Reaction Details Report a problem with these data
Target
Sigma intracellular receptor 2
Ligand
BDBM50232701
Substrate
n/a
Ki
4.00±n/a nM
Citation
 Martin, SF; Sahn, JJ; Hodges, TR Piperazinyl norbenzomorphan compounds and methods for using the same US Patent  US11046670 Publication Date 6/29/2021 
Target
Name:
Sigma intracellular receptor 2
Synonyms:
MAC30 | Meningioma-associated protein 30 | S2R | SGMR2_HUMAN | Sigma-2 receptor | Sigma2 receptor | TMEM97 | Transmembrane protein 97
Type:
Protein
Mol. Mass.:
20857.20
Organism:
Homo sapiens (Human)
Description:
Q5BJF2
Residue:
176
Sequence:
MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK
  
Inhibitor
Name:
BDBM50232701
Synonyms:
CHEMBL4072304 | US11046670, Table 6.1
Type:
Small organic molecule
Emp. Form.:
C26H33N3O2
Mol. Mass.:
419.5591
SMILES:
[H][C@]12C[C@@]([H])(N(CC1)C(=O)OCc1ccccc1)c1cc(ccc21)N1CCN(CCC)CC1 |r,TLB:19:18:2:5.6.7,8:5:2:23.18,THB:22:23:2:5.6.7|
Structure:
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