Reaction Details Report a problem with these data
Target
Diphosphomevalonate decarboxylase
Ligand
BDBM38392
Substrate
n/a
Meas. Tech.
Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - DPM-DC Dose Response
IC50
18965.6±n/a nM
Citation
 PubChem, PC Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - DPM-DC Dose Response PubChem Bioassay (2007)[AID] 
Target
Name:
Diphosphomevalonate decarboxylase
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
35571.44
Organism:
Streptococcus pneumoniae D39
Description:
A0A0H2ZN59
Residue:
317
Sequence:
MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYTETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAAGLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEIYPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLKENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMDAGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC
  
Inhibitor
Name:
BDBM38392
Synonyms:
3-(3,4-dimethoxyphenyl)-7-hydroxy-1-benzopyran-4-one | 3-(3,4-dimethoxyphenyl)-7-hydroxy-4H-chromen-4-one | 3-(3,4-dimethoxyphenyl)-7-hydroxy-chromone | 3-(3,4-dimethoxyphenyl)-7-hydroxychromen-4-one | 3-(3,4-dimethoxyphenyl)-7-oxidanyl-chromen-4-one | MLS000043602 | SMR000020618 | cid_5748605
Type:
Small organic molecule
Emp. Form.:
C17H14O5
Mol. Mass.:
298.2901
SMILES:
COc1ccc(cc1OC)-c1coc2cc(O)ccc2c1=O
Structure:
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