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Found 14 Enz. Inhib. hit(s) with all data for entry = 50048445
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50216304(CHEMBL313439)
Affinity DataIC50:  130nMAssay Description:Inhibition of PDE4 enzyme from U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50216301(CHEMBL88475)
Affinity DataIC50:  230nMAssay Description:Inhibition of PDE4 enzyme from U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50216299(CHEMBL315529)
Affinity DataIC50:  350nMAssay Description:Inhibition of PDE4 enzyme from U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)
Affinity DataIC50:  400nMAssay Description:Inhibition of phosphodiesterase 4 from U937 cellsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50216303(CHEMBL90349)
Affinity DataIC50:  740nMAssay Description:Inhibition of PDE4 enzyme from U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50216298(CC-1088 | CHEMBL88153)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of PDE4 enzyme from U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50216295(CHEMBL314759)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of PDE4 enzyme from U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50216300(CHEMBL90345)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of PDE4 enzyme from U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50216302(CHEMBL419135)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of PDE4 enzyme from U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50216296(CHEMBL89635)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of phosphodiesterase 4 from U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50052596(3-(3,4-Dimethoxy-phenyl)-3-(1,3-dioxo-1,3-dihydro-...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of PDE4 enzyme from U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50216305(CHEMBL275009)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of phosphodiesterase 4 from U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50052599(3-(3,4-Dimethoxy-phenyl)-3-(1,3-dioxo-1,3-dihydro-...)
Affinity DataIC50:  9.40E+3nMAssay Description:Inhibition of PDE4 enzyme from U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50070114((+/-)-thalidomide | 2-(2,6-Dioxo-piperidin-3-yl)-i...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of PDE4 enzyme from U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed