Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 1
Ligand
BDBM42521
Substrate
n/a
Meas. Tech.
Dose response counterscreen for neuropeptide Y receptor Y2 (NPY-Y2): Cell-based high throughput assay to measure NPY-Y1 antagonism
IC50
5306±n/a nM
Citation
 PubChem, PC Dose response counterscreen for neuropeptide Y receptor Y2 (NPY-Y2): Cell-based high throughput assay to measure NPY-Y1 antagonism PubChem Bioassay (2008)[AID] 
Target
Name:
Neuropeptide Y receptor type 1
Synonyms:
NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44399.07
Organism:
Homo sapiens (Human)
Description:
NPY-Y1 NPY1R HUMAN::P25929
Residue:
384
Sequence:
MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPVAFKKINNNDDNEKI
  
Inhibitor
Name:
BDBM42521
Synonyms:
4-[(4-tert-butylbenzoyl)amino]-5-chloro-2-methoxy-benzoic acid methyl ester | 4-[[(4-tert-butylphenyl)-oxomethyl]amino]-5-chloro-2-methoxybenzoic acid methyl ester | MLS000571684 | SMR000193693 | cid_1183477 | methyl 4-[(4-tert-butylbenzoyl)amino]-5-chloro-2-methoxybenzoate | methyl 4-[(4-tert-butylphenyl)carbonylamino]-5-chloranyl-2-methoxy-benzoate
Type:
Small organic molecule
Emp. Form.:
C20H22ClNO4
Mol. Mass.:
375.846
SMILES:
COC(=O)c1cc(Cl)c(NC(=O)c2ccc(cc2)C(C)(C)C)cc1OC
Structure:
Search PDB for entries with ligand similarity: