Reaction Details Report a problem with these data
Target
Beta-lactamase
Ligand
BDBM39809
Substrate
n/a
Meas. Tech.
Enzyme Inhibition Assay
pH
7±0
Ki
1.38e+4±n/a nM
Citation
 Caselli, E; Powers, RA; Blasczcak, LC; Wu, CY; Prati, F; Shoichet, BK Energetic, structural, and antimicrobial analyses of beta-lactam side chain recognition by beta-lactamases. Chem Biol 8:17-31 (2001) [PubMed]  Article 
Target
Name:
Beta-lactamase
Synonyms:
BLAC_STAAU | Beta-lactamase TEM | Penicillinase | blaZ
Type:
PROTEIN
Mol. Mass.:
31367.53
Organism:
Staphylococcus aureus
Description:
ChEMBL_41052
Residue:
281
Sequence:
MKKLIFLIVIALVLSACNSNSSHAKELNDLEKKYNAHIGVYALDTKSGKEVKFNSDKRFAYASTSKAINSAILLEQVPYNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGIKKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKKFLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQAITYASRNDVAFVYPKGQSEPIVLVIFTNKDNKSDKPNDKLISETAKSVMKEF
  
Inhibitor
Name:
BDBM39809
Synonyms:
Acylglycineboronic acid, 6
Type:
Small organic molecule
Emp. Form.:
C9H12BNO3
Mol. Mass.:
193.007
SMILES:
OB(O)CNC(=O)Cc1ccccc1
Structure:
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