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Target
Galectin-3
Ligand
BDBM508750
Substrate
n/a
Meas. Tech.
fluorescence anisotropy assay
Kd
69.0±n/a nM
Citation
 Zetterberg, F Galactoside inhibitor of galectins US Patent  US11046725 Publication Date 6/29/2021 
Target
Name:
Galectin-3
Synonyms:
LEG3_HUMAN | LGALS3 | MAC2
Type:
Enzyme
Mol. Mass.:
26156.54
Organism:
Homo sapiens (Human)
Description:
P17931
Residue:
250
Sequence:
MADNFSLHDALSGSGNPNPQGWPGAWGNQPAGAGGYPGASYPGAYPGQAPPGAYPGQAPPGAYPGAPGAYPGAPAPGVYPGPPSGPGAYPSSGQPSATGAYPATGPYGAPAGPLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPRFNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVAVNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI
  
Inhibitor
Name:
BDBM508750
Synonyms:
5-Bromo-6-trifluoromethyl-pyridine-3-yl 3-deoxy-3-[4-(4,5-dichlorothiazol-2-yl)-1H-1,2,3-triazol-1-yl]-1-thio-α-D-galactopyranoside | US11046725, Example 29
Type:
Small organic molecule
Emp. Form.:
C17H13BrCl2F3N5O4S2
Mol. Mass.:
623.251
SMILES:
OCC1O[C@H](Sc2cnc(c(Br)c2)C(F)(F)F)C(O)[C@H]([C@H]1O)n1cc(nn1)-c1nc(Cl)c(Cl)s1 |r|
Structure:
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