Reaction Details  Report a problem with these data
Cell Reactant:
Cyclin-dependent kinase 2
Syringe Reactant:
BDBM225320
Meas. Tech.:
Enzyme Inhibition
Entry Date.:
05/10/17
ΔG°:
-38.3±0.063 (kJ/mole)
Temperature:
298±0 (K)
ΔH° :
-62.76±0.71 (kJ/mole)
ΔS° :
-0.0816±0.0023 (kJ/mole-K)
Citation
 D3R, DD CSAR CDK2 Kinase D3R 220:0 (2015) [PubMed] 
Cell React
Name:
Cyclin-dependent kinase 2
Synonyms:
CDK2 | CDK2-Kinase | CDK2_HUMAN | CDKN2 | Cell division protein kinase 2 | Cyclin-dependent kinase 2 (CDK2) | Protein cereblon/Cyclin-dependent kinase 2 | p33 protein kinase
Type:
Enzyme Subunit
Mol. Mass.:
33938.17
Organism:
Homo sapiens (Human)
Description:
P24941
Residue:
298
Sequence:
MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
  
Syringe React
Name:
BDBM225320
Synonyms:
CS246
Type:
Small Organic Molecule
Emp. Form.:
C18H13N4O4S2
Mol. Mass.:
413.451
SMILES:
CC(=O)N=S([O-])(=O)c1ccc(N\C=C2/C(=O)Nc3ccc4ncsc4c23)cc1
Structure:
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