Reaction Details Report a problem with these data
Target
Galanin receptor type 2
Ligand
BDBM34778
Substrate
n/a
Meas. Tech.
Dose response counterscreen for antagonists of galanin receptor 2 (GalR2): a cell-based high-throughput screening assay for inhibitors of beta-lactamase activity
IC50
>14000±n/a nM
Citation
 PubChem, PC Dose response counterscreen for antagonists of galanin receptor 2 (GalR2): a cell-based high-throughput screening assay for inhibitors of beta-lactamase activity PubChem Bioassay (2008)[AID] 
Target
Name:
Galanin receptor type 2
Synonyms:
GALNR2 | GALR2 | GALR2_HUMAN | Galanin R2 | Galanin receptor 2 | Galanin receptor type 2 | Galanin receptor type 2 (GAL2-R) (GALR2).
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41724.40
Organism:
Homo sapiens (Human)
Description:
Galanin R2 GALR2 HUMAN::O43603
Residue:
387
Sequence:
MNVSGCPGAGNASQAGGGGGWHPEAVIVPLLFALIFLVGTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDGWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLSLLFSGPYLSYYRQSQLANLTVCHPAWSAPRRRAMDICTFVFSYLLPVLVLGLTYARTLRYLWRAVDPVAAGSGARRAKRKVTRMILIVAALFCLCWMPHHALILCVWFGQFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRTICAGLLGRAPGRASGRVCAAARGTHSGSVLERESSDLLHMSEAAGALRPCPGASQPCILEPCPGPSWQGPKAGDSILTVDVA
  
Inhibitor
Name:
BDBM34778
Synonyms:
2-chloranyl-3-[[4-(dimethylamino)phenyl]amino]naphthalene-1,4-dione | 2-chloro-3-[4-(dimethylamino)anilino]-1,4-naphthoquinone | 2-chloro-3-[4-(dimethylamino)anilino]naphthalene-1,4-dione | 2-chloro-3-{[4-(dimethylamino)phenyl]amino}naphthoquinone | MLS000584180 | SMR000203343 | cid_260557
Type:
Small organic molecule
Emp. Form.:
C18H15ClN2O2
Mol. Mass.:
326.777
SMILES:
CN(C)c1ccc(NC2=C(Cl)C(=O)c3ccccc3C2=O)cc1 |c:8|
Structure:
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