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TargetSigma non-opioid intracellular receptor 1
LigandBDBM312233
Substrate/Competitorn/a
Meas. Tech.Receptor Assay
Ki 0.310±0.09 nM
Citation McCurdy, CRMesangeau, CChin, FTJames, MLShen, BGambhir, SBiswal, SBehera, D Highly selective sigma receptor ligands and radioligands as probes in nociceptive processing and the pathphysiological study of memory deficits and cognitive disorders US Patent US9724435 Publication Date 8/8/2017
More Info.:Get all data from this article,  Assay Method
 
Sigma non-opioid intracellular receptor 1
Name:Sigma non-opioid intracellular receptor 1
Synonyms:Opioid receptor | Sigma | Sigma opioid receptor | Sigma-1
Type:Enzyme Catalytic Domain
Mol. Mass.:25266.54
Organism:RAT
Description:Q9R0C9
Residue:223
Sequence:
MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRY
WAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
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  Blast E-value cutoff:
BDBM312233
NameBDBM312233
Synonyms:US9604926, Compound AZ-66 | US9724435, Compound AZ-66
TypeSmall organic molecule
Emp. Form.C22H32FN3OS
Mol. Mass.405.572
SMILESCC(CCCn1c2ccc(F)cc2sc1=O)N1CCN(CC1)C1CCCCC1
Structure
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