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maximum 50k data
Found 79 Enz. Inhib. hit(s) with all data for entry = 6412
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127573(US8791100, 71)
Affinity DataIC50:  0.100nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127560(US8791100, 58)
Affinity DataIC50:  0.100nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127572(US8791100, 70)
Affinity DataIC50:  0.100nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127506(US8791100, 4)
Affinity DataIC50:  0.200nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127567(US8791100, 65)
Affinity DataIC50:  0.200nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127531(US8791100, 29)
Affinity DataIC50:  0.400nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127586(US8791100, 84)
Affinity DataIC50:  0.400nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127542(US8791100, 40)
Affinity DataIC50:  0.400nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127511(US8791100, 9)
Affinity DataIC50:  0.400nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127557(US8791100, 55)
Affinity DataIC50:  0.5nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127508(US8791100, 6)
Affinity DataIC50:  0.5nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127581(US8791100, 79)
Affinity DataIC50:  0.600nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127535(US8791100, 33)
Affinity DataIC50:  0.600nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127588(US8791100, 86 | US8791100, 87)
Affinity DataIC50:  0.700nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127570(US8791100, 68)
Affinity DataIC50:  0.700nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127571(US8791100, 69)
Affinity DataIC50:  0.800nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127569(US8791100, 67)
Affinity DataIC50:  0.800nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127545(US8791100, 43)
Affinity DataIC50:  0.800nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127540(US8791100, 38)
Affinity DataIC50:  0.800nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127536(US8791100, 34)
Affinity DataIC50:  0.800nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127534(US8791100, 32)
Affinity DataIC50:  0.800nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127530(US8791100, 28)
Affinity DataIC50:  0.800nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127580(US8791100, 78)
Affinity DataIC50:  0.800nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127524(US8791100, 22)
Affinity DataIC50:  0.800nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127541(US8791100, 39)
Affinity DataIC50:  0.800nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127587(US8791100, 85)
Affinity DataIC50:  0.900nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127564(US8791100, 62)
Affinity DataIC50:  0.900nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127556(US8791100, 54)
Affinity DataIC50:  0.900nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127532(US8791100, 30)
Affinity DataIC50:  0.900nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127505(US8791100, 3)
Affinity DataIC50:  0.900nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127554(US8791100, 52)
Affinity DataIC50:  0.900nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127523(US8791100, 21)
Affinity DataIC50:  1nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127544(US8791100, 42)
Affinity DataIC50:  1nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127533(US8791100, 31)
Affinity DataIC50:  1nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127525(US8791100, 23)
Affinity DataIC50:  1nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127574(US8791100, 72)
Affinity DataIC50:  1.10nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127565(US8791100, 63)
Affinity DataIC50:  1.10nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127588(US8791100, 86 | US8791100, 87)
Affinity DataIC50:  1.20nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127509(US8791100, 7)
Affinity DataIC50:  1.20nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127575(US8791100, 73)
Affinity DataIC50:  1.20nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127568(US8791100, 66)
Affinity DataIC50:  1.20nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127561(US8791100, 59)
Affinity DataIC50:  1.20nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127550(US8791100, 48 | US8791100, 53)
Affinity DataIC50:  1.20nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127547(US8791100, 45)
Affinity DataIC50:  1.20nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127548(US8791100, 46)
Affinity DataIC50:  1.30nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127543(US8791100, 41)
Affinity DataIC50:  1.30nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127516(US8791100, 14)
Affinity DataIC50:  1.5nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127510(US8791100, 8)
Affinity DataIC50:  1.5nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127563(US8791100, 61)
Affinity DataIC50:  1.60nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM127519(US8791100, 17)
Affinity DataIC50:  1.60nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
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