Compile Data Set for Download or QSAR
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Found 19 Enz. Inhib. hit(s) with all data for entry = 50034976
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50069998(Ammonium; [7-(difluoro-phosphono-methyl)-naphthale...)
Affinity DataKi:  9.00E+3nMAssay Description:Compound was evaluated for inhibitory constant against CD45More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50069997(Ammonium; [7-(difluoro-phosphono-methyl)-naphthale...)
Affinity DataKi:  1.60E+4nMAssay Description:Compound was evaluated for inhibitory constant against PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50070004(difluoro(4-hydroxy-2-naphthyl)methylphosphonate)
Affinity DataKi:  9.30E+4nMAssay Description:Compound was evaluated for inhibitory constant against PTP1BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50075312((Difluoro-naphthalen-2-yl-methyl)-phosphonic acid ...)
Affinity DataKi:  1.97E+5nMAssay Description:Compound was evaluated for inhibitory constant against PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50070001(difluoro(1-naphthyl)methylphosphonate)
Affinity DataKi:  2.55E+5nMAssay Description:Compound was evaluated for inhibitory constant against PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50069997(Ammonium; [7-(difluoro-phosphono-methyl)-naphthale...)
Affinity DataIC50:  2.60E+4nMAssay Description:Compound was evaluated for 50% inhibition of PTP1B using uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50069998(Ammonium; [7-(difluoro-phosphono-methyl)-naphthale...)
Affinity DataIC50:  2.70E+4nMAssay Description:Compound was evaluated for 50% inhibition of CD45 using uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50070003(Ammonium; [6-(difluoro-phosphono-methyl)-naphthale...)
Affinity DataIC50:  2.90E+4nMAssay Description:Compound was evaluated for 50% inhibition of PTP1B using uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50075312((Difluoro-naphthalen-2-yl-methyl)-phosphonic acid ...)
Affinity DataIC50:  9.50E+4nMAssay Description:Compound was evaluated for 50% inhibition of PTP1B using uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50070003(Ammonium; [6-(difluoro-phosphono-methyl)-naphthale...)
Affinity DataIC50: >1.00E+5nMAssay Description:Compound was evaluated for 50% inhibition of CD45 protein-tyrosine phosphatase using uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50070001(difluoro(1-naphthyl)methylphosphonate)
Affinity DataIC50:  1.12E+5nMAssay Description:Compound was evaluated for 50% inhibition of PTP1B using uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50069998(Ammonium; [7-(difluoro-phosphono-methyl)-naphthale...)
Affinity DataIC50:  1.18E+5nMAssay Description:Compound was evaluated for 50% inhibition of PTP1B using uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50070000(fluoro{7-[fluoro(phosphonato)methyl]-2-naphthyl}me...)
Affinity DataIC50:  1.30E+5nMAssay Description:Compound was evaluated for 50% inhibition of PTP1B using uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50069997(Ammonium; [7-(difluoro-phosphono-methyl)-naphthale...)
Affinity DataIC50:  1.80E+5nMAssay Description:Compound was evaluated for 50% inhibition of CD45 using uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50070000(fluoro{7-[fluoro(phosphonato)methyl]-2-naphthyl}me...)
Affinity DataIC50:  2.79E+5nMAssay Description:Compound was evaluated for 50% inhibition of CD45 protein-tyrosine phosphatase using uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50070002([7-(phosphonatomethyl)-2-naphthyl]methylphosphonat...)
Affinity DataIC50:  5.00E+5nMAssay Description:Compound was evaluated for 50% inhibition of CD45 protein-tyrosine phosphatase using uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50070002([7-(phosphonatomethyl)-2-naphthyl]methylphosphonat...)
Affinity DataIC50: >5.00E+5nMAssay Description:Compound was evaluated for 50% inhibition of PTP1B using uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50075312((Difluoro-naphthalen-2-yl-methyl)-phosphonic acid ...)
Affinity DataIC50: >1.00E+6nMAssay Description:Compound was evaluated for 50% inhibition of CD45 using uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50070001(difluoro(1-naphthyl)methylphosphonate)
Affinity DataIC50: >1.00E+6nMAssay Description:Compound was evaluated for 50% inhibition of CD45 using uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed