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Target
Sigma intracellular receptor 2
Ligand
BDBM507040
Substrate
n/a
Ki
16±n/a nM
Citation
 Martin, SF; Sahn, JJ; Hodges, TR Piperazinyl norbenzomorphan compounds and methods for using the same US Patent  US11046670 Publication Date 6/29/2021 
Target
Name:
Sigma intracellular receptor 2
Synonyms:
MAC30 | Meningioma-associated protein 30 | S2R | SGMR2_HUMAN | Sigma-2 receptor | Sigma2 receptor | TMEM97 | Transmembrane protein 97
Type:
Protein
Mol. Mass.:
20857.20
Organism:
Homo sapiens (Human)
Description:
Q5BJF2
Residue:
176
Sequence:
MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK
  
Inhibitor
Name:
BDBM507040
Synonyms:
US11046670, Compound 29
Type:
Small organic molecule
Emp. Form.:
C27H33N3O2
Mol. Mass.:
431.5698
SMILES:
C=CCCN1CCN(CC1)c1ccc2[C@H]3C[C@@H](N(CC3)C(=O)OCc3ccccc3)c2c1 |r,TLB:20:17:13.30:15,31:30:19.17.18:15,THB:12:13:19.17.18:15|
Structure:
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