Compile Data Set for Download or QSAR
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Found 14 Enz. Inhib. hit(s) with all data for entry = 50008383
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50072869(CHEMBL331463 | Phosphoric acid mono-{4-[(S)-2-acet...)
Affinity DataIC50:  11nMAssay Description:Inhibition of Grb2 SH2 domain bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50072862(CHEMBL117807 | Phosphoric acid mono-[4-((S)-2-acet...)
Affinity DataIC50:  70nMAssay Description:Inhibition of Grb2 SH2 domain binding by surface plasmon resonanceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50072864(CHEMBL115699 | {[4-((S)-2-Acetylamino-2-{1-[(S)-2-...)
Affinity DataIC50:  80nMAssay Description:Inhibition of Growth factor receptor bound protein 2 SH2 domain binding in plasmon resonance binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50072861(CHEMBL19417 | [(S)-4-(2-Acetylamino-2-{1-[2-carbam...)
Affinity DataIC50:  80nMAssay Description:Inhibition of Growth factor receptor bound protein 2 SH2 domain binding in plasmon resonance binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50072861(CHEMBL19417 | [(S)-4-(2-Acetylamino-2-{1-[2-carbam...)
Affinity DataIC50:  80nMAssay Description:Inhibition of Growth factor receptor bound protein 2 SH2 domain binding in plasmon resonance binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50072866(CHEMBL2370501 | Phosphoric acid mono-[4-((4R,7S,10...)
Affinity DataIC50:  370nMAssay Description:Inhibition of Grb2 SH2 domain bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50072865(CHEMBL55627 | N-[(S)-1-{1-[(S)-2-Carbamoyl-1-(3-na...)
Affinity DataIC50:  500nMAssay Description:Inhibition of Grb2 SH2 domain binding in MDA-MB-453 human breast carcinoma cell lysatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50072864(CHEMBL115699 | {[4-((S)-2-Acetylamino-2-{1-[(S)-2-...)
Affinity DataIC50:  500nMAssay Description:Inhibition of Grb2 SH2 domain binding in MDA-MB-453 human breast carcinoma cell lysatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50072868(5-[(S)-2-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-...)
Affinity DataIC50:  500nMAssay Description:Inhibition of Grb2 SH2 domain binding in MDA-MB-453 human breast carcinoma cell lysatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50072860(Asp-Asp-Pro-Ser-pTyr-Val-Asn-Val-Gln | CHEMBL41223...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of Grb2 SH2 domain bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50072868(5-[(S)-2-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of Growth factor receptor bound protein 2 SH2 domain binding in plasmon resonance binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50072867(5-((S)-2-Acetylamino-2-{1-[(S)-2-carbamoyl-1-(3-na...)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of Growth factor receptor bound protein 2 SH2 domain binding in plasmon resonance binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50072863((S)-2-({1-[(S)-2-Acetylamino-3-(4-hydroxy-phenyl)-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Grb2 SH2 domain binding in MDA-MB-453 human breast carcinoma cell lysatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50072870(CHEMBL332124 | [4-((S)-2-Acetylamino-2-{1-[(S)-2-c...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Growth factor receptor bound protein 2 SH2 domain binding in plasmon resonance binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed