Compile Data Set for Download or QSAR
maximum 50k data
Found 25 Enz. Inhib. hit(s) with all data for entry = 50007531
TargetNeutrophil collagenase(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064345((3S,5R,14S)-3-(2-Biphenyl-4-yl-ethyl)-14-methylcar...)
Affinity DataKi:  9nMAssay Description:Inhibition of Matrix metalloproteinase-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064346((8R,10S,13S)-13-Methylcarbamoyl-5,11,16-trioxo-10-...)
Affinity DataKi:  10nMAssay Description:Inhibition of Matrix metalloproteinase-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064344((3S,5R,14S)-14-(methylcarbamoyl)-2,8-dioxo-3-phene...)
Affinity DataKi:  17nMAssay Description:Inhibition of Matrix metalloproteinase-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064346((8R,10S,13S)-13-Methylcarbamoyl-5,11,16-trioxo-10-...)
Affinity DataKi:  238nMAssay Description:Inhibition of Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064345((3S,5R,14S)-3-(2-Biphenyl-4-yl-ethyl)-14-methylcar...)
Affinity DataKi:  249nMAssay Description:Inhibition of Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064345((3S,5R,14S)-3-(2-Biphenyl-4-yl-ethyl)-14-methylcar...)
Affinity DataKi:  288nMAssay Description:Inhibition of Matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064342((R)-2-[(S)-1-((S)-5-Acetylamino-1-methylcarbamoyl-...)
Affinity DataKi:  293nMAssay Description:Inhibition of Matrix metalloproteinase-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064342((R)-2-[(S)-1-((S)-5-Acetylamino-1-methylcarbamoyl-...)
Affinity DataKi:  404nMAssay Description:Inhibition of Matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064343((3S,5R,13S)-13-Methylcarbamoyl-2,7-dioxo-3-pheneth...)
Affinity DataKi:  531nMAssay Description:Inhibition of Matrix metalloproteinase-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064343((3S,5R,13S)-13-Methylcarbamoyl-2,7-dioxo-3-pheneth...)
Affinity DataKi:  900nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064345((3S,5R,14S)-3-(2-Biphenyl-4-yl-ethyl)-14-methylcar...)
Affinity DataKi:  1.45E+3nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064342((R)-2-[(S)-1-((S)-5-Acetylamino-1-methylcarbamoyl-...)
Affinity DataKi:  1.53E+3nMAssay Description:Inhibition of Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064343((3S,5R,13S)-13-Methylcarbamoyl-2,7-dioxo-3-pheneth...)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition of Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064345((3S,5R,14S)-3-(2-Biphenyl-4-yl-ethyl)-14-methylcar...)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition of Matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064344((3S,5R,14S)-14-(methylcarbamoyl)-2,8-dioxo-3-phene...)
Affinity DataKi:  2.50E+3nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064342((R)-2-[(S)-1-((S)-5-Acetylamino-1-methylcarbamoyl-...)
Affinity DataKi:  2.86E+3nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064346((8R,10S,13S)-13-Methylcarbamoyl-5,11,16-trioxo-10-...)
Affinity DataKi:  2.90E+3nMAssay Description:Inhibition of Matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064346((8R,10S,13S)-13-Methylcarbamoyl-5,11,16-trioxo-10-...)
Affinity DataKi:  5.80E+3nMAssay Description:Inhibition of Matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064344((3S,5R,14S)-14-(methylcarbamoyl)-2,8-dioxo-3-phene...)
Affinity DataKi:  6.60E+3nMAssay Description:Inhibition of Matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064344((3S,5R,14S)-14-(methylcarbamoyl)-2,8-dioxo-3-phene...)
Affinity DataKi:  8.10E+3nMAssay Description:Inhibition of Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064346((8R,10S,13S)-13-Methylcarbamoyl-5,11,16-trioxo-10-...)
Affinity DataKi:  8.40E+3nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064343((3S,5R,13S)-13-Methylcarbamoyl-2,7-dioxo-3-pheneth...)
Affinity DataKi:  9.80E+3nMAssay Description:Inhibition of Matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064344((3S,5R,14S)-14-(methylcarbamoyl)-2,8-dioxo-3-phene...)
Affinity DataKi:  1.35E+4nMAssay Description:Inhibition of Matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064342((R)-2-[(S)-1-((S)-5-Acetylamino-1-methylcarbamoyl-...)
Affinity DataKi:  1.41E+4nMAssay Description:Inhibition of Matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064343((3S,5R,13S)-13-Methylcarbamoyl-2,7-dioxo-3-pheneth...)
Affinity DataKi:  3.50E+4nMAssay Description:Inhibition of Matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed