Compile Data Set for Download or QSAR
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Found 28 Enz. Inhib. hit(s) with all data for entry = 1203
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

LigandPNGBDBM9955((8S)-2,8,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{1...)
Affinity DataKi:  3.10nM ΔG°:  -50.5kJ/mole IC50:  37nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

LigandPNGBDBM9960((8R)-2,8,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{1...)
Affinity DataKi:  5.30nM ΔG°:  -49.1kJ/mole IC50:  49nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

LigandPNGBDBM9968((8R)-8-hydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,...)
Affinity DataKi:  6nM ΔG°:  -48.8kJ/mole IC50:  50nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

LigandPNGBDBM9981(2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]he...)
Affinity DataKi:  6.80nM IC50:  60nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

LigandPNGBDBM9967((8S)-8-methoxy-2,15-dimethyltetracyclo[8.7.0.0^{2,...)
Affinity DataKi:  12nM ΔG°:  -47.0kJ/mole IC50:  120nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

LigandPNGBDBM9970((8R)-8-methoxy-2,15-dimethyltetracyclo[8.7.0.0^{2,...)
Affinity DataKi:  12nM IC50:  130nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

LigandPNGBDBM9956((8S)-8-ethyl-2,15-dimethyltetracyclo[8.7.0.0^{2,7}...)
Affinity DataKi:  14nM ΔG°:  -46.6kJ/mole IC50:  110nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

LigandPNGBDBM9966((8S)-2,15-dimethyl-14-oxotetracyclo[8.7.0.0^{2,7}....)
Affinity DataKi:  18nM ΔG°:  -46.0kJ/mole IC50:  160nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

LigandPNGBDBM9965((8S)-8-hydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,...)
Affinity DataKi:  21nM ΔG°:  -45.6kJ/mole IC50:  190nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

LigandPNGBDBM9969((8R)-2,15-dimethyl-14-oxotetracyclo[8.7.0.0^{2,7}....)
Affinity DataKi:  24nM IC50:  260nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

LigandPNGBDBM9957((8S)-2,15-dimethyl-8-propyltetracyclo[8.7.0.0^{2,7...)
Affinity DataKi:  30nM ΔG°:  -44.7kJ/mole IC50:  230nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

LigandPNGBDBM9961((8R)-8-ethyl-2,15-dimethyltetracyclo[8.7.0.0^{2,7}...)
Affinity DataKi:  43nM ΔG°:  -43.7kJ/mole IC50:  320nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

LigandPNGBDBM9982((14S)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,...)
Affinity DataKi:  45nM IC50:  360nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

LigandPNGBDBM9962((8R)-2,15-dimethyl-8-propyltetracyclo[8.7.0.0^{2,7...)
Affinity DataKi:  51nM ΔG°:  -43.3kJ/mole IC50:  440nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

LigandPNGBDBM9976((8R)-2,8,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{1...)
Affinity DataKi:  140nM IC50:  1.60E+3nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

LigandPNGBDBM9972((8S)-8-ethyl-2,15-dimethyltetracyclo[8.7.0.0^{2,7}...)
Affinity DataKi:  180nM IC50:  1.30E+3nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

LigandPNGBDBM9977((8R)-8-ethyl-2,15-dimethyltetracyclo[8.7.0.0^{2,7}...)
Affinity DataKi:  340nM IC50:  3.30E+3nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

LigandPNGBDBM9971((8S)-2,8,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{1...)
Affinity DataKi:  380nM IC50:  3.70E+3nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

LigandPNGBDBM9958((8S)-2,15-dimethyl-8-pentyltetracyclo[8.7.0.0^{2,7...)
Affinity DataKi:  400nM ΔG°:  -38.0kJ/mole IC50:  9.00E+3nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

LigandPNGBDBM9963((8R)-2,15-dimethyl-8-pentyltetracyclo[8.7.0.0^{2,7...)
Affinity DataKi:  1.20E+3nM ΔG°:  -35.2kJ/mole IC50:  1.20E+4nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

LigandPNGBDBM9964((8R)-2,15-dimethyl-8-octyltetracyclo[8.7.0.0^{2,7}...)
Affinity DataKi:  2.60E+3nM ΔG°:  -33.2kJ/mole IC50: >5.00E+4nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

LigandPNGBDBM9973((8S)-2,15-dimethyl-8-propyltetracyclo[8.7.0.0^{2,7...)
Affinity DataKi:  2.90E+3nM IC50:  1.40E+4nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

LigandPNGBDBM9959((8S)-2,15-dimethyl-8-octyltetracyclo[8.7.0.0^{2,7}...)
Affinity DataKi:  4.10E+3nM ΔG°:  -32.0kJ/mole IC50: >5.00E+4nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

LigandPNGBDBM9978((8R)-2,15-dimethyl-8-propyltetracyclo[8.7.0.0^{2,7...)
Affinity DataKi:  5.50E+3nM IC50:  4.30E+4nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

LigandPNGBDBM9974((8S)-2,15-dimethyl-8-pentyltetracyclo[8.7.0.0^{2,7...)
Affinity DataKi:  4.40E+4nM IC50: >5.00E+4nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

LigandPNGBDBM9979((8R)-2,15-dimethyl-8-pentyltetracyclo[8.7.0.0^{2,7...)
Affinity DataKi:  1.00E+5nM IC50: >5.00E+4nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

LigandPNGBDBM9980((8R)-2,15-dimethyl-8-octyltetracyclo[8.7.0.0^{2,7}...)
Affinity DataIC50: >5.00E+4nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

LigandPNGBDBM9975((8S)-2,15-dimethyl-8-octyltetracyclo[8.7.0.0^{2,7}...)
Affinity DataIC50: >5.00E+4nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed