Compile Data Set for Download or QSAR
maximum 50k data
Found 51 Enz. Inhib. hit(s) with all data for entry = 50008475
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50073700((R)-2-Hexyl-7-isopropyl-5-methyl-7,8-dihydro-3H,5H...)
Affinity DataIC50:  5nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific Phosphodiesterase 5 (PDE5) of bovine lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50073694((R)-7-Isopropyl-5-methyl-2-(4-methyl-pentyl)-7,8-d...)
Affinity DataIC50:  6nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific Phosphodiesterase 5 (PDE5) of bovine lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50073692(5-methyl-2-(4-methylpentyl)-(6aR,9aS)-3,4,5,8-tetr...)
Affinity DataIC50:  6nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50073703(2-Hexyl-5,7,7-trimethyl-7,8-dihydro-3H,5H-imidazo[...)
Affinity DataIC50:  8nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific Phosphodiesterase 5 (PDE5) of bovine lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50059062((6aR,9aS)-2-Hexyl-5,6a,7,8,9,9a-hexahydro-5-methyl...)
Affinity DataIC50:  10nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific Phosphodiesterase 5 (PDE5) of bovine lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50073692(5-methyl-2-(4-methylpentyl)-(6aR,9aS)-3,4,5,8-tetr...)
Affinity DataIC50:  10nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific Phosphodiesterase 5 (PDE5) of bovine lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50073701(2'-hexyl-5'-methylspiro[cyclopentane-1,7'-(4',5',7...)
Affinity DataIC50:  11nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific Phosphodiesterase 5 (PDE5) of bovine lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50073694((R)-7-Isopropyl-5-methyl-2-(4-methyl-pentyl)-7,8-d...)
Affinity DataIC50:  12nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50073702(2-heptyl-5-methyl-(6aR,9aS)-3,4,5,8-tetrahydrocycl...)
Affinity DataIC50:  14nMAssay Description:Inhibition of c-GMP specific phosphodiesterase PDE5 of bovine lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50059032((6aR,9aS)-2-(3-methylbutyl)-5,6a,7,8,9,9a-hexahydr...)
Affinity DataIC50:  14nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50073701(2'-hexyl-5'-methylspiro[cyclopentane-1,7'-(4',5',7...)
Affinity DataIC50:  14nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50073695((R)-7-Isopropyl-5-methyl-2-(3-methyl-butyl)-7,8-di...)
Affinity DataIC50:  15nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50073695((R)-7-Isopropyl-5-methyl-2-(3-methyl-butyl)-7,8-di...)
Affinity DataIC50:  22nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific Phosphodiesterase 5 (PDE5) of bovine lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50073700((R)-2-Hexyl-7-isopropyl-5-methyl-7,8-dihydro-3H,5H...)
Affinity DataIC50:  25nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50073703(2-Hexyl-5,7,7-trimethyl-7,8-dihydro-3H,5H-imidazo[...)
Affinity DataIC50:  25nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50073698(5-methyl-2-octyl-(6aR,9aS)-3,4,5,8-tetrahydrocyclo...)
Affinity DataIC50:  30nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific Phosphodiesterase 5 (PDE5) of bovine lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50073696(5-methyl-2-pentyl-(6aR,9aS)-3,4,5,8-tetrahydrocycl...)
Affinity DataIC50:  31nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50073702(2-heptyl-5-methyl-(6aR,9aS)-3,4,5,8-tetrahydrocycl...)
Affinity DataIC50:  33nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50059062((6aR,9aS)-2-Hexyl-5,6a,7,8,9,9a-hexahydro-5-methyl...)
Affinity DataIC50:  36nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50073696(5-methyl-2-pentyl-(6aR,9aS)-3,4,5,8-tetrahydrocycl...)
Affinity DataIC50:  40nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific Phosphodiesterase 5 (PDE5) of bovine lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50059032((6aR,9aS)-2-(3-methylbutyl)-5,6a,7,8,9,9a-hexahydr...)
Affinity DataIC50:  50nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific Phosphodiesterase 5 (PDE5) of bovine lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50073697(5-methyl-2-(1-propylbutyl)-(6aR,9aS)-3,4,5,8-tetra...)
Affinity DataIC50:  60nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50073704(2-butyl-5-methyl-(6aR,9aS)-3,4,5,8-tetrahydrocyclo...)
Affinity DataIC50:  110nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50073704(2-butyl-5-methyl-(6aR,9aS)-3,4,5,8-tetrahydrocyclo...)
Affinity DataIC50:  140nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific Phosphodiesterase 5 (PDE5) of bovine lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50073697(5-methyl-2-(1-propylbutyl)-(6aR,9aS)-3,4,5,8-tetra...)
Affinity DataIC50:  150nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific Phosphodiesterase 5 (PDE5) of bovine lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50073693(2-(1-ethylpropyl)-5-methyl-(6aR,9aS)-3,4,5,8-tetra...)
Affinity DataIC50:  150nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50073698(5-methyl-2-octyl-(6aR,9aS)-3,4,5,8-tetrahydrocyclo...)
Affinity DataIC50:  160nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50073699(2-ethyl-5-methyl-(6aR,9aS)-3,4,5,8-tetrahydrocyclo...)
Affinity DataIC50:  295nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50059047((6aR,9aS)-2-Propyl-5,6a,7,8,9,9a-hexahydro-5-methy...)
Affinity DataIC50:  350nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50059047((6aR,9aS)-2-Propyl-5,6a,7,8,9,9a-hexahydro-5-methy...)
Affinity DataIC50:  800nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific Phosphodiesterase 5 (PDE5) of bovine lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50073699(2-ethyl-5-methyl-(6aR,9aS)-3,4,5,8-tetrahydrocyclo...)
Affinity DataIC50:  1.20E+3nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific Phosphodiesterase 5 (PDE5) of bovine lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50059028((6aR,9aS)-5,6a,7,8,9,9a-Hexahydro-2,5-dimethyl-cyc...)
Affinity DataIC50:  1.25E+3nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50073693(2-(1-ethylpropyl)-5-methyl-(6aR,9aS)-3,4,5,8-tetra...)
Affinity DataIC50:  1.40E+3nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific Phosphodiesterase 5 (PDE5) of bovine lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50059028((6aR,9aS)-5,6a,7,8,9,9a-Hexahydro-2,5-dimethyl-cyc...)
Affinity DataIC50:  2.40E+3nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific Phosphodiesterase 5 (PDE5) of bovine lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50073698(5-methyl-2-octyl-(6aR,9aS)-3,4,5,8-tetrahydrocyclo...)
Affinity DataIC50:  7.00E+3nMAssay Description:Optimum inhibitory concentration required to inhibit cGMP specific phosphodiesterase 3 (PDE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50073702(2-heptyl-5-methyl-(6aR,9aS)-3,4,5,8-tetrahydrocycl...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of cGMP-inhibited phosphodiesterase 3 (PDE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50059062((6aR,9aS)-2-Hexyl-5,6a,7,8,9,9a-hexahydro-5-methyl...)
Affinity DataIC50:  1.20E+4nMAssay Description:Optimum inhibitory concentration required to inhibit cGMP specific phosphodiesterase 3 (PDE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50059032((6aR,9aS)-2-(3-methylbutyl)-5,6a,7,8,9,9a-hexahydr...)
Affinity DataIC50:  1.50E+4nMAssay Description:Optimum inhibitory concentration required to inhibit cGMP specific phosphodiesterase 3 (PDE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50073701(2'-hexyl-5'-methylspiro[cyclopentane-1,7'-(4',5',7...)
Affinity DataIC50:  1.50E+4nMAssay Description:Optimum inhibitory concentration required to inhibit cGMP specific phosphodiesterase 3 (PDE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50073700((R)-2-Hexyl-7-isopropyl-5-methyl-7,8-dihydro-3H,5H...)
Affinity DataIC50:  1.80E+4nMAssay Description:Optimum inhibitory concentration required to inhibit cGMP specific phosphodiesterase 3 (PDE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50073696(5-methyl-2-pentyl-(6aR,9aS)-3,4,5,8-tetrahydrocycl...)
Affinity DataIC50:  2.00E+4nMAssay Description:Optimum inhibitory concentration required to inhibit cGMP specific phosphodiesterase 3 (PDE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50073703(2-Hexyl-5,7,7-trimethyl-7,8-dihydro-3H,5H-imidazo[...)
Affinity DataIC50:  2.80E+4nMAssay Description:Optimum inhibitory concentration required to inhibit cGMP specific phosphodiesterase 3 (PDE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50073692(5-methyl-2-(4-methylpentyl)-(6aR,9aS)-3,4,5,8-tetr...)
Affinity DataIC50:  3.50E+4nMAssay Description:Optimum inhibitory concentration required to inhibit cGMP specific phosphodiesterase 3 (PDE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50073704(2-butyl-5-methyl-(6aR,9aS)-3,4,5,8-tetrahydrocyclo...)
Affinity DataIC50:  3.80E+4nMAssay Description:Optimum inhibitory concentration required to inhibit cGMP specific phosphodiesterase 3 (PDE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50073695((R)-7-Isopropyl-5-methyl-2-(3-methyl-butyl)-7,8-di...)
Affinity DataIC50:  4.00E+4nMAssay Description:Optimum inhibitory concentration required to inhibit cGMP specific phosphodiesterase 3 (PDE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50073694((R)-7-Isopropyl-5-methyl-2-(4-methyl-pentyl)-7,8-d...)
Affinity DataIC50:  6.50E+4nMAssay Description:Optimum inhibitory concentration required to inhibit cGMP specific phosphodiesterase 3 (PDE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50073697(5-methyl-2-(1-propylbutyl)-(6aR,9aS)-3,4,5,8-tetra...)
Affinity DataIC50:  8.00E+4nMAssay Description:Optimum inhibitory concentration required to inhibit cGMP specific phosphodiesterase 3 (PDE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50059047((6aR,9aS)-2-Propyl-5,6a,7,8,9,9a-hexahydro-5-methy...)
Affinity DataIC50:  8.00E+4nMAssay Description:Optimum inhibitory concentration required to inhibit cGMP specific phosphodiesterase 3 (PDE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50073699(2-ethyl-5-methyl-(6aR,9aS)-3,4,5,8-tetrahydrocyclo...)
Affinity DataIC50:  1.50E+5nMAssay Description:Optimum inhibitory concentration required to inhibit cGMP specific phosphodiesterase 3 (PDE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50073693(2-(1-ethylpropyl)-5-methyl-(6aR,9aS)-3,4,5,8-tetra...)
Affinity DataIC50:  1.50E+5nMAssay Description:Optimum inhibitory concentration required to inhibit cGMP specific phosphodiesterase 3 (PDE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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