Reaction Details Report a problem with these data
Target
Galectin-1
Ligand
BDBM508753
Substrate
n/a
Meas. Tech.
fluorescence anisotropy assay
Kd
54.0±n/a nM
Citation
 Zetterberg, F Galactoside inhibitor of galectins US Patent  US11046725 Publication Date 6/29/2021 
Target
Name:
Galectin-1
Synonyms:
14 kDa lectin | Galaptin | HPL | LEG1_HUMAN | LGALS1 | Lactose-binding lectin 1 | Lectin galactoside-binding soluble 1 | Putative MAPK-activating protein PM12
Type:
beta galactoside-binding protein
Mol. Mass.:
14713.53
Organism:
Homo sapiens (Human)
Description:
P09382
Residue:
135
Sequence:
MACGLVASNLNLKPGECLRVRGEVAPDAKSFVLNLGKDSNNLCLHFNPRFNAHGDANTIVCNSKDGGAWGTEQREAVFPFQPGSVAEVCITFDQANLTVKLPDGYEFKFPNRLNLEAINYMAADGDFKIKCVAFD
  
Inhibitor
Name:
BDBM508753
Synonyms:
5-Chloro-N,N′-dimethyl-picolinamide-3-yl 3-deoxy-3-[4-(2-hydroxythiazol-4-yl)-1H-1,2,3-triazol-1-yl]-1-thio-α-D-galactopyranoside | US11046725, Example 33
Type:
Small organic molecule
Emp. Form.:
C19H21ClN6O6S2
Mol. Mass.:
528.99
SMILES:
CN(C)C(=O)c1ncc(Cl)cc1S[C@H]1OC(CO)[C@H](O)[C@@H](C1O)n1cc(nn1)-c1csc(O)n1 |r|
Structure:
Search PDB for entries with ligand similarity: