med Chem 39: 2087-94 (1996)


Article DOI: 10.1021/jm950732f
BindingDB Entry DOI: 10.7270/Q29Z95K5
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50050524
PNG
(Boronic acid derivative | CHEMBL291428)
Show SMILES N[C@H](C(=O)N1CCC[C@H]1B(O)O)c1ccccc1
Show InChI InChI=1S/C12H17BN2O3/c14-11(9-5-2-1-3-6-9)12(16)15-8-4-7-10(15)13(17)18/h1-3,5-6,10-11,17-18H,4,7-8,14H2/t10-,11-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 63n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro for inhibition of Dipeptidylpeptidase IV.


J Med Chem 39: 2087-94 (1996)


Article DOI: 10.1021/jm950732f
BindingDB Entry DOI: 10.7270/Q29Z95K5
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50050515
PNG
(Boronic acid derivative | CHEMBL63652)
Show SMILES N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1B(O)O
Show InChI InChI=1S/C13H19BN2O3/c15-11(9-10-5-2-1-3-6-10)13(17)16-8-4-7-12(16)14(18)19/h1-3,5-6,11-12,18-19H,4,7-9,15H2/t11-,12-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 70n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro for inhibition of Dipeptidylpeptidase IV.


J Med Chem 39: 2087-94 (1996)


Article DOI: 10.1021/jm950732f
BindingDB Entry DOI: 10.7270/Q29Z95K5
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50050516
PNG
(Boronic acid derivative | CHEMBL63726)
Show SMILES NCCCC[C@H](N)C(=O)N1CCC[C@H]1B(O)O
Show InChI InChI=1S/C10H22BN3O3/c12-6-2-1-4-8(13)10(15)14-7-3-5-9(14)11(16)17/h8-9,16-17H,1-7,12-13H2/t8-,9-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 95n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro for inhibition of Dipeptidylpeptidase IV.


J Med Chem 39: 2087-94 (1996)


Article DOI: 10.1021/jm950732f
BindingDB Entry DOI: 10.7270/Q29Z95K5
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50369129
PNG
(CHEMBL1790478)
Show SMILES C[C@@H](O)[C@H](N)C(=O)N1CCC[C@H]1B(O)O
Show InChI InChI=1S/C8H17BN2O4/c1-5(12)7(10)8(13)11-4-2-3-6(11)9(14)15/h5-7,12,14-15H,2-4,10H2,1H3/t5-,6+,7+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 190n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro for inhibition of Dipeptidylpeptidase IV.


J Med Chem 39: 2087-94 (1996)


Article DOI: 10.1021/jm950732f
BindingDB Entry DOI: 10.7270/Q29Z95K5
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50050526
PNG
(Boronic acid derivative | CHEMBL292342)
Show SMILES OB(O)[C@@H]1CCCN1C(=O)[C@@H]1CCN1
Show InChI InChI=1S/C8H15BN2O3/c12-8(6-3-4-10-6)11-5-1-2-7(11)9(13)14/h6-7,10,13-14H,1-5H2/t6-,7-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 250n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro for inhibition of Dipeptidylpeptidase IV.


J Med Chem 39: 2087-94 (1996)


Article DOI: 10.1021/jm950732f
BindingDB Entry DOI: 10.7270/Q29Z95K5
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50369129
PNG
(CHEMBL1790478)
Show SMILES C[C@@H](O)[C@H](N)C(=O)N1CCC[C@H]1B(O)O
Show InChI InChI=1S/C8H17BN2O4/c1-5(12)7(10)8(13)11-4-2-3-6(11)9(14)15/h5-7,12,14-15H,2-4,10H2,1H3/t5-,6+,7+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 730n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Compound was tested in vitro for inhibition of Dipeptidylpeptidase II


J Med Chem 39: 2087-94 (1996)


Article DOI: 10.1021/jm950732f
BindingDB Entry DOI: 10.7270/Q29Z95K5
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50050521
PNG
((2-Dihydroxyborane-pyrrolidin-1-yl)-pyrrolidin-2-y...)
Show SMILES OB(O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1
Show InChI InChI=1S/C9H17BN2O3/c13-9(7-3-1-5-11-7)12-6-2-4-8(12)10(14)15/h7-8,11,14-15H,1-6H2/t7-,8-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
PC cid
PC sid
PDB
UniChem

Patents


Similars

Article
PubMed
n/an/a 770n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Compound was tested in vitro for inhibition of Dipeptidylpeptidase II


J Med Chem 39: 2087-94 (1996)


Article DOI: 10.1021/jm950732f
BindingDB Entry DOI: 10.7270/Q29Z95K5
More data for this
Ligand-Target Pair
Prolyl endopeptidase


(Homo sapiens (Human))
BDBM50050525
PNG
((R)-1-((S)-2-aminopropanoyl)pyrrolidin-2-ylboronic...)
Show SMILES C[C@H](N)C(=O)N1CCC[C@H]1B(O)O
Show InChI InChI=1S/C7H15BN2O3/c1-5(9)7(11)10-4-2-3-6(10)8(12)13/h5-6,12-13H,2-4,9H2,1H3/t5-,6-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Compound was tested in vitro for inhibition of Prolyl endopeptidase


J Med Chem 39: 2087-94 (1996)


Article DOI: 10.1021/jm950732f
BindingDB Entry DOI: 10.7270/Q29Z95K5
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50050512
PNG
(Boronic acid derivative | CHEMBL65406)
Show SMILES CC(C)[C@@H](N)C(=O)N1CCC[C@@H]1B(O)O
Show InChI InChI=1S/C9H19BN2O3/c1-6(2)8(11)9(13)12-5-3-4-7(12)10(14)15/h6-8,14-15H,3-5,11H2,1-2H3/t7-,8-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.00E+3n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro for inhibition of Dipeptidylpeptidase IV.


J Med Chem 39: 2087-94 (1996)


Article DOI: 10.1021/jm950732f
BindingDB Entry DOI: 10.7270/Q29Z95K5
More data for this
Ligand-Target Pair
Prolyl endopeptidase


(Homo sapiens (Human))
BDBM50369129
PNG
(CHEMBL1790478)
Show SMILES C[C@@H](O)[C@H](N)C(=O)N1CCC[C@H]1B(O)O
Show InChI InChI=1S/C8H17BN2O4/c1-5(12)7(10)8(13)11-4-2-3-6(11)9(14)15/h5-7,12,14-15H,2-4,10H2,1H3/t5-,6+,7+/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.00E+3n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Compound was tested in vitro for inhibition of Prolyl endopeptidase


J Med Chem 39: 2087-94 (1996)


Article DOI: 10.1021/jm950732f
BindingDB Entry DOI: 10.7270/Q29Z95K5
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50050511
PNG
((R)-1-(2-aminoacetyl)pyrrolidin-2-ylboronic acid |...)
Show SMILES NCC(=O)N1CCC[C@H]1B(O)O
Show InChI InChI=1S/C6H13BN2O3/c8-4-6(10)9-3-1-2-5(9)7(11)12/h5,11-12H,1-4,8H2/t5-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.60E+4n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro for inhibition of Dipeptidylpeptidase IV.


J Med Chem 39: 2087-94 (1996)


Article DOI: 10.1021/jm950732f
BindingDB Entry DOI: 10.7270/Q29Z95K5
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50050519
PNG
(Boronic acid derivative | CHEMBL303131)
Show SMILES N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1B(O)O
Show InChI InChI=1S/C10H17BN4O3/c12-8(4-7-5-13-6-14-7)10(16)15-3-1-2-9(15)11(17)18/h5-6,8-9,17-18H,1-4,12H2,(H,13,14)/t8-,9-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.70E+4n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro for inhibition of Dipeptidylpeptidase IV.


J Med Chem 39: 2087-94 (1996)


Article DOI: 10.1021/jm950732f
BindingDB Entry DOI: 10.7270/Q29Z95K5
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50050512
PNG
(Boronic acid derivative | CHEMBL65406)
Show SMILES CC(C)[C@@H](N)C(=O)N1CCC[C@@H]1B(O)O
Show InChI InChI=1S/C9H19BN2O3/c1-6(2)8(11)9(13)12-5-3-4-7(12)10(14)15/h6-8,14-15H,3-5,11H2,1-2H3/t7-,8-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.80E+4n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Compound was tested in vitro for inhibition of Dipeptidylpeptidase II


J Med Chem 39: 2087-94 (1996)


Article DOI: 10.1021/jm950732f
BindingDB Entry DOI: 10.7270/Q29Z95K5
More data for this
Ligand-Target Pair
Prolyl endopeptidase


(Homo sapiens (Human))
BDBM50050513
PNG
((R)-1-((S)-2-amino-3-methylbutanoyl)pyrrolidin-2-y...)
Show SMILES CC(C)[C@H](N)C(=O)N1CCC[C@H]1B(O)O
Show InChI InChI=1S/C9H19BN2O3/c1-6(2)8(11)9(13)12-5-3-4-7(12)10(14)15/h6-8,14-15H,3-5,11H2,1-2H3/t7-,8-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 2.30E+4n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Compound was tested in vitro for inhibition of Prolyl endopeptidase


J Med Chem 39: 2087-94 (1996)


Article DOI: 10.1021/jm950732f
BindingDB Entry DOI: 10.7270/Q29Z95K5
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50050523
PNG
(Boronic acid derivative | CHEMBL66189)
Show SMILES CC(C)(N)C(=O)N1CCC[C@H]1B(O)O
Show InChI InChI=1S/C8H17BN2O3/c1-8(2,10)7(12)11-5-3-4-6(11)9(13)14/h6,13-14H,3-5,10H2,1-2H3/t6-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.00E+4n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro for inhibition of Dipeptidylpeptidase IV.


J Med Chem 39: 2087-94 (1996)


Article DOI: 10.1021/jm950732f
BindingDB Entry DOI: 10.7270/Q29Z95K5
More data for this
Ligand-Target Pair
Prolyl endopeptidase


(Homo sapiens (Human))
BDBM50050517
PNG
(Boronic acid derivative | CHEMBL305170 | N-alkyl G...)
Show SMILES CC(C)[C@@H](N)C(=O)N1CCC[C@H]1B(O)O
Show InChI InChI=1S/C9H19BN2O3/c1-6(2)8(11)9(13)12-5-3-4-7(12)10(14)15/h6-8,14-15H,3-5,11H2,1-2H3/t7-,8+/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.10E+4n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Compound was tested in vitro for inhibition of Prolyl endopeptidase


J Med Chem 39: 2087-94 (1996)


Article DOI: 10.1021/jm950732f
BindingDB Entry DOI: 10.7270/Q29Z95K5
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50050517
PNG
(Boronic acid derivative | CHEMBL305170 | N-alkyl G...)
Show SMILES CC(C)[C@@H](N)C(=O)N1CCC[C@H]1B(O)O
Show InChI InChI=1S/C9H19BN2O3/c1-6(2)8(11)9(13)12-5-3-4-7(12)10(14)15/h6-8,14-15H,3-5,11H2,1-2H3/t7-,8+/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.16E+5n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
In vitro for inhibition of Dipeptidylpeptidase IV.


J Med Chem 39: 2087-94 (1996)


Article DOI: 10.1021/jm950732f
BindingDB Entry DOI: 10.7270/Q29Z95K5
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%