Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50374607
Substrate
n/a
Meas. Tech.
Receptor Assay
Ki
4.66±0.74 nM
Citation
 McCurdy, CRMesangeau, CChin, FTJames, MLShen, BGambhir, SBiswal, SBehera, D Highly selective sigma receptor ligands and radioligands as probes in nociceptive processing and the pathphysiological study of memory deficits and cognitive disorders US Patent  US9724435 Publication Date 8/8/2017 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
Opioid receptor | Oprs1 | SGMR1_RAT | Sigma | Sigma non-opioid intracellular receptor 1 | Sigma opioid receptor | Sigma-1 | Sigmar1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25266.54
Organism:
RAT
Description:
Q9R0C9
Residue:
223
Sequence:
MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSRLIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRYWAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
  
Inhibitor
Name:
BDBM50374607
Synonyms:
CHEMBL271975 | US9604926, Compound SN-97 | US9724435, Compound SN-97
Type:
Small organic molecule
Emp. Form.:
C19H27N3OS
Mol. Mass.:
345.502
SMILES:
O=c1sc2ccccc2n1CCN1CCN(CC1)C1CCCCC1
Structure:
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