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Target
Sphingosine 1-phosphate receptor 1
Ligand
BDBM31071
Substrate
n/a
Meas. Tech.
Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Parental Cell Line Counter Screen 60K MLSMR
EC50
4400±n/a nM
Citation
 PubChem, PC Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Parental Cell Line Counter Screen 60K MLSMR PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 1
Synonyms:
CHEDG1 | EDG1 | Endothelial differentiation G-protein coupled receptor 1 | S1P receptor | S1P1 | S1PR1 | S1PR1_HUMAN | Sphingosine 1-phosphate receptor 1 (S1PR1) | Sphingosine 1-phosphate receptor Edg-1
Type:
Enzyme
Mol. Mass.:
42836.02
Organism:
Homo sapiens (Human)
Description:
P21453
Residue:
382
Sequence:
MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSHPQKDEGDNPETIMSSGNVNSSS
  
Inhibitor
Name:
BDBM31071
Synonyms:
(E)-3-[5-(1-azepanyl)-2-furanyl]-2-(4-fluorophenyl)-2-propenenitrile | (E)-3-[5-(azepan-1-yl)-2-furyl]-2-(4-fluorophenyl)acrylonitrile | (E)-3-[5-(azepan-1-yl)furan-2-yl]-2-(4-fluorophenyl)prop-2-enenitrile | 3-[5-(1-azepanyl)-2-furyl]-2-(4-fluorophenyl)acrylonitrile | MLS000051438 | SMR000079763 | cid_5740802
Type:
Small organic molecule
Emp. Form.:
C19H19FN2O
Mol. Mass.:
310.3654
SMILES:
Fc1ccc(cc1)C(=C/c1ccc(o1)N1CCCCCC1)\C#N
Structure:
Search PDB for entries with ligand similarity: