Compile Data Set for Download or QSAR
maximum 50k data
Found 24 Enz. Inhib. hit(s) with all data for entry = 50006950
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Sus scrofa (Pig))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50037078(2-(Phenyl)-isothiazolo[5,4-b]pyridin-3(2H)-one | 2...)
Affinity DataIC50:  190nMAssay Description:Inhibition of porcine gastric H+/K+ ATPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Sus scrofa (Pig))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056046(2-Pyridin-4-yl-isothiazolo[5,4-b]pyridin-3-one | C...)
Affinity DataIC50:  220nMAssay Description:Inhibition of porcine gastric H+/K+ ATPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50241343((RS)-6-methoxy-2-((4-methoxy-3,5-dimethylpyridin-2...)
Affinity DataIC50:  370nMAssay Description:Inhibition of [14C]-aminopyrine (AP) accumulation stimulated by dibutyryl cyclic AMP in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056043(2-(2,4-Diethoxy-phenylmethanesulfinyl)-N-pyridin-4...)
Affinity DataIC50:  400nMAssay Description:Inhibition of [14C]-aminopyrine (AP) accumulation stimulated by dibutyryl cyclic AMP in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056045(2-(2-Ethoxy-4-methoxy-phenylmethanesulfinyl)-N-pyr...)
Affinity DataIC50:  450nMAssay Description:Inhibition of [14C]-aminopyrine (AP) accumulation stimulated by dibutyryl cyclic AMP in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056041(2-(2,4-Dimethoxy-6-methyl-phenylmethanesulfinyl)-N...)
Affinity DataIC50:  460nMAssay Description:Inhibition of [14C]-aminopyrine (AP) accumulation stimulated by dibutyryl cyclic AMP in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Sus scrofa (Pig))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056049(2-Isobutyl-isothiazolo[5,4-b]pyridin-3-one | CHEMB...)
Affinity DataIC50:  530nMAssay Description:Inhibition of porcine gastric H+/K+ ATPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056056(2-(2,4-Dimethoxy-phenylmethanesulfinyl)-N-pyridin-...)
Affinity DataIC50:  590nMAssay Description:Inhibition of [14C]-aminopyrine (AP) accumulation stimulated by dibutyryl cyclic AMP in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056042(CHEMBL108285 | N-Pyridin-4-yl-2-(2,4,6-trimethoxy-...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of [14C]-aminopyrine (AP) accumulation stimulated by dibutyryl cyclic AMP in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056050(2-(Di-p-tolyl-methanesulfinyl)-N-pyridin-4-yl-nico...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of [14C]-aminopyrine (AP) accumulation stimulated by dibutyryl cyclic AMP in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056051(2-[2-(2-Fluoro-ethoxy)-4-methoxy-phenylmethanesulf...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of [14C]-aminopyrine (AP) accumulation stimulated by dibutyryl cyclic AMP in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056047(2-(5-Bromo-2,4-dimethoxy-phenylmethanesulfinyl)-N-...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of [14C]-aminopyrine (AP) accumulation stimulated by dibutyryl cyclic AMP in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Sus scrofa (Pig))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056042(CHEMBL108285 | N-Pyridin-4-yl-2-(2,4,6-trimethoxy-...)
Affinity DataIC50:  7.30E+3nMAssay Description:Inhibition of porcine gastric H+/K+ ATPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056044(2-(2,4-Dimethoxy-3-methyl-phenylmethanesulfinyl)-N...)
Affinity DataIC50:  1.66E+4nMAssay Description:Inhibition of [14C]-aminopyrine (AP) accumulation stimulated by dibutyryl cyclic AMP in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056052(2-(2,6-Dimethoxy-phenylmethanesulfinyl)-N-pyridin-...)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of [14C]-aminopyrine (AP) accumulation stimulated by dibutyryl cyclic AMP in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056054(2-[2-(2-Hydroxy-ethoxy)-4-methoxy-phenylmethanesul...)
Affinity DataIC50:  5.90E+4nMAssay Description:Inhibition of [14C]-aminopyrine (AP) accumulation stimulated by dibutyryl cyclic AMP in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Sus scrofa (Pig))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056052(2-(2,6-Dimethoxy-phenylmethanesulfinyl)-N-pyridin-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of porcine gastric H+/K+ ATPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Sus scrofa (Pig))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056041(2-(2,4-Dimethoxy-6-methyl-phenylmethanesulfinyl)-N...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of porcine gastric H+/K+ ATPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Sus scrofa (Pig))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056044(2-(2,4-Dimethoxy-3-methyl-phenylmethanesulfinyl)-N...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of porcine gastric H+/K+ ATPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Sus scrofa (Pig))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056056(2-(2,4-Dimethoxy-phenylmethanesulfinyl)-N-pyridin-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of porcine gastric H+/K+ ATPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Sus scrofa (Pig))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056045(2-(2-Ethoxy-4-methoxy-phenylmethanesulfinyl)-N-pyr...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of porcine gastric H+/K+ ATPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Sus scrofa (Pig))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056051(2-[2-(2-Fluoro-ethoxy)-4-methoxy-phenylmethanesulf...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of porcine gastric H+/K+ ATPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Sus scrofa (Pig))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056043(2-(2,4-Diethoxy-phenylmethanesulfinyl)-N-pyridin-4...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of porcine gastric H+/K+ ATPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Sus scrofa (Pig))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056048(CHEMBL432440 | N-Pyridin-4-yl-2-(2,4,5-trimethoxy-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of porcine gastric H+/K+ ATPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed