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Target
Mu-type opioid receptor
Ligand
BDBM364562
Substrate
n/a
Meas. Tech.
Mu-Opioid Receptor Binding Assay
Ki
0.019±0.01 nM
Citation
 Youngman, M Opioid receptor modulating oxabicyclo[2.2.2]octane morphinans US Patent  US9862726 Publication Date 1/9/2018 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM364562
Synonyms:
N-((4bR,6S,8aS,9R)-11- (cyclopropylmethyl)- 3-hydroxy-5,6,7,8,9,10-hexahydro-9,4b- (epiminoethano)-8a,6- (epoxymethano)phenanthren-6- yl)benzamide | US9862726, Compound 27
Type:
Small organic molecule
Emp. Form.:
C28H32N2O3
Mol. Mass.:
444.5653
SMILES:
Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]4(CC5(CC[C@@]34OC5)NC(=O)c3ccccc3)c2c1 |r,TLB:8:7:19:31.4.5|
Structure:
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