Reaction Details Report a problem with these data
Target
Calcitonin gene-related peptide 1
Ligand
BDBM312053
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
Ki
0.050±n/a nM
Citation
 Christopher, JA; Congreve, MS; Bucknell, SJ; Deflorian, F; Pickworth, M; Mason, JS CGRP receptor antagonists US Patent  US10166226 Publication Date 1/1/2019 
Target
Name:
Calcitonin gene-related peptide 1
Synonyms:
CALC1 | CALCA | CALCA_HUMAN | CGRP | Calcitonin gene-related peptide (CGRP alpha) | Calcitonin gene-related peptide 1
Type:
Enzyme
Mol. Mass.:
13902.80
Organism:
Homo sapiens (Human)
Description:
P06881
Residue:
128
Sequence:
MGFQKFSPFLALSILVLLQAGSLHAAPFRSALESSPADPATLSEDEARLLLAALVQDYVQMKASELEQEQEREGSRIIAQKRACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAFGRRRRDLQA
  
Inhibitor
Name:
BDBM312053
Synonyms:
5-{1'-[(2R)-3-(7-methyl-1H-indazol-5-yl)-2-({[4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidin-1-yl]carbonyl}amino)propanoyl]-1,4'-bipiperidin-4-yl}-4H-1,2,4-triazole-3-carboxylic acid | US10166226, Example 9
Type:
Small organic molecule
Emp. Form.:
C39H46N10O5
Mol. Mass.:
734.8465
SMILES:
Cc1cc(C[C@@H](NC(=O)N2CCC(CC2)c2cc3ccccc3[nH]c2=O)C(=O)N2CCC(CC2)N2CCC(CC2)c2nnc([nH]2)C(O)=O)cc2cn[nH]c12 |r|
Structure:
Search PDB for entries with ligand similarity: