Compile Data Set for Download or QSAR
maximum 50k data
Found 30 Enz. Inhib. hit(s) with all data for entry = 50007882
TargetCaspase-1(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50068972((S)-3-(2-{3-[(Naphthalene-2-carbonyl)-amino]-2-oxo...)
Affinity DataKi:  0.370nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50068954((S)-5-Butylamino-3-(2-{3-[(naphthalene-2-carbonyl)...)
Affinity DataKi:  0.760nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50068949((S)-5-Hexylamino-3-(2-{3-[(naphthalene-2-carbonyl)...)
Affinity DataKi:  0.850nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50068950((S)-3-(2-{3-[(Naphthalene-2-carbonyl)-amino]-2-oxo...)
Affinity DataKi:  1.20nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50068945((S)-5-(Hexyl-methyl-amino)-3-(2-{3-[(naphthalene-2...)
Affinity DataKi:  1.80nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50068953((S)-5-(Butyl-ethyl-amino)-3-(2-{3-[(naphthalene-2-...)
Affinity DataKi:  2.30nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50068951((S)-5-Dihexylamino-3-(2-{3-[(naphthalene-2-carbony...)
Affinity DataKi:  2.40nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50068962((S)-5-(Butyl-methyl-amino)-3-(2-{3-[(naphthalene-2...)
Affinity DataKi:  3.10nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50068957((S)-5-Benzylamino-3-(2-{3-[(naphthalene-2-carbonyl...)
Affinity DataKi:  3.10nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50068967(3-(2-{3-[(Naphthalene-2-carbonyl)-amino]-2-oxo-2H-...)
Affinity DataKi:  4nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50068966((S)-5-(Methyl-phenethyl-amino)-3-(2-{3-[(naphthale...)
Affinity DataKi:  4.80nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50068965(3-(2-{3-[(Naphthalene-2-carbonyl)-amino]-2-oxo-2H-...)
Affinity DataKi:  7.30nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50068952(1-[4-Carboxy-3-(2-{3-[(naphthalene-2-carbonyl)-ami...)
Affinity DataKi:  8nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50068955(3-(2-{3-[(Naphthalene-2-carbonyl)-amino]-2-oxo-2H-...)
Affinity DataKi:  11nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50068971(5-(4-Carbamoyl-piperidin-1-yl)-3-(2-{3-[(naphthale...)
Affinity DataKi:  12nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50068970((S)-5-Dimethylamino-3-(2-{3-[(naphthalene-2-carbon...)
Affinity DataKi:  23nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50068969((S)-5-((R)-1-Carbamoyl-2-phenyl-ethylamino)-3-(2-{...)
Affinity DataKi:  25nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50068973(5-Hexanoylamino-3-(2-{3-[(naphthalene-2-carbonyl)-...)
Affinity DataKi:  34nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50068947((S)-5-[(3-Carbamoyl-propyl)-methyl-amino]-3-(2-{3-...)
Affinity DataKi:  37nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50068944(5-Morpholin-4-yl-3-(2-{3-[(naphthalene-2-carbonyl)...)
Affinity DataKi:  45nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50068946((S)-5-(Benzyl-methyl-amino)-3-(2-{3-[(naphthalene-...)
Affinity DataKi:  58nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50068968(5-Benzoylamino-3-(2-{3-[(naphthalene-2-carbonyl)-a...)
Affinity DataKi:  58nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50068958(5-(4-Methyl-piperazin-1-yl)-3-(2-{3-[(naphthalene-...)
Affinity DataKi:  63nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50068960((S)-5-((S)-1-Carbamoyl-2-phenyl-ethylamino)-3-(2-{...)
Affinity DataKi:  78nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50068948(5-Butyrylamino-3-(2-{3-[(naphthalene-2-carbonyl)-a...)
Affinity DataKi:  81nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50068963(5-Acetylamino-3-(2-{3-[(naphthalene-2-carbonyl)-am...)
Affinity DataKi:  117nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50068959((S)-5-[((S)-1-Carbamoyl-2-phenyl-ethyl)-methyl-ami...)
Affinity DataKi:  255nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50068961(3-(2-{3-[(Naphthalene-2-carbonyl)-amino]-2-oxo-2H-...)
Affinity DataKi:  395nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50068964(3-(2-{3-[(Naphthalene-2-carbonyl)-amino]-2-oxo-2H-...)
Affinity DataKi:  410nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50068956(3-(2-{3-[(Naphthalene-2-carbonyl)-amino]-2-oxo-2H-...)
Affinity DataKi:  1.65E+3nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed