Compile Data Set for Download or QSAR
maximum 50k data
Found 16 Enz. Inhib. hit(s) with all data for entry = 50022867
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Heinrich-Heine-UniversitäT DüSseldorf

Curated by ChEMBL
LigandPNGBDBM50259940(2-[(2E)-3,7-dimethyl-2,6-octadienyl]-6-methyl-2,5-...)
Affinity DataIC50:  200nMAssay Description:Inhibition of 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Heinrich-Heine-UniversitäT DüSseldorf

Curated by ChEMBL
LigandPNGBDBM32020(4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyro...)
Affinity DataIC50:  500nMAssay Description:Inhibition of 5-lipoxygenaseMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Heinrich-Heine-UniversitäT DüSseldorf

Curated by ChEMBL
LigandPNGBDBM50259939(2,8-dimethyl-6-hydroxy-2-(4-methyl-3-pentenyl)-2h-...)
Affinity DataIC50:  600nMAssay Description:Inhibition of 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Heinrich-Heine-UniversitäT DüSseldorf

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Heinrich-Heine-UniversitäT DüSseldorf

Curated by ChEMBL
LigandPNGBDBM50259939(2,8-dimethyl-6-hydroxy-2-(4-methyl-3-pentenyl)-2h-...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Heinrich-Heine-UniversitäT DüSseldorf

Curated by ChEMBL
LigandPNGBDBM50241938(Atractylon | CHEMBL486189)
Affinity DataIC50:  2.51E+4nMAssay Description:Inhibition of 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Heinrich-Heine-UniversitäT DüSseldorf

Curated by ChEMBL
LigandPNGBDBM50240512(7-Methoxy-8-(3-methyl-but-2-enyl)-chromen-2-one | ...)
Affinity DataIC50:  3.62E+4nMAssay Description:Inhibition of 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Heinrich-Heine-UniversitäT DüSseldorf

Curated by ChEMBL
LigandPNGBDBM50259940(2-[(2E)-3,7-dimethyl-2,6-octadienyl]-6-methyl-2,5-...)
Affinity DataIC50:  6.43E+4nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Heinrich-Heine-UniversitäT DüSseldorf

Curated by ChEMBL
LigandPNGBDBM50241946(Atractylenolide II | CHEMBL485805)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Heinrich-Heine-UniversitäT DüSseldorf

Curated by ChEMBL
LigandPNGBDBM50241938(Atractylon | CHEMBL486189)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Heinrich-Heine-UniversitäT DüSseldorf

Curated by ChEMBL
LigandPNGBDBM50241939(Atractylenolide I | CHEMBL449520)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Heinrich-Heine-UniversitäT DüSseldorf

Curated by ChEMBL
LigandPNGBDBM50241946(Atractylenolide II | CHEMBL485805)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Heinrich-Heine-UniversitäT DüSseldorf

Curated by ChEMBL
LigandPNGBDBM50241945(Atractylenolide III | CHEMBL486961)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Heinrich-Heine-UniversitäT DüSseldorf

Curated by ChEMBL
LigandPNGBDBM50241945(Atractylenolide III | CHEMBL486961)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Heinrich-Heine-UniversitäT DüSseldorf

Curated by ChEMBL
LigandPNGBDBM50240512(7-Methoxy-8-(3-methyl-but-2-enyl)-chromen-2-one | ...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Heinrich-Heine-UniversitäT DüSseldorf

Curated by ChEMBL
LigandPNGBDBM50241939(Atractylenolide I | CHEMBL449520)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed