Cell Reactant:
Fructose-1,6-bisphosphate aldolase (FBA)
Syringe Reactant:
BDBM237136
Meas. Tech.:
Enzyme Inhibition
Entry Date.:
07/10/17
ΔH° :
-28.73±0.58 (kJ/mole)
ΔS° :
2.44±3.12 (kJ/mole-K)
Citation
 Pegan, SDAhrendt, KCapodagli, GCCowen, B Antibiotic and anti-parasitic agents that modulate class II fructose 1,6-bisphosphate aldolase US Patent  US9394254 Publication Date 7/19/2016
Cell React
Name:
Fructose-bisphosphate aldolase
Synonyms:
FBP aldolase | FBPA | Fructose-1,6-bisphosphate aldolase | Fructose-1,6-bisphosphate aldolase (FBA) | Fructose-bisphosphate aldolase | Probable fructose-bisphosphate aldolase Fba
Type:
Protein
Mol. Mass.:
36539.01
Organism:
Mycobacterium tuberculosis (strain H37Rv)
Description:
P9WQA3
Residue:
344
Sequence:
MPIATPEVYAEMLGQAKQNSYAFPAINCTSSETVNAAIKGFADAGSDGIIQFSTGGAEFGSGLGVKDMVTGAVALAEFTHVIAAKYPVNVALHTDHCPKDKLDSYVRPLLAISAQRVSKGGNPLFQSHMWDGSAVPIDENLAIAQELLKAAAAAKIILEIEIGVVGGEEDGVANEINEKLYTSPEDFEKTIEALGAGEHGKYLLAATFGNVHGVYKPGNVKLRPDILAQGQQVAAAKLGLPADAKPFDFVFHGGSGSLKSEIEEALRYGVVKMNVDTDTQYAFTRPIAGHMFTNYDGVLKVDGEVGVKKVYDPRSYLKKAEASMSQRVVQACNDLHCAGKSLTH
  
Syringe React
Name:
BDBM237136
Synonyms:
US9394254, 5 (HCA)
Type:
Small organic molecule
Emp. Form.:
C10H7NO3
Mol. Mass.:
189.1675
SMILES:
OC(=O)c1ccc2cccc(O)c2n1
Structure:
Search PDB for entries with ligand similarity: