Reaction Details Report a problem with these data
Target
Galectin-3
Ligand
BDBM508752
Substrate
n/a
Meas. Tech.
fluorescence anisotropy assay
Kd
2100±n/a nM
Citation
 Zetterberg, F Galactoside inhibitor of galectins US Patent  US11046725 Publication Date 6/29/2021 
Target
Name:
Galectin-3
Synonyms:
LEG3_HUMAN | LGALS3 | MAC2
Type:
Enzyme
Mol. Mass.:
26156.54
Organism:
Homo sapiens (Human)
Description:
P17931
Residue:
250
Sequence:
MADNFSLHDALSGSGNPNPQGWPGAWGNQPAGAGGYPGASYPGAYPGQAPPGAYPGQAPPGAYPGAPGAYPGAPAPGVYPGPPSGPGAYPSSGQPSATGAYPATGPYGAPAGPLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPRFNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVAVNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI
  
Inhibitor
Name:
BDBM508752
Synonyms:
4-Chloro-N,N′-dimethylbenzamide-2-yl 3-deoxy-3-[4-(2-hydroxythiazol-4-yl)-1H-1,2,3-triazol-1-yl]-1-thio-α-D-galactopyranoside | US11046725, Example 32
Type:
Small organic molecule
Emp. Form.:
C20H22ClN5O6S2
Mol. Mass.:
528.002
SMILES:
CN(C)C(=O)c1ccc(Cl)cc1S[C@H]1OC(CO)[C@H](O)[C@@H](C1O)n1cc(nn1)-c1csc(O)n1 |r|
Structure:
Search PDB for entries with ligand similarity: