Target
Sigma intracellular receptor 2
Ligand
BDBM50374595
Substrate
n/a
Meas. Tech.
Receptor Assay
Ki
0.770±0.06 nM
Citation
 McCurdy, CRMesangeau, CChin, FTJames, MLShen, BGambhir, SBiswal, SBehera, D Highly selective sigma receptor ligands and radioligands as probes in nociceptive processing and the pathphysiological study of memory deficits and cognitive disorders US Patent  US9724435 Publication Date 8/8/2017 
Target
Name:
Sigma intracellular receptor 2
Synonyms:
S2r | SGMR2_RAT | Sigma intracellular receptor 2 | Sigma-2 receptor | Sigma2 receptor | Tmem97 | Transmembrane protein 97
Type:
Protein
Mol. Mass.:
20953.88
Organism:
Rattus norvegicus (Rat)
Description:
Q5U3Y7
Residue:
176
Sequence:
MGAVTARRCVEWLLGLYFVSHIPITMFIDLQALLPPELYPQEFSNLLRWYSKEFKDPLMQEPPVWFKSFLFCELVFQLPFFPIAAYAFFKGSCRWIRIPAIIYAVHTITTLIPILYTILFEDFSKAIAFKGQRPENFRERLTLVGVYAPYLIIPLILLLFMLRNPYYKFEEKRKKK
  
Inhibitor
Name:
BDBM50374595
Synonyms:
CHEMBL272854 | US9604926, Compound CM-372 | US9724435, Compound CM-372
Type:
Small organic molecule
Emp. Form.:
C21H31N3OS
Mol. Mass.:
373.555
SMILES:
S=c1oc2ccccc2n1CCCCN1CCN(CC1)C1CCCCC1
Structure:
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