Compile Data Set for Download or QSAR
maximum 50k data
Found 37 Enz. Inhib. hit(s) with all data for entry = 50006995
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50056605(7-Chloro-6-methyl-5-nitro-1,4-dihydro-quinoxaline-...)
Affinity DataIC50:  4.70nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50038161(6,7-Dichloro-3-hydroxy-5-nitro-3,4-dihydro-1H-quin...)
Affinity DataIC50:  5.90nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50056596(7-Bromo-6-methyl-5-nitro-1,4-dihydro-quinoxaline-2...)
Affinity DataIC50:  8.70nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50056618(6,7-Dibromo-5-nitro-1,4-dihydro-quinoxaline-2,3-di...)
Affinity DataIC50:  20nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50056620(6-Chloro-7-ethyl-5-nitro-1,4-dihydro-quinoxaline-2...)
Affinity DataIC50:  29nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50056595(6,7-Dimethyl-5-nitro-1,4-dihydro-quinoxaline-2,3-d...)
Affinity DataIC50:  29nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50056600(6-Chloro-7-methyl-5-nitro-1,4-dihydro-quinoxaline-...)
Affinity DataIC50:  45nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50056591(7-Bromo-6-methoxy-5-nitro-1,4-dihydro-quinoxaline-...)
Affinity DataIC50:  64nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50056598(7-Methyl-8-nitro-2,3-dioxo-1,2,3,4-tetrahydro-quin...)
Affinity DataIC50:  73nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50056611(6-Bromo-7-ethyl-5-nitro-1,4-dihydro-quinoxaline-2,...)
Affinity DataIC50:  82nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50056597(7-Fluoro-6-methyl-5-nitro-1,4-dihydro-quinoxaline-...)
Affinity DataIC50:  95nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50056592(7-Chloro-6-ethyl-5-nitro-1,4-dihydro-quinoxaline-2...)
Affinity DataIC50:  130nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Cocensys

Curated by ChEMBL
LigandPNGBDBM22778(6,7-Dichloro-1,4-dihydro-quinoxaline-2,3-dione | 6...)
Affinity DataIC50:  130nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50056615(5-Amino-7-chloro-6-methyl-1,4-dihydro-quinoxaline-...)
Affinity DataIC50:  150nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50056621(7-Chloro-6-methoxy-5-nitro-1,4-dihydro-quinoxaline...)
Affinity DataIC50:  150nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50056606(6,7-Diethyl-5-nitro-1,4-dihydro-quinoxaline-2,3-di...)
Affinity DataIC50:  160nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50056593(7-Chloro-6-ethylsulfanyl-5-nitro-1,4-dihydro-quino...)
Affinity DataIC50:  640nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50056622(6-Chloro-7-methyl-1,4-dihydro-quinoxaline-2,3-dion...)
Affinity DataIC50:  780nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50056614(6-Bromo-7-methoxy-1,4-dihydro-quinoxaline-2,3-dion...)
Affinity DataIC50:  1.00E+3nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50056613(6-Chloro-7-ethyl-1,4-dihydro-quinoxaline-2,3-dione...)
Affinity DataIC50:  1.40E+3nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50056623(6,7-Diethyl-1,4-dihydro-quinoxaline-2,3-dione | CH...)
Affinity DataIC50:  1.80E+3nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50056610(7-Fluoro-6-methoxy-5-nitro-1,4-dihydro-quinoxaline...)
Affinity DataIC50:  1.90E+3nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50056594(8-Nitro-2,3-dioxo-1,2,3,4-tetrahydro-quinoxaline-6...)
Affinity DataIC50:  2.80E+3nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50056602(5-Nitro-4,6,7,8-tetrahydro-1H-cyclopenta[g]quinoxa...)
Affinity DataIC50:  3.10E+3nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50008768(6,7-Dimethyl-1,4-dihydro-quinoxaline-2,3-dione | C...)
Affinity DataIC50:  3.30E+3nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50056616(6-Ethoxy-7-fluoro-5-nitro-1,4-dihydro-quinoxaline-...)
Affinity DataIC50:  3.60E+3nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50056617(7-Fluoro-5-nitro-6-(3-phenyl-propoxy)-1,4-dihydro-...)
Affinity DataIC50:  4.00E+3nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50056624(6-Butoxy-7-fluoro-5-nitro-1,4-dihydro-quinoxaline-...)
Affinity DataIC50:  4.30E+3nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50056601(7-Methyl-5-nitro-1,4-dihydro-quinoxaline-2,3-dione...)
Affinity DataIC50:  9.30E+3nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50056612(6-Amino-7-fluoro-5-nitro-1,4-dihydro-quinoxaline-2...)
Affinity DataIC50:  1.10E+4nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50056619(4,6,7,8-Tetrahydro-1H-cyclopenta[g]quinoxaline-2,3...)
Affinity DataIC50:  1.50E+4nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50056607(1,4-Dihydro-benzo[g]quinoxaline-2,3-dione | CHEMBL...)
Affinity DataIC50:  1.60E+4nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50056599(6,7-Dimethoxy-1,4-dihydro-quinoxaline-2,3-dione | ...)
Affinity DataIC50:  1.70E+4nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50056604(5-Hydroxy-6,7-dimethoxy-1,4-dihydro-quinoxaline-2,...)
Affinity DataIC50:  1.70E+4nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50056603(Acetic acid 6,7-dimethoxy-2,3-dioxo-1,2,3,4-tetrah...)
Affinity DataIC50:  5.30E+4nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50056609(5,8-Dihydro-1,3-dioxa-5,8-diaza-cyclopenta[b]napht...)
Affinity DataIC50: >1.00E+5nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50056608(6,7-Dihydroxy-1,4-dihydro-quinoxaline-2,3-dione | ...)
Affinity DataIC50: >1.00E+5nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed