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TargetBRD4 BD1 (aa 42-168)
LigandBDBM348901
Substrate/Competitorn/a
Meas. Tech.BRD4 AlphaLisa Binding Assay
IC50 12464±n/a nM
Citation Romero, FAMagnuson, SRPastor, RTsui, VHMurray, JCrawford, TBurdick, DJAlbrecht, BKCote, ATaylor, AMNasveschuck, CGLeBlanc, YHewitt, MCLai, KWChen, K Therapeutic compounds and uses thereof US Patent US10206931 Publication Date 2/19/2019
More Info.:Get all data from this article,  Assay Method
 
BRD4 BD1 (aa 42-168)
Name:BRD4 BD1 (aa 42-168)
Synonyms:Bromodomain-containing protein 4 Bromo Domain 1
Type:Enzyme Catalytic Domain
Mol. Mass.:15054.68
Organism:Homo sapiens (Human)
Description:n/a
Residue:127
Sequence:
STNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKII
KTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKI
NELPTEE
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM348901
NameBDBM348901
Synonyms:(4R)-4-methyl-6-[(E)-2- | US10206931, Example 3
TypeSmall organic molecule
Emp. Form.C17H17N3O
Mol. Mass.279.3364
SMILESC[C@@H]1CC(=O)Nc2cccc(\C=C\c3ccncc3)c2N1 |r|
Structure
n/a