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Found 11 Enz. Inhib. hit(s) with all data for entry = 50007408
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Oxis International

Curated by ChEMBL
LigandPNGBDBM50029781((R)-(+)-N-{3-[5-(4-fluorobenzyl)thien-2-yl]-1-meth...)
Affinity DataIC50:  23nMAssay Description:Inhibitory activity against 5-lipoxygenase obtained from rat basophilic leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Oxis International

Curated by ChEMBL
LigandPNGBDBM50062675(5-{4-[5-(4-Fluoro-benzyl)-thiophen-2-yl]-but-3-yny...)
Affinity DataIC50:  160nMAssay Description:Inhibitory activity against 5-lipoxygenase obtained from rat basophilic leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Oxis International

Curated by ChEMBL
LigandPNGBDBM50062678(3,4-Dihydroxy-5-(4-naphthalen-1-yl-but-3-ynyl)-5H-...)
Affinity DataIC50:  300nMAssay Description:Inhibitory activity against 5-lipoxygenase obtained from rat basophilic leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Oxis International

Curated by ChEMBL
LigandPNGBDBM50062676(3,4-Dihydroxy-5-[4-(2-phenylsulfanylmethyl-phenyl)...)
Affinity DataIC50:  300nMAssay Description:Inhibitory activity against 5-lipoxygenase obtained from rat basophilic leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Oxis International

Curated by ChEMBL
LigandPNGBDBM50062677(5-{4-[((Z)-2-Hex-2-enyl)-phenyl]-but-3-ynyl}-3,4-d...)
Affinity DataIC50:  400nMAssay Description:Inhibitory activity against 5-lipoxygenase obtained from rat basophilic leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Oxis International

Curated by ChEMBL
LigandPNGBDBM50000541((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...)
Affinity DataIC50:  500nMAssay Description:Inhibitory activity against 5-lipoxygenase obtained from rat basophilic leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Oxis International

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibitory activity against Prostaglandin G/H synthase 1 isolated from ram (sheep) seminal vesicleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Oxis International

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibitory activity against Prostaglandin G/H synthase 2 obtained from sheep placentaMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Oxis International

Curated by ChEMBL
LigandPNGBDBM50000540(1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazo...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibitory activity against 5-lipoxygenase obtained from rat basophilic leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Oxis International

Curated by ChEMBL
LigandPNGBDBM22360(2-(acetyloxy)benzoate | 2-(acetyloxy)benzoic acid ...)
Affinity DataIC50:  2.40E+5nMAssay Description:Inhibitory activity against Prostaglandin G/H synthase 1 isolated from ram (sheep) seminal vesicleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Oxis International

Curated by ChEMBL
LigandPNGBDBM22360(2-(acetyloxy)benzoate | 2-(acetyloxy)benzoic acid ...)
Affinity DataIC50:  6.60E+5nMAssay Description:Inhibitory activity against Prostaglandin G/H synthase 2 obtained from sheep placentaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed