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Target
Tyrosine-protein phosphatase non-receptor type 7
Ligand
BDBM46207
Substrate
n/a
Meas. Tech.
Fluorescent secondary assay for dose-response confirmation of chemical inhibitors of HePTP
IC50
274±n/a nM
Citation
 PubChem, PC Fluorescent secondary assay for dose-response confirmation of chemical inhibitors of HePTP PubChem Bioassay (2009)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 7
Synonyms:
He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:
Protein
Mol. Mass.:
40530.79
Organism:
Homo sapiens (Human)
Description:
P35236
Residue:
360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
  
Inhibitor
Name:
BDBM46207
Synonyms:
4-[[5-(4-bromophenyl)-2-furoyl]thiocarbamoylamino]benzoic acid | 4-[[5-(4-bromophenyl)furan-2-carbonyl]carbamothioylamino]benzoic acid | 4-[[5-(4-bromophenyl)furan-2-yl]carbonylcarbamothioylamino]benzoic acid | 4-[[[[[5-(4-bromophenyl)-2-furanyl]-oxomethyl]amino]-sulfanylidenemethyl]amino]benzoic acid | MLS-0383777.0001 | cid_1328767
Type:
Small organic molecule
Emp. Form.:
C19H13BrN2O4S
Mol. Mass.:
445.287
SMILES:
OC(=O)c1ccc(NC(=S)NC(=O)c2ccc(o2)-c2ccc(Br)cc2)cc1
Structure:
Search PDB for entries with ligand similarity: