Reaction Details Report a problem with these data
Target
Sigma intracellular receptor 2
Ligand
BDBM507025
Substrate
n/a
Ki
1258±n/a nM
Citation
 Martin, SF; Sahn, JJ; Hodges, TR Piperazinyl norbenzomorphan compounds and methods for using the same US Patent  US11046670 Publication Date 6/29/2021 
Target
Name:
Sigma intracellular receptor 2
Synonyms:
MAC30 | Meningioma-associated protein 30 | S2R | SGMR2_HUMAN | Sigma-2 receptor | Sigma2 receptor | TMEM97 | Transmembrane protein 97
Type:
Protein
Mol. Mass.:
20857.20
Organism:
Homo sapiens (Human)
Description:
Q5BJF2
Residue:
176
Sequence:
MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK
  
Inhibitor
Name:
BDBM507025
Synonyms:
US11046670, Compound 40
Type:
Small organic molecule
Emp. Form.:
C22H25FN2O
Mol. Mass.:
352.4451
SMILES:
Fc1ccccc1CN1CC[C@@H]2C[C@@H]1c1cc(ccc21)N1CCOCC1 |r,TLB:18:19:10.8.9:12,7:8:19.14:12,THB:15:14:10.8.9:12|
Structure:
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