Compile Data Set for Download or QSAR
maximum 50k data
Found 47 Enz. Inhib. hit(s) with all data for entry = 50007834
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM85093(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)
Affinity DataKi:  0.430nMAssay Description:In vitro binding affinity was measured at the cloned human Dopamine receptor D4.2 using [3H]-YM-09151-2 as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50048233(1-(2-Methoxy-phenyl)-4-(1-phenyl-1H-pyrrol-3-ylmet...)
Affinity DataKi:  0.700nMAssay Description:In vitro binding affinity was measured at the cloned human Dopamine receptor D4.2 using [3H]-YM-09151-2 as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50048233(1-(2-Methoxy-phenyl)-4-(1-phenyl-1H-pyrrol-3-ylmet...)
Affinity DataKi:  1.30nMAssay Description:In vitro binding affinity was measured at the cloned human Dopamine receptor D2 using [3H]-spiroperidol as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50068365((2H-Benzo[1,4]oxazin-3-yl)-{2-[4-(2-methoxy-phenyl...)
Affinity DataKi:  3nMAssay Description:In vitro binding affinity was measured at the cloned human Dopamine receptor D4.2 using [3H]-YM-09151-2 as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50068367(CHEMBL283353 | N-{2-[4-(4-Chloro-phenyl)-piperazin...)
Affinity DataKi:  8nMAssay Description:In vitro binding affinity was measured at the cloned human Dopamine receptor D4.2 using [3H]-YM-09151-2 as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50068365((2H-Benzo[1,4]oxazin-3-yl)-{2-[4-(2-methoxy-phenyl...)
Affinity DataKi:  280nMAssay Description:In vitro binding affinity was measured at the cloned human Dopamine receptor D2 using [3H]-spiroperidol as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM85093(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)
Affinity DataKi:  920nMAssay Description:In vitro binding affinity was measured at the cloned human Dopamine receptor D2 using [3H]-spiroperidol as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50068367(CHEMBL283353 | N-{2-[4-(4-Chloro-phenyl)-piperazin...)
Affinity DataKi:  2.52E+3nMAssay Description:In vitro binding affinity was measured at the cloned human Dopamine receptor D2 using [3H]-spiroperidol as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50068366(CHEMBL93403 | N-{2-[4-(4-Chloro-phenyl)-piperazin-...)
Affinity DataIC50:  0.0570nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D4.2 by [3H]-YM-09151-2 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universitá

Curated by ChEMBL
LigandPNGBDBM50068362(3-Methoxy-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-y...)
Affinity DataIC50:  0.0900nMAssay Description:Binding affinity was measured at the serotonin 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand in rat hippocampal membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50068369(3-Methoxy-N-[2-(4-pyridin-2-yl-piperazin-1-yl)-eth...)
Affinity DataIC50:  1nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D4.2 by [3H]-YM-09151-2 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50068362(3-Methoxy-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-y...)
Affinity DataIC50:  1nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D4.2 by [3H]-YM-09151-2 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50:  1.30nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D4.2 by [3H]-YM-09151-2 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50068374(3-Methoxy-N-{3-[4-(2-methoxy-phenyl)-piperazin-1-y...)
Affinity DataIC50:  2.80nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D4.2 by [3H]-YM-09151-2 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50068364(1-(3-Methoxy-phenyl)-4-[4-(2-methoxy-phenyl)-piper...)
Affinity DataIC50:  3.10nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D4.2 by [3H]-YM-09151-2 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50068361(2-Methoxy-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-y...)
Affinity DataIC50:  4nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D4.2 by [3H]-YM-09151-2 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50:  4.10nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D2 by [3H]-spiroperidol displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(4) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50068377(2,5-Dimethoxy-N-{2-[4-(2-methoxy-phenyl)-piperazin...)
Affinity DataIC50:  7.80nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D4.2 by [3H]-YM-09151-2 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50068364(1-(3-Methoxy-phenyl)-4-[4-(2-methoxy-phenyl)-piper...)
Affinity DataIC50:  13nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D2 by [3H]-spiroperidol displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50033839(1-(2-Methoxy-phenyl)-4-[3-(5-methoxy-1,2,3,4-tetra...)
Affinity DataIC50:  20nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D2 by [3H]-spiroperidol displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataIC50:  23nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D4.2 by [3H]-YM-09151-2 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(4) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50068363(3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-N-(7-metho...)
Affinity DataIC50:  30nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D4.2 by [3H]-YM-09151-2 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50068363(3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-N-(7-metho...)
Affinity DataIC50:  30nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D2 by [3H]-spiroperidol displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50068373(3-Methoxy-N-{2-[4-(2-methoxy-benzyl)-piperazin-1-y...)
Affinity DataIC50:  30nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D4.2 by [3H]-YM-09151-2 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universitá

Curated by ChEMBL
LigandPNGBDBM50068369(3-Methoxy-N-[2-(4-pyridin-2-yl-piperazin-1-yl)-eth...)
Affinity DataIC50:  30nMAssay Description:Binding affinity was measured at the serotonin 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand in rat hippocampal membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50033839(1-(2-Methoxy-phenyl)-4-[3-(5-methoxy-1,2,3,4-tetra...)
Affinity DataIC50:  60nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D4.2 by [3H]-YM-09151-2 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50068368(CHEMBL2373207 | N-{2-[4-(4-Chloro-benzyl)-piperazi...)
Affinity DataIC50:  70nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D4.2 by [3H]-YM-09151-2 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50068371(3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-N-(5-metho...)
Affinity DataIC50:  120nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D4.2 by [3H]-YM-09151-2 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50033858(1-(2-Methoxy-phenyl)-4-[3-(7-methoxy-1,2,3,4-tetra...)
Affinity DataIC50:  150nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D2 by [3H]-spiroperidol displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universitá

Curated by ChEMBL
LigandPNGBDBM50068366(CHEMBL93403 | N-{2-[4-(4-Chloro-phenyl)-piperazin-...)
Affinity DataIC50:  220nMAssay Description:Binding affinity was measured at the serotonin 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand in rat hippocampal membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataIC50:  230nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D2 by [3H]-spiroperidol displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(2) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50068377(2,5-Dimethoxy-N-{2-[4-(2-methoxy-phenyl)-piperazin...)
Affinity DataIC50:  250nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D2 by [3H]-spiroperidol displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50033858(1-(2-Methoxy-phenyl)-4-[3-(7-methoxy-1,2,3,4-tetra...)
Affinity DataIC50:  280nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D4.2 by [3H]-YM-09151-2 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50068372(2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-N-(7-metho...)
Affinity DataIC50:  470nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D4.2 by [3H]-YM-09151-2 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50068362(3-Methoxy-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-y...)
Affinity DataIC50:  700nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D2 by [3H]-spiroperidol displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50068370(1-(2-Methoxy-phenyl)-4-[4-(3-methoxy-phenyl)-thiaz...)
Affinity DataIC50:  740nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D4.2 by [3H]-YM-09151-2 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50068371(3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-N-(5-metho...)
Affinity DataIC50:  761nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D2 by [3H]-spiroperidol displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50068361(2-Methoxy-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-y...)
Affinity DataIC50:  810nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D2 by [3H]-spiroperidol displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50068376(2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-N-(5-metho...)
Affinity DataIC50:  850nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D4.2 by [3H]-YM-09151-2 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50068375(1-(2-Methoxy-phenyl)-4-{2-[4-(3-methoxy-phenyl)-th...)
Affinity DataIC50:  870nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D4.2 by [3H]-YM-09151-2 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50068375(1-(2-Methoxy-phenyl)-4-{2-[4-(3-methoxy-phenyl)-th...)
Affinity DataIC50:  870nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D2 by [3H]-spiroperidol displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50068366(CHEMBL93403 | N-{2-[4-(4-Chloro-phenyl)-piperazin-...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D2 by [3H]-spiroperidol displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50068370(1-(2-Methoxy-phenyl)-4-[4-(3-methoxy-phenyl)-thiaz...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D2 by [3H]-spiroperidol displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50068369(3-Methoxy-N-[2-(4-pyridin-2-yl-piperazin-1-yl)-eth...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D2 by [3H]-spiroperidol displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50068373(3-Methoxy-N-{2-[4-(2-methoxy-benzyl)-piperazin-1-y...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D2 by [3H]-spiroperidol displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50068374(3-Methoxy-N-{3-[4-(2-methoxy-phenyl)-piperazin-1-y...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D2 by [3H]-spiroperidol displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50068368(CHEMBL2373207 | N-{2-[4-(4-Chloro-benzyl)-piperazi...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D2 by [3H]-spiroperidol displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed